What is he best known for?
The fields of study he is best known for:
His primary areas of study are T-cell receptor, Epitope, CD8, Antigen and T cell.
His T-cell receptor study integrates concerns from other disciplines, such as Molecular biology, Biophysics and MHC class I, Major histocompatibility complex.
The concepts of his Epitope study are interwoven with issues in Human leukocyte antigen, CTL* and Avidity.
His CTL* research includes themes of Tetramer and Virology.
His work in Antigen addresses subjects such as Receptor, which are connected to disciplines such as Transplantation and Phage display.
His work on CD28 as part of general T cell study is frequently connected to Dasatinib, therefore bridging the gap between diverse disciplines of science and establishing a new relationship between them.
His most cited work include:
- POSITIVE SELECTION OF HIV-1 CYTOTOXIC T LYMPHOCYTE ESCAPE VARIANTS DURING PRIMARY INFECTION (644 citations)
- Early highly active antiretroviral therapy for acute HIV-1 infection preserves immune function of CD8+ and CD4+ T lymphocytes (357 citations)
- Avidity for antigen shapes clonal dominance in CD8 + T cell populations specific for persistent DNA viruses (335 citations)
What are the main themes of his work throughout his whole career to date?
Andrew K. Sewell mainly focuses on T-cell receptor, T cell, Antigen, CD8 and Immunology.
The T-cell receptor study combines topics in areas such as Molecular biology, Receptor, Cell biology, Epitope and Major histocompatibility complex.
His T cell research is multidisciplinary, incorporating elements of Cancer research, Antibody and Flow cytometry.
His research in Antigen intersects with topics in Computational biology and Immunotherapy.
His CD8 research is multidisciplinary, incorporating perspectives in Tetramer, Avidity and Effector.
He interconnects Cancer and Type 1 diabetes in the investigation of issues within Immunology.
He most often published in these fields:
- T-cell receptor (59.34%)
- T cell (45.23%)
- Antigen (43.98%)
What were the highlights of his more recent work (between 2017-2021)?
- T-cell receptor (59.34%)
- T cell (45.23%)
- Antigen (43.98%)
In recent papers he was focusing on the following fields of study:
Andrew K. Sewell mostly deals with T-cell receptor, T cell, Antigen, Epitope and Immune system.
The various areas that Andrew K. Sewell examines in his T-cell receptor study include Human leukocyte antigen, Cancer immunotherapy, Peptide and Cell biology.
His T cell research integrates issues from Cancer research, MHC class I, CD8, Virus and Antibody.
The study incorporates disciplines such as Effector and Virology in addition to CD8.
His research in the fields of Major histocompatibility complex overlaps with other disciplines such as Context.
His Epitope study combines topics in areas such as Molecular biology, Influenza A virus, Antigen presentation and Immunogenicity.
Between 2017 and 2021, his most popular works were:
- VDJdb: a curated database of T-cell receptor sequences with known antigen specificity (164 citations)
- CRISPR-mediated TCR replacement generates superior anticancer transgenic T cells (91 citations)
- Genome-wide CRISPR–Cas9 screening reveals ubiquitous T cell cancer targeting via the monomorphic MHC class I-related protein MR1 (74 citations)
In his most recent research, the most cited papers focused on:
Andrew K. Sewell spends much of his time researching T-cell receptor, T cell, Antigen, Epitope and Major histocompatibility complex.
His studies in T-cell receptor integrate themes in fields like Complementarity determining region and Sequence analysis.
His T cell research includes elements of MHC class I and CD8.
His research integrates issues of T-Cell Antigen Receptor Specificity, Virology, Immunodominance and Cell biology in his study of CD8.
His studies deal with areas such as Receptor, Computational biology and Molecular Sequence Annotation as well as Antigen.
Andrew K. Sewell has included themes like Combinatorial chemistry, Synthetic biology and Immunogenicity in his Epitope study.
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