What is he best known for?
The fields of study he is best known for:
His primary areas of investigation include Molecular biology, T-cell receptor, T cell, Antigen and Major histocompatibility complex.
His Molecular biology research incorporates themes from CTL*, Cytotoxic T cell, CD8, Gene and Antibody.
His studies deal with areas such as Yeast display, Peptide sequence, Cell biology, Clone and Peptide as well as T-cell receptor.
A large part of his T cell studies is devoted to MHC restriction.
The study incorporates disciplines such as Protein structure and Transfection in addition to Antigen.
His research integrates issues of Complementarity determining region and Docking in his study of Major histocompatibility complex.
His most cited work include:
- Positive and negative selection of an antigen receptor on T cells in transgenic mice (675 citations)
- Host type I IFN signals are required for antitumor CD8+ T cell responses through CD8α+ dendritic cells (657 citations)
- Complete primary structure of a heterodimeric T-cell receptor deduced from cDNA sequences. (549 citations)
What are the main themes of his work throughout his whole career to date?
His primary scientific interests are in T-cell receptor, Molecular biology, Major histocompatibility complex, T cell and Antigen.
He has researched T-cell receptor in several fields, including Receptor, CD8, Peptide and Cell biology.
The concepts of his Cell biology study are interwoven with issues in Superantigen and Affinity maturation.
His studies examine the connections between Molecular biology and genetics, as well as such issues in Cytotoxic T cell, with regards to Clone.
His Major histocompatibility complex study incorporates themes from Complementarity determining region, Peptide sequence and Yeast display.
His Antigen study integrates concerns from other disciplines, such as Cell culture and Immune system.
He most often published in these fields:
- T-cell receptor (66.98%)
- Molecular biology (50.78%)
- Major histocompatibility complex (40.50%)
What were the highlights of his more recent work (between 2012-2020)?
- T-cell receptor (66.98%)
- T cell (38.94%)
- Antigen (31.46%)
In recent papers he was focusing on the following fields of study:
His scientific interests lie mostly in T-cell receptor, T cell, Antigen, Major histocompatibility complex and Cell biology.
His T-cell receptor research includes elements of Cytotoxic T cell, Receptor, Peptide and Directed evolution.
His work focuses on many connections between T cell and other disciplines, such as Gene, that overlap with his field of interest in In vivo and Transmembrane protein.
Antigen is a subfield of Immunology that David M. Kranz explores.
His work carried out in the field of Major histocompatibility complex brings together such families of science as Protein structure and Complementarity determining region.
Within one scientific family, he focuses on topics pertaining to Yeast display under Cell biology, and may sometimes address concerns connected to Affinity maturation and Microbiology.
Between 2012 and 2020, his most popular works were:
- Engineered CAR T Cells Targeting the Cancer-Associated Tn-Glycoform of the Membrane Mucin MUC1 Control Adenocarcinoma. (264 citations)
- Engineering human ACE2 to optimize binding to the spike protein of SARS coronavirus 2. (133 citations)
- Adoptive T Cell Therapies: A Comparison of T Cell Receptors and Chimeric Antigen Receptors (112 citations)
In his most recent research, the most cited papers focused on:
His primary scientific interests are in T-cell receptor, Immunology, Cell biology, Antigen and T cell.
His study in T-cell receptor is interdisciplinary in nature, drawing from both Cytotoxic T cell and Major histocompatibility complex.
His Major histocompatibility complex research is multidisciplinary, relying on both Protein structure and Peptide.
His work deals with themes such as Cancer, Cancer research and Disease, which intersect with Immunology.
His study looks at the intersection of Cell biology and topics like Receptor with Genetically modified organism, Function and Binding site.
His research in T cell intersects with topics in CD8 and Immunotherapy.
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