Laurie H. Glimcher

Research.com Recognitions

• 2026 - Research.com Immunology in United States Leader Award
• 2025 - Research.com Best Female Scientists Award
• 2025 - Research.com Immunology in United States Leader Award
• 2019 - Distinguished Fellows of the American Association of Immunologists (AAI)
• 2018 - AAI Lifetime Achievement Award, American Association of Immunologists
• 2018 - American Association of Immunologists Lifetime Achievement Award
• 2009 - Fellow of the American Association for the Advancement of Science (AAAS)
• 2008 - AAI Excellence in Mentoring Award, American Association of Immunologists
• 2002 - Member of the National Academy of Sciences
• 2001 - Excellence in Science Award, Federation of American Societies for Experimental Biology (FASEB)
• 1998 - Member of the National Academy of Medicine (NAM)
• 1996 - Fellow of the American Academy of Arts and Sciences
• Member of the Association of American Physicians
• Member of the Association of American Physicians
• Member of the Association of American Physicians
• Member of the Association of American Physicians
• Member of the Association of American Physicians

Overview

Best Publications

• A novel transcription factor, T-bet, directs Th1 lineage commitment.

  Susanne J Szabo;Sean T Kim;Gina L Costa;Xiankui Zhang

  5691
  Citations

• Endoplasmic Reticulum Stress Links Obesity, Insulin Action, and Type 2 Diabetes

  Umut Özcan;Qiong Cao;Erkan Yilmaz;Ann-Hwee Lee

  4652
  Citations

• XBP-1 Regulates a Subset of Endoplasmic Reticulum Resident Chaperone Genes in the Unfolded Protein Response

  Ann-Hwee Lee;Neal N. Iwakoshi;Laurie H. Glimcher

  2515
  Citations

• B7-1 and B7-2 costimulatory molecules activate differentially the Th1/Th2 developmental pathways: Application to autoimmune disease therapy

  Vijay K Kuchroo;Mercy Prabhu Das;Julia A Brown;Ann M Ranger

  2134
  Citations

• Distinct effects of T-bet in TH1 lineage commitment and IFN-γ production in CD4 and CD8 T cells

  Susanne J. Szabo;Brandon M. Sullivan;Claudia Stemmann;Abhay R. Satoskar

  1696
  Citations

• XBP1 links ER stress to intestinal inflammation and confers genetic risk for human inflammatory bowel disease

  Arthur Kaser;Ann-Hwee Lee;Andre Franke;Jonathan N. Glickman

  1646
  Citations

• Plasma cell differentiation requires the transcription factor XBP-1

  Andreas M. Reimold;Neal N. Iwakoshi;John Manis;Prashanth Vallabhajosyula

  1566
  Citations

• Molecular Mechanisms RegulatinG Th1 Immune Responses

  Susanne J. Szabo;Brandon M. Sullivan;Stanford L. Peng;Laurie H. Glimcher

  1467
  Citations

• XBP1, downstream of Blimp-1, expands the secretory apparatus and other organelles, and increases protein synthesis in plasma cell differentiation.

  A.L Shaffer;Miriam Shapiro-Shelef;Neal N Iwakoshi;Ann-Hwee Lee

  1227
  Citations

• Regulation of hepatic lipogenesis by the transcription factor XBP1

  Ann-Hwee Lee;Erez F. Scapa;Erez F. Scapa;David E. Cohen;David E. Cohen;Laurie H. Glimcher

  1148
  Citations

• Communicable Ulcerative Colitis Induced by T-bet Deficiency in the Innate Immune System

  Wendy S. Garrett;Graham M. Lord;Graham M. Lord;Graham M. Lord;Shivesh Punit;Geanncarlo Lugo-Villarino

  1126
  Citations

• TLR activation of the transcription factor XBP1 regulates innate immune responses in macrophages

  Fabio Martinon;Xi Chen;Ann-Hwee Lee;Laurie H Glimcher;Laurie H Glimcher

  1124
  Citations

• Plasma cell differentiation and the unfolded protein response intersect at the transcription factor XBP-1.

  Neal N. Iwakoshi;Ann-Hwee Lee;Prasanth Vallabhajosyula;Kevin L. Otipoby

  1095
  Citations

• Spontaneous development of inflammatory bowel disease in T cell receptor mutant mice

  Peter Mombaerts;Emiko Mizoguchi;Michael J. Grusby;Laurie H. Glimcher

  1074
  Citations

• The Proto-Oncogene c-maf Is Responsible for Tissue-Specific Expression of Interleukin-4

  I-Cheng Ho;Martin R Hodge;John W Rooney;Laurie H Glimcher

  1007
  Citations

• Homeostasis and Inflammation in the Intestine

  Wendy S. Garrett;Jeffrey I. Gordon;Laurie H. Glimcher

  968
  Citations

• ER Stress Sensor XBP1 Controls Anti-tumor Immunity by Disrupting Dendritic Cell Homeostasis

  Juan R. Cubillos-Ruiz;Pedro C. Silberman;Melanie R. Rutkowski;Sahil Chopra

  960
  Citations

• Development of Spontaneous Airway Changes Consistent with Human Asthma in Mice Lacking T-bet

  Susetta Finotto;Markus F. Neurath;Jonathan N. Glickman;Shixin Qin

  927
  Citations

• XBP1 promotes triple-negative breast cancer by controlling the HIF1α pathway

  Xi Chen;Dimitrios Iliopoulos;Dimitrios Iliopoulos;Qing Zhang;Qianzi Tang;Qianzi Tang

  924
  Citations

• Tumorigenic and Immunosuppressive Effects of Endoplasmic Reticulum Stress in Cancer

  Juan R. Cubillos-Ruiz;Sarah E. Bettigole;Laurie H. Glimcher;Laurie H. Glimcher

  903
  Citations

• T-bet Regulates the Terminal Maturation and Homeostasis of NK and Vα14i NKT Cells

  Michael J Townsend;Amy S Weinmann;Jennifer L Matsuda;Rachelle Salomon

  898
  Citations

• The role of Th1/Th2 polarization in mucosal immunity

  Markus F Neurath;Susetta Finotto;Laurie H Glimcher

  840
  Citations