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Medicine

D-Index
109
Citations
76216
World Ranking
5655
National Ranking
3043

Research.com Recognitions

  • 2000 - Fellow of the American Association for the Advancement of Science (AAAS)
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

Max S. Wicha is affiliated with the University of Michigan-Ann Arbor in the United States. Their research primarily spans the fields of biochemistry, genetics, molecular biology, and medicine, with a strong focus on oncology, molecular biology, cancer research, immunology, and pulmonary and respiratory medicine.

The scientist's work covers several key topics, including:

  • Cancer Cells and Metastasis
  • Cancer Genomics and Diagnostics
  • Immunotherapy and Immune Responses
  • Epigenetics and DNA Methylation
  • RNA modifications and cancer
  • Genomics and Chromatin Dynamics
  • Cancer, Hypoxia, and Metabolism

Frequent publication venues for their research include:

  • Cancer Research
  • Clinical Cancer Research
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Breast Cancer Research and Treatment
  • Oncogene

Max S. Wicha has collaborated extensively with several co-authors, including:

  • Alfred E. Chang
  • Grace G. Bushnell
  • Michael Brooks
  • Sunitha Nagrath
  • You Qin

Recent notable papers published by Max S. Wicha include:

  • The Roles of the Let-7 Family of MicroRNAs in the Regulation of Cancer Stemness (2021, Cells)
  • Utility of Liquid Biopsy Analysis in Detection of Hepatocellular Carcinoma, Determination of Prognosis, and Disease Monitoring: A Systematic Review (2020, Clinical Gastroenterology and Hepatology)
  • A randomized, placebo-controlled phase 2 study of paclitaxel in combination with reparixin compared to paclitaxel alone as front-line therapy for metastatic triple-negative breast cancer (fRida) (2021, Breast Cancer Research and Treatment)
  • Cancer Immunotherapy via Targeting Cancer Stem Cells Using Vaccine Nanodiscs (2020, Nano Letters)
  • High-Throughput Label-Free Isolation of Heterogeneous Circulating Tumor Cells and CTC Clusters from Non-Small-Cell Lung Cancer Patients (2020, Cancers)

Awards received by Max S. Wicha include being named a Fellow of the American Association for the Advancement of Science (AAAS) in 2000 and membership in the Association of American Physicians.

Best Publications

  • Prospective identification of tumorigenic breast cancer cells

    Muhammad Al-Hajj;Max S. Wicha;Adalberto Benito-Hernandez;Sean J. Morrison;Sean J. Morrison

  • ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome.

    Christophe Ginestier;Min Hee Hur;Emmanuelle Charafe-Jauffret;Florence Monville

  • Identification of Pancreatic Cancer Stem Cells

    Chenwei Li;David G. Heidt;Piero Dalerba;Charles F. Burant

  • In vitro propagation and transcriptional profiling of human mammary stem/progenitor cells

    Gabriela Dontu;Wissam M. Abdallah;Jessica M. Foley;Kyle W. Jackson

  • Cancer Stem Cells: An Old Idea--A Paradigm Shift

    M. S Wicha;S. Liu;G. Dontu

  • Chemokines in the cancer microenvironment and their relevance in cancer immunotherapy

    Nisha Nagarsheth;Max S. Wicha;Weiping Zou

  • Hedgehog signaling and Bmi-1 regulate self-renewal of normal and malignant human mammary stem cells.

    Suling Liu;Gabriela Dontu;Ilia D. Mantle;Shivani Patel

  • Breast cancer cell lines contain functional cancer stem cells with metastatic capacity and a distinct molecular signature.

    Emmanuelle Charafe-Jauffret;Christophe Ginestier;Flora Iovino;Julien Wicinski

  • Aldehyde dehydrogenase 1 is a marker for normal and malignant human colonic stem cells (SC) and tracks SC overpopulation during colon tumorigenesis.

    Emina H. Huang;Mark J. Hynes;Tao Zhang;Tao Zhang;Christophe Ginestier

  • Breast cancer stem cells transition between epithelial and mesenchymal states reflective of their normal counterparts

    Suling Liu;Yang Cong;Dong Wang;Yu-Min Sun

  • Role of Notch signaling in cell-fate determination of human mammary stem/progenitor cells

    Gabriela Dontu;Kyle W Jackson;Erin McNicholas;Mari J Kawamura

  • CXCR1 blockade selectively targets human breast cancer stem cells in vitro and in xenografts

    Christophe Ginestier;Suling Liu;Mark E. Diebel;Hasan Korkaya

  • Aldehyde Dehydrogenase 1–Positive Cancer Stem Cells Mediate Metastasis and Poor Clinical Outcome in Inflammatory Breast Cancer

    Emmanuelle Charafe-Jauffret;Christophe Ginestier;Flora Iovino;Carole Tarpin

  • Stem cells in normal breast development and breast cancer

    Gabriela Dontu;Muhammad Al-Hajj;Wissam M. Abdallah;Michael F. Clarke

  • Therapeutic implications of cancer stem cells

    Muhammad Al-Hajj;Michael W Becker;Max Wicha;Irving Weissman

  • Antiangiogenic agents increase breast cancer stem cells via the generation of tumor hypoxia

    Sarah J. Conley;Elizabeth Gheordunescu;Pramod Kakarala;Bryan Newman

  • Stem cells in normal breast development and breast cancer: Stem cells in normal breast development and breast cancer

    Gabriela Dontu;Muhammad Al-Hajj;Wissam M. Abdallah;Michael F. Clarke

  • Breast cancer stem cells, cytokine networks, and the tumor microenvironment

    Hasan Korkaya;Suling Liu;Max S. Wicha

  • HER2 regulates the mammary stem/progenitor cell population driving tumorigenesis and invasion.

    Hasan Korkaya;Amanda Paulson;Flora Iovino;Flora Iovino;Max S. Wicha

  • Breast Cancer Stem Cells Are Regulated by Mesenchymal Stem Cells through Cytokine Networks

    Suling Liu;Christophe Ginestier;Sing J. Ou;Shawn G. Clouthier

Frequent Co-Authors

Suling Liu
Suling Liu Fudan University
Alfred E. Chang
Alfred E. Chang University of Michigan–Ann Arbor
Michael F. Clarke
Michael F. Clarke Stanford University
Sofia D. Merajver
Sofia D. Merajver University of Michigan–Ann Arbor
Duxin Sun
Duxin Sun University of Michigan–Ann Arbor
Lisa A. Newman
Lisa A. Newman Cornell University
Diane M. Simeone
Diane M. Simeone New York University Langone Medical Center
Daniel F. Hayes
Daniel F. Hayes University of Michigan–Ann Arbor

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