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D-Index & Metrics

Biology and Biochemistry

D-Index
80
Citations
40952
World Ranking
3983
National Ranking
19

Research.com Recognitions

  • 2020 - Member of the Royal Irish Academy

Overview

Afshin Samali is affiliated with the National University of Ireland, Galway. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, with a significant focus also in Medicine.

Their work covers several subfields including Molecular Biology, Cell Biology, Epidemiology, Cancer Research, and Genetics. Research topics prominently feature Endoplasmic Reticulum Stress and Disease, RNA regulation and disease, Autophagy in Disease and Therapy, Mitochondrial Function and Pathology, Heat shock proteins research, RNA Interference and Gene Delivery, and Metal complexes synthesis and properties.

Frequent publication venues for Afshin Samali include the Journal of Cellular and Molecular Medicine, Cells, Cancers, Cancer Letters, and Cellular and Molecular Life Sciences.

Collaborations with other researchers appear regularly, with frequent co-authors including:

  • Adrienne M. Gorman
  • Katarzyna Mnich
  • John B. Patterson
  • Éric Chevet
  • Susan E. Logue

The scientist's recent papers highlight various aspects of cellular stress responses and cancer research. Some notable publications are:

  • Regulation of lipid metabolism by the unfolded protein response, 2021, Journal of Cellular and Molecular Medicine
  • Tumour Cell Secretome in Chemoresistance and Tumour Recurrence, 2020, Trends in Cancer
  • ER stress in obesity pathogenesis and management, 2021, Trends in Pharmacological Sciences
  • Local intracerebral inhibition of IRE1 by MKC8866 sensitizes glioblastoma to irradiation/chemotherapy in vivo, 2020, Cancer Letters
  • Simvastatin Induces Unfolded Protein Response and Enhances Temozolomide-Induced Cell Death in Glioblastoma Cells, 2020, Cells

In 2020, Afshin Samali was named a Member of the Royal Irish Academy.

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Mediators of endoplasmic reticulum stress-induced apoptosis.

    Eva Szegezdi;Susan E Logue;Adrienne M Gorman;Afshin Samali

  • The integrated stress response.

    Karolina Pakos‐Zebrucka;Izabela Koryga;Katarzyna Mnich;Mila Ljujic

  • Triggering and modulation of apoptosis by oxidative stress.

    Joya Chandra;Afshin Samali;Sten Orrenius

  • Cellular Stress Responses: Cell Survival and Cell Death

    Simone Fulda;Adrienne M. Gorman;Osamu Hori;Afshin Samali

  • The eIF2α kinases: their structures and functions

    Neysan Donnelly;Adrienne M. Gorman;Sanjeev Gupta;Afshin Samali

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Endoplasmic Reticulum Stress signalling - from basic mechanisms to clinical applications

    Aitor Almanza;Antonio Carlesso;Chetan Chintha;Stuart Creedican

  • PERK is required at the ER-mitochondrial contact sites to convey apoptosis after ROS-based ER stress

    Verfaillie T;Rubio N;Rubio N;Garg Ad;Bultynck G

  • Heat Shock Proteins Increase Resistance to Apoptosis

    Afshin Samali;Thomas G. Cotter

  • Presence of a pre-apoptotic complex of pro-caspase-3, Hsp60 and Hsp10 in the mitochondrial fraction of jurkat cells.

    Afshin Samali;Jiyang Cai;Boris Zhivotovsky;Dean P. Jones

  • On the role of Hsp27 in regulating apoptosis.

    C. G. Concannon;A. M. Gorman;A. Samali

  • Caspase-12 and ER-stress-mediated apoptosis: the story so far.

    Eva Szegezdi;Una Fitzgerald;Afshin Samali

  • Caspases: their intracellular localization and translocation during apoptosis.

    Boris Zhivotovsky;Afshin Samali;Annie Gahm;Sten Orrenius

  • Stress management at the ER: regulators of ER stress-induced apoptosis.

    Adrienne M. Gorman;Sandra J.M. Healy;Richard Jäger;Afshin Samali

  • Losing heart: the role of apoptosis in heart disease—a novel therapeutic target?

    Catherine Gill;Ruben Mestril;Afshin Samali

  • Heat shock proteins: regulators of stress response and apoptosis

    Afshin Samali;Sten Orrenius

  • Targeting the endoplasmic reticulum-stress response as an anticancer strategy.

    Sandra J.M. Healy;Adrienne M. Gorman;Parisa Mousavi-Shafaei;Sanjeev Gupta

  • Unfolded proteins and endoplasmic reticulum stress in neurodegenerative disorders

    Karen M Doyle;Donna Kennedy;Adrienne M Gorman;Sanjeev Gupta

  • TRAIL receptor signalling and modulation: Are we on the right TRAIL?

    Devalingam Mahalingam;Eva Szegezdi;Maccon Keane;Steven de Jong

Frequent Co-Authors

Adrienne M. Gorman
Adrienne M. Gorman University of Galway
Wim J. Quax
Wim J. Quax University of Groningen
Sten Orrenius
Sten Orrenius Karolinska Institute
Luis Serrano
Luis Serrano Centre for Genomic Regulation
Boris Zhivotovsky
Boris Zhivotovsky Karolinska Institute
Timothy O'Brien
Timothy O'Brien University of Minnesota
Saeid Ghavami
Saeid Ghavami University of Manitoba
Leif A. Eriksson
Leif A. Eriksson University of Gothenburg
Claudio Hetz
Claudio Hetz University of Chile

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