Duxin Sun

Overview

Best Publications

• Engineering exosomes as refined biological nanoplatforms for drug delivery.

  Xin Luan;Kanokwan Sansanaphongpricha;Ila Myers;Hongwei Chen

  963
  Citations

• Sulforaphane, a Dietary Component of Broccoli/Broccoli Sprouts, Inhibits Breast Cancer Stem Cells

  Yanyan Li;Tao Zhang;Hasan Korkaya;Suling Liu

  674
  Citations

• A Potent and Selective Small-Molecule Degrader of STAT3 Achieves Complete Tumor Regression In Vivo

  Longchuan Bai;Haibin Zhou;Renqi Xu;Yujun Zhao

  579
  Citations

• Comparison of human duodenum and Caco-2 gene expression profiles for 12,000 gene sequences tags and correlation with permeability of 26 drugs.

  Duxin Sun;Hans Lennernas;Lynda S. Welage;Jeffery L. Barnett

  515
  Citations

• Why is it challenging to predict intestinal drug absorption and oral bioavailability in human using rat model.

  Xianhua Cao;Seth T. Gibbs;Lanyan Fang;Heather A. Miller

  448
  Citations

• A novel Hsp90 inhibitor to disrupt Hsp90/Cdc37 complex against pancreatic cancer cells

  Tao Zhang;Adel Hamza;Xianhua Cao;Bing Wang

  437
  Citations

• Discovery of a Small-Molecule Degrader of Bromodomain and Extra-Terminal (BET) Proteins with Picomolar Cellular Potencies and Capable of Achieving Tumor Regression

  Bing Zhou;Jiantao Hu;Fuming Xu;Zhuo Chen

  367
  Citations

• Pharmacologic Inhibition of the Menin-MLL Interaction Blocks Progression of MLL Leukemia In Vivo.

  Dmitry Borkin;Shihan He;Hongzhi Miao;Katarzyna Kempinska

  359
  Citations

• Withaferin A targets heat shock protein 90 in pancreatic cancer cells.

  Yanke Yu;Adel Hamza;Tao Zhang;Mancang Gu

  355
  Citations

• Aerobic Glycolysis Controls Myeloid-Derived Suppressor Cells and Tumor Immunity via a Specific CEBPB Isoform in Triple-Negative Breast Cancer

  Wei Li;Takashi Tanikawa;Ilona Kryczek;Houjun Xia

  319
  Citations

• Discovery of QCA570 as an Exceptionally Potent and Efficacious Proteolysis Targeting Chimera (PROTAC) Degrader of the Bromodomain and Extra-Terminal (BET) Proteins Capable of Inducing Complete and Durable Tumor Regression

  Chong Qin;Yang Hu;Bing Zhou;Ester Fernandez-Salas

  307
  Citations

• A Potent and Orally Active Antagonist (SM-406/AT-406) of Multiple Inhibitor of Apoptosis Proteins (IAPs) in Clinical Development for Cancer Treatment

  Qian Cai;Haiying Sun;Yuefeng Peng;Yuefeng Peng;Jianfeng Lu

  304
  Citations

• Disruption of 12/15-Lipoxygenase Expression in Peritoneal Macrophages ENHANCED UTILIZATION OF THE 5-LIPOXYGENASE PATHWAY AND DIMINISHED OXIDATION OF LOW DENSITY LIPOPROTEIN

  Duxin Sun;Colin D. Funk

  293
  Citations

• A Potent Small-Molecule Inhibitor of the MDM2–p53 Interaction (MI-888) Achieved Complete and Durable Tumor Regression in Mice

  Yujun Zhao;Shanghai Yu;Wei Sun;Liu Liu

  285
  Citations

• Glucose uptake inhibitor sensitizes cancer cells to daunorubicin and overcomes drug resistance in hypoxia

  Xianhua Cao;Lanyan Fang;Seth Gibbs;Ying Huang

  271
  Citations

• Diastereomeric spirooxindoles as highly potent and efficacious MDM2 inhibitors.

  Yujun Zhao;Liu Liu;Wei Sun;Jianfeng Lu

  253
  Citations

• New developments in Hsp90 inhibitors as anti-cancer therapeutics: mechanisms, clinical perspective and more potential.

  Yanyan Li;Tao Zhang;Steven J. Schwartz;Duxin Sun

  238
  Citations

• Microbial Metabolite Signaling Is Required for Systemic Iron Homeostasis.

  Nupur K. Das;Andrew J. Schwartz;Gabrielle Barthel;Naohiro Inohara

  228
  Citations

• Implications of cancer stem cell theory for cancer chemoprevention by natural dietary compounds.

  Yanyan Li;Max S. Wicha;Steven J. Schwartz;Duxin Sun

  228
  Citations

• Characterization of Celastrol to Inhibit Hsp90 and Cdc37 Interaction

  Tao Zhang;Yanyan Li;Yanke Yu;Peng Zou

  222
  Citations