World's Best Scientists 2026 revealed!
Martin E. Fernandez-Zapico

Martin E. Fernandez-Zapico

D-Index & Metrics

Biology and Biochemistry

D-Index
67
Citations
23161
World Ranking
8072
National Ranking
3656

Overview

Martin E. Fernandez-Zapico is affiliated with the Mayo Clinic in the United States and has a research focus grounded in biochemistry, genetics, molecular biology, and medicine. Their extensive publication record spans various subfields, particularly molecular biology, oncology, cancer research, genetics, and hematology.

The scientist's work covers a range of main topics including:

  • Pancreatic and Hepatic Oncology Research
  • Epigenetics and DNA Methylation
  • Hedgehog Signaling Pathway Studies
  • Cancer Genomics and Diagnostics
  • Cancer Cells and Metastasis
  • Acute Myeloid Leukemia Research
  • Protein Degradation and Inhibitors

Their recent published papers illustrate active engagement in cutting-edge research. Selected recent papers include:

  • "Hedgehog/GLI Signaling Pathway: Transduction, Regulation, and Implications for Disease," 2021, published in Cancers
  • "RAS mutations drive proliferative chronic myelomonocytic leukemia via a KMT2A-PLK1 axis," 2021, published in Nature Communications
  • "ST3GAL1 is a target of the SOX2-GLI1 transcriptional complex and promotes melanoma metastasis through AXL," 2020, published in Nature Communications
  • "Genomic and Epigenomic Landscaping Defines New Therapeutic Targets for Adenosquamous Carcinoma of the Pancreas," 2020, published in Cancer Research
  • "Culture media composition influences patient-derived organoid ability to predict therapeutic responses in gastrointestinal cancers," 2022, published in JCI Insight

Martin E. Fernandez-Zapico frequently collaborates with other researchers. Regular co-authors include Ryan M. Carr, Luciana L. Almada, Tara L. Hogenson, Ezequiel J. Tolosa, and Ashley N. Sigafoos.

Their publications often appear in the following venues, reflecting the focus and dissemination channels of their work:

  • Cancer Research
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Biological Chemistry
  • Nature Communications
  • JCI Insight

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Stromal elements act to restrain, rather than support, pancreatic ductal adenocarcinoma

    Andrew D. Rhim;Andrew D. Rhim;Paul E. Oberstein;Dafydd H. Thomas;Emily T. Mirek

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • GLI1 is regulated through Smoothened-independent mechanisms in neoplastic pancreatic ducts and mediates PDAC cell survival and transformation

    Olivier Nolan-Stevaux;Janet Lau;Morgan L. Truitt;Gerald C. Chu

  • Glycogen Synthase Kinase-3β Participates in Nuclear Factor κB–Mediated Gene Transcription and Cell Survival in Pancreatic Cancer Cells

    Andrei V. Ougolkov;Martin E. Fernandez-Zapico;Doris N. Savoy;Raul A. Urrutia

  • Transcriptional suppression of mir‐29b‐1/mir‐29a promoter by c‐Myc, hedgehog, and NF‐kappaB

    Justin L. Mott;Satoshi Kurita;Sophie C. Cazanave;Steven F. Bronk

  • Role of transcription factor KLF11 and its diabetes-associated gene variants in pancreatic beta cell function.

    Bernadette Neve;Martin E. Fernandez-Zapico;Vered Ashkenazi-Katalan;Christian Dina

  • Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Ectopic expression of VAV1 reveals an unexpected role in pancreatic cancer tumorigenesis

    Martin E. Fernandez-Zapico;Natalia C. Gonzalez-Paz;Ellen Weiss;Doris N. Savoy

  • Inhibition of glycogen synthase kinase-3 activity leads to epigenetic silencing of nuclear factor κB target genes and induction of apoptosis in chronic lymphocytic leukemia B cells

    Andrei V. Ougolkov;Nancy D. Bone;Martin E. Fernandez-Zapico;Neil E. Kay

  • Evidence for the existence of an HP1-mediated subcode within the histone code.

    Gwen Lomberk;Debora Bensi;Martín E. Fernandez-Zapico;Raul Urrutia

  • Endoplasmic reticulum stress-activated transcription factor ATF6α requires the disulfide isomerase PDIA5 to modulate chemoresistance.

    Arisa Higa;Said Taouji;Stéphanie Lhomond;Devon Jensen

  • Aberrant Nuclear Accumulation of Glycogen Synthase Kinase-3β in Human Pancreatic Cancer: Association with Kinase Activity and Tumor Dedifferentiation

    Andrei V. Ougolkov;Martin E. Fernandez-Zapico;Vladimir N. Bilim;Thomas C. Smyrk

  • Adrenomedullin is Up-regulated in Patients With Pancreatic Cancer and Causes Insulin Resistance in β Cells and Mice

    Gaurav Aggarwal;Vijaya Ramachandran;Naureen Javeed;Thiruvengadam Arumugam

  • Structural and energetic mechanisms of cooperative autoinhibition and activation of Vav1.

    Bingke Yu;Ilídio R.S. Martins;Ilídio R.S. Martins;Pilong Li;Gaya K. Amarasinghe

  • NFAT-induced histone acetylation relay switch promotes c-Myc-dependent growth in pancreatic cancer cells.

    Alexander Köenig;Thomas Linhart;Katrin Schlengemann;Kristina Reutlinger

  • Posttranscriptional Regulation of PER1 Underlies the Oncogenic Function of IREα

    Olivier Pluquet;Nicolas Dejeans;Marion Bouchecareilh;Stephanie Lhomond

  • Hedgehog/GLI Signaling Pathway: Transduction, Regulation, and Implications for Disease

    Ashley N. Sigafoos;Brooke D. Paradise;Martin E. Fernandez-Zapico

  • Targeting galectin-1 inhibits pancreatic cancer progression by modulating tumor-stroma crosstalk.

    Carlos A. Orozco;Neus Martinez-Bosch;Pedro E. Guerrero;Judith Vinaixa

  • Galectin-1 Drives Pancreatic Carcinogenesis through Stroma Remodeling and Hedgehog Signaling Activation

    Neus Martínez-Bosch;Maite G. Fern̊andez-Barrena;Mireia Moreno;Elena Ortiz-Zapater

Frequent Co-Authors

Raul Urrutia
Raul Urrutia Medical College of Wisconsin
Suresh T. Chari
Suresh T. Chari The University of Texas MD Anderson Cancer Center
Terra L. Lasho
Terra L. Lasho Mayo Clinic
Lewis R. Roberts
Lewis R. Roberts Mayo Clinic
Thomas C. Smyrk
Thomas C. Smyrk Mayo Clinic
Eric Solary
Eric Solary Institut Gustave Roussy
Tamas Ordog
Tamas Ordog Mayo Clinic

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