World's Best Scientists 2026 revealed!

D-Index & Metrics

Immunology

D-Index
88
Citations
24989
World Ranking
1178
National Ranking
104

Medicine

D-Index
88
Citations
24994
World Ranking
13277
National Ranking
1238

Research.com Recognitions

  • Fellow of the Royal Society of South Africa
  • Fellow of the Royal Society of South Africa
  • Fellow of the Royal Society of South Africa
  • Fellow of the Royal Society of South Africa

Overview

Willem A. Hanekom is affiliated with University College London in the United Kingdom. Their research primarily focuses on medicine, with a substantial body of work in immunology and microbiology. Within these domains, their contributions emphasize infectious diseases, immunology, and epidemiology, alongside work relevant to general health professions and surgery.

The scientist's research topics include:

  • Tuberculosis Research and Epidemiology
  • SARS-CoV-2 and COVID-19 Research
  • Immune responses and vaccinations
  • COVID-19 Clinical Research Studies
  • Immunodeficiency and Autoimmune Disorders
  • HIV/AIDS Impact and Responses
  • HIV/AIDS Research and Interventions

Recent notable papers authored by Hanekom include:

  • "Omicron extensively but incompletely escapes Pfizer BNT162b2 neutralization" (2021, Nature)
  • "Escape of SARS-CoV-2 501Y.V2 from neutralization by convalescent plasma" (2021, Nature)
  • "SARS-CoV-2 Omicron has extensive but incomplete escape of Pfizer BNT162b2 elicited neutralization and requires ACE2 for infection" (2021, bioRxiv (Cold Spring Harbor Laboratory))
  • "SARS-CoV-2 prolonged infection during advanced HIV disease evolves extensive immune escape" (2022, Cell Host & Microbe)
  • "Omicron extensively but incompletely escapes Pfizer BNT162b2 neutralization" (2021, Nature)

Frequent co-authors in their research include:

  • Emily Wong
  • Khadija Khan
  • Alex Sigal
  • Thumbi Ndung'u
  • Farina Karim

The researcher has published extensively in various venues, most commonly in:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Frontiers in Immunology
  • Nature
  • Nature Communications
  • Wellcome Open Research

Willem A. Hanekom has received recognition as a Fellow of the Royal Society of South Africa. Their body of work spans over 160 publications in medicine and around 55 in immunology and microbiology, reflecting sustained engagement with infectious diseases and immune response research.

Best Publications

  • Safety and efficacy of MVA85A, a new tuberculosis vaccine, in infants previously vaccinated with BCG: a randomised, placebo-controlled phase 2b trial

    Michele D Tameris;Mark Hatherill;Bernard S Landry;Thomas J Scriba

  • A blood RNA signature for tuberculosis disease risk: a prospective cohort study.

    Daniel E Zak;Adam Penn-Nicholson;Thomas J Scriba;Ethan Thompson

  • Prevention of M. tuberculosis Infection with H4:IC31 Vaccine or BCG Revaccination

    Elisa Nemes;Hennie Geldenhuys;Virginie Rozot;Kathryn T Rutkowski

  • Escape of SARS-CoV-2 501Y.V2 from neutralization by convalescent plasma.

    Sandile Cele;Inbal Gazy;Inbal Gazy;Laurelle Jackson;Shi-Hsia Hwa

  • Immunological biomarkers of tuberculosis.

    Gerhard Walzl;Katharina Ronacher;Willem Hanekom;Thomas J. Scriba

  • SARS-CoV-2 Omicron has extensive but incomplete escape of Pfizer BNT162b2 elicited neutralization and requires ACE2 for infection

    Unknown

  • Distinct, Specific IL-17- and IL-22-Producing CD4+ T Cell Subsets Contribute to the Human Anti-Mycobacterial Immune Response

    Thomas J. Scriba;Barbara Kalsdorf;Deborah-Ann Abrahams;Fatima Isaacs

  • Specific T Cell Frequency and Cytokine Expression Profile Do Not Correlate with Protection against Tuberculosis after Bacillus Calmette-Guérin Vaccination of Newborns

