D-Index & Metrics Best Publications
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D-Index & Metrics

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Immunology D-index 125 Citations 61,475 321 World Ranking 95 National Ranking 65
Medicine D-index 128 Citations 66,817 338 World Ranking 1079 National Ranking 646
Best female scientists D-index 144 Citations 84,320 433 World Ranking 125 National Ranking 81

Research.com Recognitions

Awards & Achievements

2022 - Research.com Best Female Scientist Award

2019 - Distinguished Fellows of the American Association of Immunologists (AAI)

2011 - Fellow of the American Association for the Advancement of Science (AAAS)

2008 - Member of the National Academy of Medicine (NAM)

2003 - American Association of Immunologists Lifetime Achievement Award

2003 - AAI Lifetime Achievement Award, American Association of Immunologists

1997 - Fellow of the Royal Society, United Kingdom

1994 - Louisa Gross Horwitz Prize, Columbia University

1993 - Paul Ehrlich and Ludwig Darmstaedter Prize

1991 - Fellow of the American Academy of Arts and Sciences

1989 - Member of the National Academy of Sciences

Overview

What is she best known for?

The fields of study she is best known for:

  • Gene
  • Immune system
  • Antigen

Philippa Marrack mainly focuses on T cell, Antigen, Cytotoxic T cell, Major histocompatibility complex and Cell biology. To a larger extent, Philippa Marrack studies Immunology with the aim of understanding T cell. Her Antigen study combines topics from a wide range of disciplines, such as Biochemistry and Antibody, B cell.

Her research on Cytotoxic T cell often connects related topics like CD8. Within one scientific family, Philippa Marrack focuses on topics pertaining to T-cell receptor under Major histocompatibility complex, and may sometimes address concerns connected to Superantigen, Receptor and Virology. Philippa Marrack focuses mostly in the field of Cell biology, narrowing it down to matters related to Apoptosis and, in some cases, In vivo and Membrane protein.

Her most cited work include:

  • T cell tolerance by clonal elimination in the thymus (1954 citations)
  • The staphylococcal enterotoxins and their relatives (1725 citations)
  • The Vβ-specific superantigen staphylococcal enterotoxin B: Stimulation of mature T cells and clonal deletion in neonatal mice (911 citations)

What are the main themes of her work throughout her whole career to date?

Her primary areas of study are T cell, Antigen, Molecular biology, Immunology and Major histocompatibility complex. Her T cell research incorporates themes from Cytotoxic T cell, Peptide, B cell and Cell biology. The Cell biology study combines topics in areas such as Apoptosis and Cell.

The study incorporates disciplines such as Antibody and Antigen presentation in addition to Antigen. Her Molecular biology research is multidisciplinary, incorporating elements of CD8, Interleukin 2, Peptide sequence, Gene and Epitope. Her Major histocompatibility complex study incorporates themes from Superantigen and T-cell receptor.

She most often published in these fields:

  • T cell (53.62%)
  • Antigen (49.90%)
  • Molecular biology (47.36%)

What were the highlights of her more recent work (between 2011-2021)?

  • Immunology (43.84%)
  • Antigen (49.90%)
  • Major histocompatibility complex (44.03%)

In recent papers she was focusing on the following fields of study:

Philippa Marrack mostly deals with Immunology, Antigen, Major histocompatibility complex, Cell biology and Molecular biology. Her Antigen research includes themes of Adjuvant and Cell. Her work deals with themes such as Mutation, Mutant, Allele and T-cell receptor, which intersect with Major histocompatibility complex.

Her Cell biology research is multidisciplinary, incorporating perspectives in Cloning and Gene. Philippa Marrack has researched Molecular biology in several fields, including Transcription factor, Monoclonal antibody and MHC class II. Her T cell study also includes

  • Cytotoxic T cell which intersects with area such as CD8,
  • Epitope and Human leukocyte antigen most often made with reference to Peptide.

Between 2011 and 2021, her most popular works were:

  • T-box transcription factor T-bet, a key player in a unique type of B-cell activation essential for effective viral clearance (134 citations)
  • Age-Associated B Cells: A T-bet-Dependent Effector with Roles in Protective and Pathogenic Immunity. (106 citations)
  • Old and new adjuvants (96 citations)

In her most recent research, the most cited papers focused on:

  • Gene
  • Immune system
  • Antibody

Philippa Marrack mainly investigates Immunology, T cell, Molecular biology, Autoimmunity and Antigen. Her work on Immune system, IL-2 receptor, Inflammation and Immunity as part of general Immunology study is frequently connected to Target tissue, therefore bridging the gap between diverse disciplines of science and establishing a new relationship between them. Her T cell research incorporates elements of Beryllium Disease, Cytotoxic T cell, Human leukocyte antigen and Peptide.

Philippa Marrack combines subjects such as Peptide sequence, MHC class II and Antigen-presenting cell with her study of Molecular biology. A large part of her Antigen studies is devoted to Major histocompatibility complex. Her biological study spans a wide range of topics, including Natural killer T cell, CD8 and Ligand.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

T cell tolerance by clonal elimination in the thymus

John W. Kappler;Neal Roehm;Philippa Marrack.
Cell (1987)

3192 Citations

The staphylococcal enterotoxins and their relatives

Philippa Marrack;John Kappler.
Science (1990)

2748 Citations

Self-tolerance eliminates T cells specific for Mls-modified products of the major histocompatibility complex

John W. Kappler;Uwe Staerz;Janice White;Philippa C. Marrack;Philippa C. Marrack.
Nature (1988)

1424 Citations

The Vβ-specific superantigen staphylococcal enterotoxin B: Stimulation of mature T cells and clonal deletion in neonatal mice

Janice White;Andrew Herman;Ann M. Pullen;Ralph Kubo.
Cell (1989)

1416 Citations

Antigen-inducible, H-2-restricted, interleukin-2-producing T cell hybridomas. Lack of independent antigen and H-2 recognition

John W. Kappler;Barry Skidmore;Janice White;Philippa Marrack.
Journal of Experimental Medicine (1981)

1402 Citations

Interaction of Staphylococcus aureus toxin "superantigens" with human T cells.

Yongwon Choi;Brian Kotzin;Lynne Herron;Jill Callahan.
Proceedings of the National Academy of Sciences of the United States of America (1989)

1376 Citations

Characterization of the Murine Antigenic Determinant, Designated L3T4a, Recognized by Monoclonal Antibody GK 1.5: Expression of L3T4a by Functional T Cell Clones Appears to Correlate Primarily with Class II MHC Antigen‐Reactivity

D. P. Dialynas;D. B. Wilde;P. Marrack;A. Pierres.
Immunological Reviews (1983)

1350 Citations

Normal development of mice deficient in beta 2M, MHC class I proteins, and CD8+ T cells

Beverly H. Koller;Philippa Marrack;John W. Kappler;Oliver Smithies.
Science (1990)

1206 Citations

The major histocompatibility complex-restricted antigen receptor on T cells. I. Isolation with a monoclonal antibody.

K Haskins;R Kubo;J White;M Pigeon.
Journal of Experimental Medicine (1983)

1199 Citations

Type I Interferons Keep Activated T Cells Alive

Philippa Marrack;John Kappler;Tom Mitchell.
Journal of Experimental Medicine (1999)

1109 Citations

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