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Immunology

D-Index
70
Citations
19208
World Ranking
2398
National Ranking
210

Overview

Emma Gostick is affiliated with Cardiff University in the United Kingdom. Their research primarily focuses on immunology, with a significant emphasis on the behavior and characteristics of CD8+ T cells, especially in the context of infectious diseases and immune response mechanisms.

Their published works span multiple topics within immunology and related medical fields, including immune cell function and interaction, T-cell and B-cell immunology, immunotherapy and immune responses, and hepatitis virus research.

Some of the recent papers by Emma Gostick include:

  • "Two subsets of stem-like CD8+ memory T cell progenitors with distinct fate commitments in humans," 2020, Nature Immunology
  • "TOX is expressed by exhausted and polyfunctional human effector memory CD8+ T cells," 2020, Science Immunology
  • "Memory-like HCV-specific CD8+ T cells retain a molecular scar after cure of chronic HCV infection," 2021, Nature Immunology
  • "The Identity of Human Tissue-Emigrant CD8+ T Cells," 2020, Cell
  • "Extended clinical and immunological phenotype and transplant outcome in CD27 and CD70 deficiency," 2020, Blood

Emma Gostick frequently publishes in journals such as Nature Immunology, bioRxiv (Cold Spring Harbor Laboratory), Zeitschrift für Gastroenterologie, Science Immunology, and Cell.

  • Nature Immunology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Zeitschrift für Gastroenterologie
  • Science Immunology
  • Cell

In collaboration, Emma Gostick often works with researchers including:

  • David A. Price
  • Sian Llewellyn-Lacey
  • Christoph Neumann-Haefelin
  • Robert Thimme
  • Maike Hofmann

Emma Gostick's studies contribute to fields such as immunology and microbiology and medicine, with subfields in immunology, epidemiology, hepatology, oncology, and genetics. Their key research topics consist of:

  • Immune Cell Function and Interaction
  • T-cell and B-cell Immunology
  • Immunotherapy and Immune Responses
  • Hepatitis C virus research
  • Hepatitis B Virus Studies
  • CAR-T cell therapy research
  • Diabetes and associated disorders

Best Publications

  • A human memory T cell subset with stem cell-like properties

    Luca Gattinoni;Enrico Lugli;Yun Ji;Zoltan Pos

  • PD-1 is a regulator of virus-specific CD8+ T cell survival in HIV infection.

    Constantinos Petrovas;Joseph P. Casazza;Jason M. Brenchley;David A. Price

  • Monoclonal TCR-redirected tumor cell killing

    Nathaniel Liddy;Giovanna Bossi;Katherine J. Adams;Anna Lissina

  • Immunization with vaccinia virus induces polyfunctional and phenotypically distinctive CD8+ T cell responses

    Melissa L. Precopio;Michael R. Betts;Janie Parrino;David A. Price

  • Quantum dot semiconductor nanocrystals for immunophenotyping by polychromatic flow cytometry

    Pratip K Chattopadhyay;David A Price;Theresa F Harper;Michael R Betts;Michael R Betts

  • Synergistic Reversal of Intrahepatic HCV-Specific CD8 T Cell Exhaustion by Combined PD-1/CTLA-4 Blockade

    Nobuhiro Nakamoto;Hyosun Cho;Hyosun Cho;Abraham Shaked;Kim Olthoff

  • Avidity for antigen shapes clonal dominance in CD8 + T cell populations specific for persistent DNA viruses

    David A. Price;Jason M. Brenchley;Laura E. Ruff;Michael R. Betts

  • Induction of complete and molecular remissions in acute myeloid leukemia by Wilms’ tumor 1 antigen-targeted dendritic cell vaccination

    Viggo F. van Tendeloo;Ann Van de Velde;Ann van Driessche;Nathalie Cools

  • Butyrophilin 3A1 binds phosphorylated antigens and stimulates human γδ T cells.

    Stefano Vavassori;Anil Kumar;Gan S Wan;Gundimeda S Ramanjaneyulu

  • Immunodominance and functional alterations of tumor‐associated antigen‐specific CD8+ T‐cell responses in hepatocellular carcinoma

    Tobias Flecken;Nathalie Schmidt;Sandra Hild;Emma Gostick

  • Superior T memory stem cell persistence supports long-lived T cell memory

    Enrico Lugli;Maria H. Dominguez;Luca Gattinoni;Pratip K. Chattopadhyay

  • Functional restoration of HCV-specific CD8 T cells by PD-1 blockade is defined by PD-1 expression and compartmentalization

    Nobuhiro Nakamoto;Nobuhiro Nakamoto;David E. Kaplan;David E. Kaplan;Jennifer Coleclough;Jennifer Coleclough;Yun Li;Yun Li

  • Functional leukemia-associated antigen-specific memory CD8+ T cells exist in healthy individuals and in patients with chronic myelogenous leukemia before and after stem cell transplantation.

    Katayoun Rezvani;Matthias Grube;Matthias Grube;Jason M. Brenchley;Jason M. Brenchley;Giuseppe Sconocchia;Giuseppe Sconocchia

  • The cytolytic enzymes granyzme A, granzyme B, and perforin: expression patterns, cell distribution, and their relationship to cell maturity and bright CD57 expression.

    Pratip K. Chattopadhyay;Michael R. Betts;David A. Price;Emma Gostick

  • Two subsets of stem-like CD8+ memory T cell progenitors with distinct fate commitments in humans.

    Giovanni Galletti;Gabriele De Simone;Emilia M C Mazza;Simone Puccio

  • Different T Cell Receptor Affinity Thresholds and CD8 Coreceptor Dependence Govern Cytotoxic T Lymphocyte Activation and Tetramer Binding Properties

    Bruno Frederic Laugel;Hugo A. van den Berg;Emma Gostick;David Cole

  • Human TCR-binding affinity is governed by MHC class restriction.

    David K. Cole;Nicholas J. Pumphrey;Jonathan M. Boulter;Malkit Sami

  • Graft-versus-leukemia effects associated with detectable Wilms tumor-1-specific T lymphocytes after allogeneic stem-cell transplantation for acute lymphoblastic leukemia

    Katayoun Rezvani;Agnes S. M. Yong;Bipin N. Savani;Stephan Mielke

  • Structural basis for the killing of human beta cells by CD8(+) T cells in type 1 diabetes.

    Anna Marta Bulek;David Cole;Ania Skowera;Ania Skowera;Garry Michael Dolton

  • Surface expression patterns of negative regulatory molecules identify determinants of virus-specific CD8+ T-cell exhaustion in HIV infection

    Takuya Yamamoto;David A. Price;David A. Price;Joseph P. Casazza;Guido Ferrari

  • SIV-specific CD8+ T cells express high levels of PD1 and cytokines but have impaired proliferative capacity in acute and chronic SIVmac251 infection

    Constantinos Petrovas;David A. Price;David A. Price;Joseph Mattapallil;David R. Ambrozak

Frequent Co-Authors

David Price
David Price University of Aberdeen
Daniel C. Douek
Daniel C. Douek National Institute of Allergy and Infectious Diseases
Andrew K. Sewell
Andrew K. Sewell Cardiff University
Kristin Ladell
Kristin Ladell Cardiff University
Jamie Rossjohn
Jamie Rossjohn Monash University
John J. Miles
John J. Miles James Cook University
Mario Roederer
Mario Roederer National Institute of Allergy and Infectious Diseases
A. John Barrett
A. John Barrett National Institutes of Health
J. Joseph Melenhorst
J. Joseph Melenhorst University of Pennsylvania
Michael R. Betts
Michael R. Betts University of Pennsylvania

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