    Benjamin M. N. Kagina;Brian Abel;Thomas J. Scriba;Elizabeth J. Hughes

  • Dominant TNF-α + Mycobacterium tuberculosis –specific CD4 + T cell responses discriminate between latent infection and active disease

    Alexandre Harari;Virginie Rozot;Felicitas Bellutti Enders;Matthieu Perreau

  • Functional capacity of Mycobacterium tuberculosis-specific T cell responses in humans is associated with mycobacterial load

    Cheryl L. Day;Cheryl L. Day;Deborah A. Abrahams;Lesedi Lerumo;Esme Janse van Rensburg

  • T cells and adaptive immunity to Mycobacterium tuberculosis in humans

    Luke D. Jasenosky;Thomas J. Scriba;Willem A. Hanekom;Willem A. Hanekom;Anne E. Goldfeld

  • The novel tuberculosis vaccine, AERAS-402, induces robust and polyfunctional CD4+ and CD8+ T cells in adults

    Brian Abel;Michele Tameris;Nazma Mansoor;Sebastian Gelderbloem

  • T-cell activation is an immune correlate of risk in BCG vaccinated infants

    Helen A. Fletcher;Helen A. Fletcher;Margaret A. Snowden;Bernard Landry;Wasima Rida

  • COMPASS identifies T-cell subsets correlated with clinical outcomes

    Lin Lin;Greg Finak;Kevin Ushey;Chetan Seshadri

  • Four-Gene Pan-African Blood Signature Predicts Progression to Tuberculosis

    Sara Suliman;Ethan G. Thompson;Jayne Sutherland;January Weiner rd

  • Human MAIT and CD8αα cells develop from a pool of type-17 precommitted CD8 + T cells

    Lucy J. Walker;Yu-Hoi Kang;Matthew O. Smith;Hannah Tharmalingham

  • Bacillus Calmette-Guérin Vaccination of Human Newborns Induces T Cells with Complex Cytokine and Phenotypic Profiles

    Andreia P. Soares;Thomas J. Scriba;Sarah Joseph;Ryhor Harbacheuski

  • Modified vaccinia Ankara-expressing Ag85A, a novel tuberculosis vaccine, is safe in adolescents and children, and induces polyfunctional CD4+ T cells

    Thomas J. Scriba;Michele Tameris;Nazma Mansoor;Erica Smit

  • Influence of BCG vaccine strain on the immune response and protection against tuberculosis

    Nicole Ritz;Nicole Ritz;Willem A. Hanekom;Roy Robins-Browne;Roy Robins-Browne;Warwick J. Britton

  • A multi-cohort study of the immune factors associated with M. tuberculosis infection outcomes

    Roshni Roy Chowdhury;Francesco Vallania;Qianting Yang;Cesar Joel Lopez Angel

  • The Utility of an Interferon Gamma Release Assay for Diagnosis of Latent Tuberculosis Infection and Disease in Children A Systematic Review and Meta-analysis

    Shingai Machingaidze;Charles Shey Wiysonge;Yulieth Gonzalez-Angulo;Mark Hatherill

  • Safety and Immunogenicity of a New Tuberculosis Vaccine, MVA85A, in Healthy Adults in South Africa

    Tony Hawkridge;Thomas J. Scriba;Sebastian Gelderbloem;Erica Smit

Frequent Co-Authors

Thomas J. Scriba
Thomas J. Scriba University of Cape Town
Helen McShane
Helen McShane University of Oxford
Gerhard Walzl
Gerhard Walzl Stellenbosch University
Gilla Kaplan
Gilla Kaplan Bill & Melinda Gates Foundation
Cheryl L. Day
Cheryl L. Day Emory University
Helen A. Fletcher
Helen A. Fletcher London School of Hygiene & Tropical Medicine
Robert J. Wilkinson
Robert J. Wilkinson The Francis Crick Institute
W. Henry Boom
W. Henry Boom Case Western Reserve University
Thomas R. Hawn
Thomas R. Hawn University of Washington
Nigel Curtis
Nigel Curtis Royal Children's Hospital

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