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Immunology

D-Index
58
Citations
11963
World Ranking
3524
National Ranking
84

Overview

Alexandre Harari is affiliated with the University of Lausanne in Switzerland. Their research spans multiple interconnected fields, primarily focusing on Medicine, Immunology and Microbiology, and Biochemistry, Genetics and Molecular Biology. Within these areas, Harari's work touches on subfields such as Immunology, Oncology, Molecular Biology, Radiology, Nuclear Medicine and Imaging, and Genetics.

The main themes of Harari's research include Immunotherapy and Immune Responses, CAR-T cell therapy research, Cancer Immunotherapy and Biomarkers, vaccines and immunoinformatics approaches, T-cell and B-cell Immunology, Immune Cell Function and Interaction, and Monoclonal and Polyclonal Antibodies Research.

Harari has co-authored extensively with several researchers, including George Coukos, Sara Bobisse, Lana E. Kandalaft, Raphaël Genolet, and Michal Bassani-Sternberg. These collaborations account for many of their joint publications and contributions to advancing immunology and cancer research.

The most frequent venues publishing Harari's work include bioRxiv (Cold Spring Harbor Laboratory), Frontiers in Immunology, Nature Communications, Nature Biotechnology, and Science Advances.

Key recent publications by Harari encompass the following:

  • Antitumour dendritic cell vaccination in a priming and boosting approach, 2020, Nature Reviews Drug Discovery
  • Integrated proteogenomic deep sequencing and analytics accurately identify non-canonical peptides in tumor immunopeptidomes, 2020, Nature Communications
  • Tumor-specific cytolytic CD4 T cells mediate immunity against human cancer, 2021, Science Advances
  • T-cell repertoire analysis and metrics of diversity and clonality, 2020, Current Opinion in Biotechnology
  • Prediction of neo-epitope immunogenicity reveals TCR recognition determinants and provides insight into immunoediting, 2021, Cell Reports Medicine

Best Publications

  • Immunization with vaccinia virus induces polyfunctional and phenotypically distinctive CD8+ T cell responses

    Melissa L. Precopio;Michael R. Betts;Janie Parrino;David A. Price

  • Dominant TNF-α + Mycobacterium tuberculosis –specific CD4 + T cell responses discriminate between latent infection and active disease

    Alexandre Harari;Virginie Rozot;Felicitas Bellutti Enders;Matthieu Perreau

  • Skewed representation of functionally distinct populations of virus-specific CD4 T cells in HIV-1-infected subjects with progressive disease: changes after antiretroviral therapy.

    Alexandre Harari;Stéphanie Petitpierre;Florence Vallelian;Giuseppe Pantaleo

  • Personalized cancer vaccine effectively mobilizes antitumor T cell immunity in ovarian cancer

    Janos L. Tanyi;Sara Bobisse;Eran Ophir;Sandra Tuyaerts

  • HIV-1-specific IFN-γ/IL-2-secreting CD8 T cells support CD4-independent proliferation of HIV-1-specific CD8 T cells

    Simone C. Zimmerli;Alexandre Harari;Cristina Cellerai;Florence Vallelian

  • An HIV-1 clade C DNA prime, NYVAC boost vaccine regimen induces reliable, polyfunctional, and long-lasting T cell responses.

    Alexandre Harari;Pierre-Alexandre Bart;Wolfgang Stöhr;Gonzalo Tapia

  • Functional Heterogeneity of Memory CD4 T Cell Responses in Different Conditions of Antigen Exposure and Persistence

    Alexandre Harari;Florence Vallelian;Pascal R. Meylan;Giuseppe Pantaleo

  • Functional signatures of protective antiviral T-cell immunity in human virus infections

    Alexandre Harari;Valérie Dutoit;Cristina Cellerai;Pierre‐Alexandre Bart

  • Integrated proteogenomic deep sequencing and analytics accurately identify non-canonical peptides in tumor immunopeptidomes.

    Chloe Chong;Chloe Chong;Markus Müller;HuiSong Pak;HuiSong Pak;Dermot Harnett

  • Tumor-specific cytolytic CD4 T cells mediate immunity against human cancer

    Amélie Cachot;Mariia Bilous;Mariia Bilous;Yen-Cheng Liu;Xiaokang Li

  • Robust prediction of HLA class II epitopes by deep motif deconvolution of immunopeptidomes.

    Julien Racle;Justine Michaux;Georg Alexander Rockinger;Marion Arnaud

  • Standardization of cytokine flow cytometry assays

    Holden T Maecker;Aline Rinfret;Patricia D'Souza;Janice Darden

  • Tuberculosis Diagnostics and Biomarkers: Needs, Challenges, Recent Advances, and Opportunities

    Ruth McNerney;Markus Maeurer;Ibrahim Abubakar;Ibrahim Abubakar;Ben Marais

  • Novel technologies and emerging biomarkers for personalized cancer immunotherapy.

    Jianda Yuan;Priti S. Hegde;Raphael Clynes;Periklis G. Foukas;Periklis G. Foukas

  • Functional signatures in antiviral T-cell immunity for monitoring virus-associated diseases.

    Giuseppe Pantaleo;Alexandre Harari

  • Antitumour dendritic cell vaccination in a priming and boosting approach

    Alexandre Harari;Alexandre Harari;Michele Graciotti;Michele Graciotti;Michal Bassani-Sternberg;Michal Bassani-Sternberg;Lana E Kandalaft;Lana E Kandalaft

  • Mycobacterium Tuberculosis-Specific CD8+ T Cells Are Functionally and Phenotypically Different Between Latent Infection and Active Disease

    Virginie Rozot;Selena Vigano;Jesica Mazza-Stalder;Elita Idrizi

  • Phenotypic heterogeneity of antigen‐specific CD4 T cells under different conditions of antigen persistence and antigen load

    Alexandre Harari;Florence Vallelian;Giuseppe Pantaleo

  • Treatment of primary HIV-1 infection with cyclosporin A coupled with highly active antiretroviral therapy

    G. Paolo Rizzardi;Alexandre Harari;Brunella Capiluppi;Giuseppe Tambussi

  • Adenosine mediates functional and metabolic suppression of peripheral and tumor-infiltrating CD8+ T cells

    Beatris Mastelic-Gavillet;Blanca Navarro Rodrigo;Laure Décombaz;Haiping Wang

  • Low Dose Radiotherapy Reverses Tumor Immune Desertification and Resistance to Immunotherapy.

    Fernanda G Herrera;Catherine Ronet;Maria Ochoa de Olza;David Barras

Frequent Co-Authors

Giuseppe Pantaleo
Giuseppe Pantaleo University of Lausanne
George Coukos
George Coukos Cornell University
Lana E. Kandalaft
Lana E. Kandalaft Ludwig Cancer Research
David Gfeller
David Gfeller University of Lausanne
Michal Bassani-Sternberg
Michal Bassani-Sternberg Ludwig Cancer Research
Philippe Guillaume
Philippe Guillaume University of Lausanne
Daniel E. Speiser
Daniel E. Speiser University of Lausanne
Ralf Wagner
Ralf Wagner University of Regensburg
Brian Stevenson
Brian Stevenson University of Kentucky
Thierry Calandra
Thierry Calandra University of Lausanne

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