D-Index & Metrics Best Publications
Research.com 2022 Best Female Scientist Award Badge
Immunology
USA
2023

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Best female scientists D-index 155 Citations 93,790 490 World Ranking 78 National Ranking 54
Immunology D-index 133 Citations 70,394 360 World Ranking 119 National Ranking 80
Medicine D-index 147 Citations 87,809 459 World Ranking 691 National Ranking 412

Research.com Recognitions

Awards & Achievements

2023 - Research.com Immunology in United States Leader Award

2022 - Research.com Best Female Scientist Award

2019 - Distinguished Fellows of the American Association of Immunologists (AAI)

2018 - American Association of Immunologists Lifetime Achievement Award

2018 - AAI Lifetime Achievement Award, American Association of Immunologists

2009 - Fellow of the American Association for the Advancement of Science (AAAS)

2008 - AAI Excellence in Mentoring Award, American Association of Immunologists

2002 - Member of the National Academy of Sciences

2001 - Excellence in Science Award, Federation of American Societies for Experimental Biology (FASEB)

1998 - Member of the National Academy of Medicine (NAM)

1996 - Fellow of the American Academy of Arts and Sciences

Member of the Association of American Physicians

Overview

What is she best known for?

The fields of study she is best known for:

  • Gene
  • Immune system
  • Cytokine

Laurie H. Glimcher focuses on Transcription factor, Immunology, Cell biology, Molecular biology and Unfolded protein response. Her research integrates issues of Cytokine, Interleukin 4, Regulation of gene expression and Cellular differentiation in her study of Transcription factor. As part of her studies on Immunology, Laurie H. Glimcher often connects relevant subjects like Inflammatory bowel disease.

Her studies deal with areas such as Natural killer T cell, Plasma cell differentiation and Antigen-presenting cell as well as Cell biology. Her work investigates the relationship between Molecular biology and topics such as Transcription that intersect with problems in CD40 and RAR-related orphan receptor gamma. Her Unfolded protein response research incorporates themes from XBP1, X-Box Binding Protein 1, Signal transduction and Endocrinology.

Her most cited work include:

  • Endoplasmic Reticulum Stress Links Obesity, Insulin Action, and Type 2 Diabetes (3050 citations)
  • A novel transcription factor, T-bet, directs Th1 lineage commitment. (2920 citations)
  • XBP-1 Regulates a Subset of Endoplasmic Reticulum Resident Chaperone Genes in the Unfolded Protein Response (1649 citations)

What are the main themes of her work throughout her whole career to date?

Her scientific interests lie mostly in Cell biology, Molecular biology, Immunology, Transcription factor and T cell. Laurie H. Glimcher has included themes like Cellular differentiation and Osteoblast in her Cell biology study. In her study, CD8 is strongly linked to Major histocompatibility complex, which falls under the umbrella field of Molecular biology.

Her Immunology study frequently intersects with other fields, such as Cytotoxic T cell. Her Transcription factor research is multidisciplinary, incorporating perspectives in Chromatin, Endocrinology and Interleukin 4. Her Unfolded protein response study integrates concerns from other disciplines, such as XBP1 and X-Box Binding Protein 1.

She most often published in these fields:

  • Cell biology (42.91%)
  • Molecular biology (36.40%)
  • Immunology (34.87%)

What were the highlights of her more recent work (between 2010-2021)?

  • Cell biology (42.91%)
  • XBP1 (12.64%)
  • Transcription factor (28.54%)

In recent papers she was focusing on the following fields of study:

The scientist’s investigation covers issues in Cell biology, XBP1, Transcription factor, Immunology and Unfolded protein response. The study incorporates disciplines such as Molecular biology, Innate immune system, RUNX2 and Cellular differentiation in addition to Cell biology. Her work carried out in the field of Molecular biology brings together such families of science as DNA-binding domain and Acetaminophen.

