D-Index & Metrics Best Publications
Biology and Biochemistry
Chile
2022

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 83 Citations 54,195 244 World Ranking 2160 National Ranking 2

Research.com Recognitions

Awards & Achievements

2022 - Research.com Biology and Biochemistry in Chile Leader Award

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Apoptosis
  • Cancer

Claudio Hetz mainly investigates Unfolded protein response, Endoplasmic reticulum, Cell biology, Signal transduction and Protein folding. His Unfolded protein response research includes themes of Scrapie, Cancer research, Steatosis, Downregulation and upregulation and Molecular biology. Claudio Hetz is studying ATF6, which is a component of Endoplasmic reticulum.

His Cell biology study integrates concerns from other disciplines, such as XBP1, Autophagy, Apoptosis and Disease. The concepts of his Signal transduction study are interwoven with issues in Transcription factor and Programmed cell death. His work deals with themes such as Sequestosome 1, Computational biology and Effector, which intersect with Programmed cell death.

His most cited work include:

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (4170 citations)
  • Guidelines for the use and interpretation of assays for monitoring autophagy (3242 citations)
  • The unfolded protein response: controlling cell fate decisions under ER stress and beyond (2028 citations)

What are the main themes of his work throughout his whole career to date?

The scientist’s investigation covers issues in Cell biology, Unfolded protein response, Endoplasmic reticulum, Proteostasis and Signal transduction. His study in Cell biology is interdisciplinary in nature, drawing from both Autophagy, Apoptosis, Programmed cell death and Neurodegeneration. His studies deal with areas such as XBP1, Transcription factor, Protein folding, Disease and Neuroscience as well as Unfolded protein response.

His Endoplasmic reticulum research is multidisciplinary, incorporating perspectives in Molecular biology and Cell fate determination. The various areas that Claudio Hetz examines in his Proteostasis study include Proteome, Crosstalk and Neuroprotection. His Signal transduction research incorporates elements of Cancer cell, Cell and Immunology.

He most often published in these fields:

  • Cell biology (79.06%)
  • Unfolded protein response (78.34%)
  • Endoplasmic reticulum (66.06%)

What were the highlights of his more recent work (between 2017-2021)?

  • Unfolded protein response (78.34%)
  • Cell biology (79.06%)
  • Proteostasis (30.69%)

In recent papers he was focusing on the following fields of study:

Claudio Hetz mainly focuses on Unfolded protein response, Cell biology, Proteostasis, Endoplasmic reticulum and Neuroscience. Claudio Hetz interconnects Bioinformatics, Signal transduction, Disease, Tumor progression and Cell fate determination in the investigation of issues within Unfolded protein response. His Cell biology study combines topics from a wide range of disciplines, such as XBP1, Regulator, Transcription factor and Cell migration.

His studies in Endoplasmic reticulum integrate themes in fields like Calcium, Cell, Crosstalk and Homeostasis. His Neuroscience research includes themes of Synaptic plasticity and Programmed cell death, Necroptosis. His work is dedicated to discovering how Programmed cell death, Autophagy are connected with Pathogenesis and other disciplines.

Between 2017 and 2021, his most popular works were:

  • Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018. (1421 citations)
  • The Unfolded Protein Response and Cell Fate Control (448 citations)
  • Endoplasmic reticulum stress signalling and the pathogenesis of non-alcoholic fatty liver disease (178 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Apoptosis
  • Cancer

Claudio Hetz mainly investigates Unfolded protein response, Proteostasis, Endoplasmic reticulum, Cell biology and Neurodegeneration. His work carried out in the field of Unfolded protein response brings together such families of science as Protein aggregation, Crosstalk, Parkinson's disease, Pars compacta and Steatohepatitis. His Proteostasis research integrates issues from Substantia nigra, XBP1, Signal transduction, Disease and Neuroscience.

Claudio Hetz works mostly in the field of Endoplasmic reticulum, limiting it down to concerns involving Cancer research and, occasionally, Transcriptome, Fatty liver, Steatosis and Inflammasome. His Cell biology research incorporates themes from Calcium metabolism, Calcium and Cytoskeleton. The study incorporates disciplines such as Secretion, Cell Fate Control, ATF6, Kinase activity and Secretory pathway in addition to Neurodegeneration.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

Daniel J. Klionsky;Amal Kamal Abdel-Aziz;Sara Abdelfatah;Mahmoud Abdellatif.
Autophagy (2021)

8964 Citations

Guidelines for the use and interpretation of assays for monitoring autophagy

Daniel J. Klionsky;Fabio C. Abdalla;Hagai Abeliovich;Robert T. Abraham.
Autophagy (2012)

8302 Citations

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin.
Autophagy (2016)

7788 Citations

The unfolded protein response: controlling cell fate decisions under ER stress and beyond

Claudio Hetz;Claudio Hetz.
Nature Reviews Molecular Cell Biology (2012)

3287 Citations

In Vitro Generation of Infectious Scrapie Prions

Joaquín Castilla;Paula Saá;Paula Saá;Claudio Hetz;Claudio Hetz;Claudio Soto.
Cell (2005)

957 Citations

Cyclophilin D is a component of mitochondrial permeability transition and mediates neuronal cell death after focal cerebral ischemia.

Anna C. Schinzel;Osamu Takeuchi;Zhihong Huang;Jill K. Fisher.
Proceedings of the National Academy of Sciences of the United States of America (2005)

902 Citations

Targeting the unfolded protein response in disease

Claudio Hetz;Eric Chevet;Heather P. Harding.
Nature Reviews Drug Discovery (2013)

806 Citations

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018

Lorenzo Galluzzi;Ilio Vitale;Stuart A. Aaronson;John M. Abrams.
Nature (2018)

784 Citations

Proapoptotic BAX and BAK modulate the unfolded protein response by a direct interaction with IRE1alpha.

Claudio Hetz;Paula Bernasconi;Jill Fisher;Ann-Hwee Lee.
Science (2006)

703 Citations

The Unfolded Protein Response and Cell Fate Control

Claudio Hetz;Feroz R. Papa.
Molecular Cell (2018)

676 Citations

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