2026 David M. Kranz: Molecular Biology Researcher – H-Index, Publications & Awards

Discipline name	D-Index	World Ranking	Current World Ranking	National Ranking	Current National Ranking	Publications	Citations
Molecular Biology	78	1073	953	559	486	284	23699

Research.com Recognitions

2019 - Fellow, National Academy of Inventors

Overview

David M. Kranz is affiliated with the University of Illinois at Urbana-Champaign in the United States. Their research primarily spans the field of Medicine with a focus on oncology, infectious diseases, immunology, molecular biology, and radiology, nuclear medicine, and imaging.

The scientist's work is concentrated on several main topics, including:

CAR-T cell therapy research
SARS-CoV-2 and COVID-19 research
SARS-CoV-2 detection and testing
Monoclonal and polyclonal antibodies research
Immunotherapy and immune responses
COVID-19 epidemiological studies
Immune cell function and interaction

Frequent co-authors collaborating with David M. Kranz include:

Preeti Sharma
Diana Rose E. Rañoa
Venkata V.V.R. Marada
Steven P. Wolf
Karin Schreiber

Common publication venues for their research work are:

Journal for ImmunoTherapy of Cancer
Cancer Research
Science
Neuro-Oncology
Proceedings of the National Academy of Sciences

Notable recent papers by David M. Kranz include:

"Engineering human ACE2 to optimize binding to the spike protein of SARS coronavirus 2," 2020, Science
"Treatment of an aggressive orthotopic murine glioblastoma model with combination checkpoint blockade and a multivalent neoantigen vaccine," 2020, Neuro-Oncology
"Structure-guided engineering of the affinity and specificity of CARs against Tn-glycopeptides," 2020, Proceedings of the National Academy of Sciences
"Mitigation of SARS-CoV-2 transmission at a large public university," 2022, Nature Communications
"TCR-engineered adoptive cell therapy effectively treats intracranial murine glioblastoma," 2023, Journal for ImmunoTherapy of Cancer

David M. Kranz was awarded the title of Fellow of the National Academy of Inventors in 2019.

Best Publications

Host type I IFN signals are required for antitumor CD8+ T cell responses through CD8α+ dendritic cells

Mercedes B. Fuertes;Aalok K. Kacha;Justin Kline;Seng Ryong Woo

1327
Citations
Positive and negative selection of an antigen receptor on T cells in transgenic mice

William C. Sha;Christopher A. Nelson;Rodney D. Newberry;David M. Kranz

934
Citations
Complete primary structure of a heterodimeric T-cell receptor deduced from cDNA sequences.

Haruo Saito;David M. Kranz;Yohtaroh Takagaki;Adrian C. Hayday

847
Citations
APRIL: a processor architecture for multiprocessing

Anant Agarwal;Beng-Hong Lim;David Kranz;John Kubiatowicz

727
Citations
A third rearranged and expressed gene in a clone of cytotoxic T lymphocytes.

Haruo Saito;David M. Kranz;Yohtaroh Takagaki;Adrian C. Hayday

643
Citations
Selective expression of an antigen receptor on CD8-bearing T lymphocytes in transgenic mice.

W C Sha;C A Nelson;R D Newberry;D M Kranz

612
Citations
Engineered CAR T Cells Targeting the Cancer-Associated Tn-Glycoform of the Membrane Mucin MUC1 Control Adenocarcinoma.

Avery D. Posey;Robert D. Schwab;Alina C. Boesteanu;Catharina Steentoft

602
Citations
Engineering human ACE2 to optimize binding to the spike protein of SARS coronavirus 2.

Kui K. Chan;Danielle Dorosky;Preeti Sharma;Shawn A. Abbasi

590
Citations
The MIT Alewife machine: architecture and performance

Anant Agarwal;Ricardo Bianchini;David Chaiken;Kirk L. Johnson

579
Citations
Structure, organization, and somatic rearrangement of T cell gamma genes

Adrian C. Hayday;Haruo Saito;Stephen D. Gillies;David M. Kranz

531
Citations
T-cell receptor binding affinities and kinetics: impact on T-cell activity and specificity.

Jennifer D. Stone;Adam S. Chervin;David M. Kranz

457
Citations
Quantitative Analysis of the Contribution of TCR/pepMHC Affinity and CD8 to T Cell Activation

Phillip D. Holler;David M. Kranz

443
Citations
Induced sensitization of tumor stroma leads to eradication of established cancer by T cells

Bin Zhang;Natalie A. Bowerman;Joseph K. Salama;Hank Schmidt

412
Citations
THE MIT ALEWIFE MACHINE: A LARGE-SCALE DISTRIBUTED-MEMORY MULTIPROCESSOR

A. Agarwal;D. Chaiken;K. Johnson;D. Kranz

403
Citations
In vitro evolution of a T cell receptor with high affinity for peptide/MHC

Phillip D. Holler;Philmore O. Holman;Eric V. Shusta;Sean O'Herrin

398
Citations
Yeast cell surface display of proteins and uses thereof

Dane K. Wittrup;Michele C. Kieke;David M. Kranz;Eric Shusta

380
Citations
Efficient tumor cell lysis mediated by a bispecific single chain antibody expressed in Escherichia coli.

Meegan Gruber;Beth A. Schodin;Erik R. Wilson;David M. Kranz;David M. Kranz

359
Citations
Directed evolution of a stable scaffold for T-cell receptor engineering

E V Shusta;P D Holler;M C Kieke;D M Kranz

330
Citations
Yeast polypeptide fusion surface display levels predict thermal stability and soluble secretion efficiency.

Eric V Shusta;Michele C Kieke;Evan Parke;David M Kranz

320
Citations
How a Single T Cell Receptor Recognizes Both Self and Foreign MHC

Leremy A. Colf;Alexander J. Bankovich;Nicole A. Hanick;Natalie A. Bowerman

297
Citations

Frequent Co-Authors

Herman N. Eisen MIT

Susumu Tonegawa MIT

Eric V. Shusta University of Wisconsin–Madison

Hans Schreiber University of Chicago

Anant Agarwal MIT

K. Dane Wittrup MIT

Philip D. Greenberg Fred Hutchinson Cancer Research Center

K. Christopher Garcia Stanford University

Roy A. Mariuzza University of Maryland, College Park

Patrick M. Schlievert University of Iowa

External Links

Personal website of David M. Kranz

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