The various areas that Laurie H. Glimcher examines in her Transcription factor study include Chromatin, Regulation of gene expression, Internal medicine and Endocrinology. Immunology is frequently linked to Stimulation in her study. Her Unfolded protein response study is concerned with the field of Endoplasmic reticulum as a whole.

Between 2010 and 2021, her most popular works were:

  • XBP1 promotes triple-negative breast cancer by controlling the HIF1α pathway (473 citations)
  • The Unfolded Protein Response: Integrating Stress Signals Through the Stress Sensor IRE1α (414 citations)
  • ER Stress Sensor XBP1 Controls Anti-tumor Immunity by Disrupting Dendritic Cell Homeostasis (385 citations)

In her most recent research, the most cited papers focused on:

  • Gene
  • Immune system
  • Cytokine

Her primary scientific interests are in XBP1, Unfolded protein response, Cell biology, Endoplasmic reticulum and Transcription factor. Her work deals with themes such as Lipid metabolism, Internal medicine, Endocrinology and Gene silencing, which intersect with Unfolded protein response. The concepts of her Cell biology study are interwoven with issues in Autophagy, Long-term potentiation and Innate immune system.

Her Endoplasmic reticulum study combines topics in areas such as Cancer research, Immune system, Immunology, Immunity and Function. Her Immunology research incorporates elements of Ex vivo, Intestinal mucosa and Inflammatory bowel disease. Her biological study spans a wide range of topics, including Molecular biology, Signal transduction, Lipoprotein lipase and Cellular differentiation.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

A novel transcription factor, T-bet, directs Th1 lineage commitment.

Susanne J Szabo;Sean T Kim;Gina L Costa;Xiankui Zhang.
Cell (2000)

5299 Citations

Endoplasmic Reticulum Stress Links Obesity, Insulin Action, and Type 2 Diabetes

Umut Özcan;Qiong Cao;Erkan Yilmaz;Ann-Hwee Lee.
Science (2004)

4244 Citations

XBP-1 Regulates a Subset of Endoplasmic Reticulum Resident Chaperone Genes in the Unfolded Protein Response

Ann-Hwee Lee;Neal N. Iwakoshi;Laurie H. Glimcher.
Molecular and Cellular Biology (2003)

2232 Citations

B7-1 and B7-2 costimulatory molecules activate differentially the Th1/Th2 developmental pathways: Application to autoimmune disease therapy

Vijay K Kuchroo;Mercy Prabhu Das;Julia A Brown;Ann M Ranger.
Cell (1995)

2120 Citations

Distinct effects of T-bet in TH1 lineage commitment and IFN-γ production in CD4 and CD8 T cells

Susanne J. Szabo;Brandon M. Sullivan;Claudia Stemmann;Abhay R. Satoskar.
Science (2002)

1614 Citations

XBP1 links ER stress to intestinal inflammation and confers genetic risk for human inflammatory bowel disease

Arthur Kaser;Ann-Hwee Lee;Andre Franke;Jonathan N. Glickman.
Cell (2008)

1426 Citations

Plasma cell differentiation requires the transcription factor XBP-1

Andreas M. Reimold;Neal N. Iwakoshi;John Manis;Prashanth Vallabhajosyula.
Nature (2001)

1423 Citations

Molecular Mechanisms RegulatinG Th1 Immune Responses

Susanne J. Szabo;Brandon M. Sullivan;Stanford L. Peng;Laurie H. Glimcher.
Annual Review of Immunology (2003)

1388 Citations

XBP1, downstream of Blimp-1, expands the secretory apparatus and other organelles, and increases protein synthesis in plasma cell differentiation.

A.L Shaffer;Miriam Shapiro-Shelef;Neal N Iwakoshi;Ann-Hwee Lee.
Immunity (2004)

1070 Citations

Spontaneous development of inflammatory bowel disease in T cell receptor mutant mice

Peter Mombaerts;Emiko Mizoguchi;Michael J. Grusby;Laurie H. Glimcher.
Cell (1993)

1053 Citations

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