Nathalie Rufer

Overview

Best Publications

• Exhaustion of tumor-specific CD8(+) T cells in metastases from melanoma patients

  Lukas Baitsch;Petra Baumgaertner;Estelle Devêvre;Sunil K. Raghav

  940
  Citations

• Infusion of cytomegalovirus (CMV)-specific T cells for the treatment of CMV infection not responding to antiviral chemotherapy.

  Hermann Einsele;Eddy Roosnek;Nathalie Rufer;Christian Sinzger

  914
  Citations

• Telomere Fluorescence Measurements in Granulocytes and T Lymphocyte Subsets Point to a High Turnover of Hematopoietic Stem Cells and Memory T Cells in Early Childhood

  Nathalie Rufer;Tim H. Brümmendorf;Steen Kolvraa;Claus Bischoff

  836
  Citations

• Rapid and strong human CD8 + T cell responses to vaccination with peptide, IFA, and CpG oligodeoxynucleotide 7909

  Daniel E. Speiser;Danielle Liénard;Nathalie Rufer;Verena Rubio-Godoy

  769
  Citations

• Telomere length dynamics in human lymphocyte subpopulations measured by flow cytometry.

  Nathalie Rufer;Wieslawa Dragowska;Gayle Thornbury;Eddy Roosnek

  747
  Citations

• Immune Activation and CD8+ T-Cell Differentiation towards Senescence in HIV-1 Infection

  L Papagno;C A Spina;A Marchant;M Salio

  575
  Citations

• Decreased specific CD8+ T cell cross‐reactivity of antigen recognition following vaccination with Melan‐A peptide

  Victor Appay;Victor Appay;Daniel E. Speiser;Nathalie Rufer;Severine Reynard

  510
  Citations

• Four functionally distinct populations of human effector-memory CD8+ T lymphocytes.

  Pedro Romero;Alfred Zippelius;Alfred Zippelius;Isabel Kurth;Mikaël J. Pittet;Mikaël J. Pittet

  508
  Citations

• Effector Function of Human Tumor-Specific CD8 T Cells in Melanoma Lesions: A State of Local Functional Tolerance

  Alfred Zippelius;Pascal Batard;Verena Rubio-Godoy;Gilles Bioley

  453
  Citations

• MicroRNA-155 Is Required for Effector CD8+ T Cell Responses to Virus Infection and Cancer

  Jan C. Dudda;Bruno Salaun;Yun Ji;Douglas C. Palmer

  365
  Citations

• The proteolytic activity of the paracaspase MALT1 is key in T cell activation.

  Fabien Rebeaud;Stephan Hailfinger;Anita Posevitz-Fejfar;Myriam Tapernoux

  339
  Citations

• Evidence for a TCR Affinity Threshold Delimiting Maximal CD8 T Cell Function

  Daphné A. Schmid;Melita B. Irving;Vilmos Posevitz;Michael Hebeisen

  301
  Citations

• Transfer of the human telomerase reverse transcriptase(TERT) gene into T lymphocytes results in extension of replicative potential

  Nathalie Rufer;Marco Migliaccio;Jennifer Antonchuk;R. Keith Humphries

  264
  Citations

• Extended co-expression of inhibitory receptors by human CD8 T-cells depending on differentiation, antigen-specificity and anatomical localization.

  Lukas Baitsch;Amandine Legat;Leticia Barba;Silvia A. Fuertes Marraco

  244
  Citations

• Ex vivo characterization of human CD8+ T subsets with distinct replicative history and partial effector functions.

  Nathalie Rufer;Alfred Zippelius;Pascal Batard;Mikaël J. Pittet

  223
  Citations

• Long-lasting stem cell–like memory CD8+ T cells with a naïve-like profile upon yellow fever vaccination

  Silvia A. Fuertes Marraco;Silvia A. Fuertes Marraco;Charlotte Soneson;Laurène Cagnon;Philippe O. Gannon

  222
  Citations

• Antigenicity and immunogenicity of Melan-A/MART-1 derived peptides as targets for tumor reactive CTL in human melanoma.

  Pedro Romero;Danila Valmori;Mikael J. Pittet;Alfred Zippelius

  210
  Citations

• Thymic selection generates a large T cell pool recognizing a self-peptide in humans.

  Alfred Zippelius;Mikaël J. Pittet;Pascal Batard;Nathalie Rufer

  200
  Citations

• High resolution HLA matching associated with decreased mortality after unrelated bone marrow transplantation.

  Daniel E. Speiser;Jean-Marie Tiercy;Nathalie Rufer;Christophe Grundschober

  195
  Citations

• New generation vaccine induces effective melanoma-specific CD8+ T cells in the circulation but not in the tumor site.

  Victor Appay;Camilla Jandus;Verena Voelter;Severine Reynard

  193
  Citations

• Unmodified self antigen triggers human CD8 T cells with stronger tumor reactivity than altered antigen

  Daniel E. Speiser;Petra Baumgaertner;Verena Voelter;Estelle Devevre

  188
  Citations

• Interplay between T Cell Receptor Binding Kinetics and the Level of Cognate Peptide Presented by Major Histocompatibility Complexes Governs CD8+ T Cell Responsiveness

  Melita Irving;Vincent Zoete;Michael Hebeisen;Daphné Schmid

  175
  Citations