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Medicine
Switzerland
2023
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Immunology
Switzerland
2022

D-Index & Metrics

Immunology

D-Index
106
Citations
41576
World Ranking
566
National Ranking
13

Medicine

D-Index
106
Citations
41574
World Ranking
6537
National Ranking
89

Research.com Recognitions

  • 2023 - Research.com Medicine in Switzerland Leader Award
  • 2022 - Research.com Immunology in Switzerland Leader Award

Overview

Daniel E. Speiser is affiliated with the University of Lausanne in Switzerland and has an extensive publication record in the fields of Medicine and Immunology and Microbiology.

Their research primarily focuses on areas within Immunology and Oncology, with notable work in Molecular Biology, Infectious Diseases, and Epidemiology as well.

Main topics covered by their work include:

  • Immunotherapy and Immune Responses
  • CAR-T cell therapy research
  • Cancer Immunotherapy and Biomarkers
  • Immune Cell Function and Interaction
  • T-cell and B-cell Immunology
  • Vaccines and immunoinformatics approaches
  • SARS-CoV-2 and COVID-19 Research

Frequent coauthors collaborating with Daniel E. Speiser are:

  • Martin F. Bachmann
  • Mona O. Mohsen
  • George Coukos
  • Alexandre Harari
  • Julien Schmidt

They have published notably in several scientific journals, with frequent venues including:

  • Cancer Cell
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Nature Cancer
  • Vaccines

Among the recent papers authored or co-authored by Daniel E. Speiser are the following:

  • "CD4+ T cells in cancer", 2023, Nature Cancer
  • "Conserved Interferon-γ Signaling Drives Clinical Response to Immune Checkpoint Blockade Therapy in Melanoma", 2020, Cancer Cell
  • "Tumor-specific cytolytic CD4 T cells mediate immunity against human cancer", 2021, Science Advances
  • "The commensal skin microbiota triggers type I IFN-dependent innate repair responses in injured skin", 2020, Nature Immunology
  • "Central memory CD8+ T cells derive from stem-like Tcf7hi effector cells in the absence of cytotoxic differentiation", 2020, Immunity

Daniel E. Speiser's body of work spans basic and clinical research in immunology and cancer biology, particularly emphasizing immune cell functionality, immune checkpoint therapies, and T cell-based interventions.

Best Publications

  • Intratumoral Tcf1+PD-1+CD8+ T Cells with Stem-like Properties Promote Tumor Control in Response to Vaccination and Checkpoint Blockade Immunotherapy.

    Imran Siddiqui;Karin Schaeuble;Vijaykumar Chennupati;Silvia A. Fuertes Marraco

  • Defining ‘T cell exhaustion’

    Christian U Blank;W Nicholas Haining;Werner Held;Patrick G Hogan;Patrick G Hogan

  • Simultaneous enumeration of cancer and immune cell types from bulk tumor gene expression data.

    Julien Racle;Julien Racle;Kaat de Jonge;Petra Baumgaertner;Daniel E Speiser

  • Early Lethality, Functional NF-κB Activation, and Increased Sensitivity to TNF-Induced Cell Death in TRAF2-Deficient Mice

    Wen-Chen Yeh;Arda Shahinian;Daniel I Speiser;Janine Kraunus

  • Exhaustion of tumor-specific CD8(+) T cells in metastases from melanoma patients

    Lukas Baitsch;Petra Baumgaertner;Estelle Devêvre;Sunil K. Raghav

  • Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition)

    Andrea Cossarizza;Hyun Dong Chang;Andreas Radbruch;Andreas Acs

  • Rapid and strong human CD8 + T cell responses to vaccination with peptide, IFA, and CpG oligodeoxynucleotide 7909

    Daniel E. Speiser;Danielle Liénard;Nathalie Rufer;Verena Rubio-Godoy

  • High Frequencies of Naive Melan-a/Mart-1–Specific Cd8+ T Cells in a Large Proportion of Human Histocompatibility Leukocyte Antigen (Hla)-A2 Individuals

    M J Pittet;D Valmori;P R Dunbar;D E Speiser

  • Ipilimumab-dependent cell-mediated cytotoxicity of regulatory T cells ex vivo by nonclassical monocytes in melanoma patients

    Emanuela Romano;Monika Kusio-Kobialka;Periklis G. Foukas;Petra Baumgaertner

  • Frequencies of circulating MDSC correlate with clinical outcome of melanoma patients treated with ipilimumab

    Christiane Meyer;Laurène Cagnon;Carla M. Costa-Nunes;Petra Baumgaertner

  • Regulatory circuits of T cell function in cancer

    Daniel E. Speiser;Ping-Chih Ho;Grégory Verdeil

  • Classification of current anticancer immunotherapies

    Lorenzo Galluzzi;Erika Vacchelli;José Manuel Bravo-San Pedro;Aitziber Buqué

  • STING activation of tumor endothelial cells initiates spontaneous and therapeutic antitumor immunity

    Olivier Demaria;Aude De Gassart;Sanja Coso;Nicolas Gestermann

  • T memory stem cells in health and disease

    Luca Gattinoni;Daniel E Speiser;Mathias Lichterfeld;Chiara Bonini

  • Distinct roles for LFA-1 and CD28 during activation of naive T cells: adhesion versus costimulation

    Martin F Bachmann;Kim McKall-Faienza;Rudolf Schmits;Rudolf Schmits;Denis Bouchard

  • Decreased specific CD8+ T cell cross‐reactivity of antigen recognition following vaccination with Melan‐A peptide

    Victor Appay;Victor Appay;Daniel E. Speiser;Nathalie Rufer;Severine Reynard

  • Four functionally distinct populations of human effector-memory CD8+ T lymphocytes.

    Pedro Romero;Alfred Zippelius;Alfred Zippelius;Isabel Kurth;Mikaël J. Pittet;Mikaël J. Pittet

  • Exome sequencing identifies recurrent somatic MAP2K1 and MAP2K2 mutations in melanoma

    Sergey Igorievich Nikolaev;Donata Rimoldi;Christian Iseli;Christian Iseli;Armand Valsesia;Armand Valsesia;Armand Valsesia

  • Increased Numbers of Circulating Polyfunctional Th17 Memory Cells in Patients With Seronegative Spondylarthritides

    Camilla Jandus;Gilles Bioley;Jean-Paul Rivals;Jean Dudler

  • Effector Function of Human Tumor-Specific CD8 T Cells in Melanoma Lesions: A State of Local Functional Tolerance

    Alfred Zippelius;Pascal Batard;Verena Rubio-Godoy;Gilles Bioley

Frequent Co-Authors

Pedro Romero
Pedro Romero University of Lausanne
Jean-Charles Cerottini
Jean-Charles Cerottini University of Lausanne
Nathalie Rufer
Nathalie Rufer University Hospital of Lausanne
Olivier Michielin
Olivier Michielin University of Lausanne
Philippe Guillaume
Philippe Guillaume University of Lausanne
Danila Valmori
Danila Valmori University of Nantes
Martin F. Bachmann
Martin F. Bachmann University of Bern
Mikael J. Pittet
Mikael J. Pittet University of Geneva
Pamela S. Ohashi
Pamela S. Ohashi Princess Margaret Cancer Centre
Alfred Zippelius
Alfred Zippelius University Hospital of Basel

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