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Immunology

D-Index
77
Citations
20579
World Ranking
1826
National Ranking
162

Research.com Recognitions

  • Fellow of The Academy of Medical Sciences, United Kingdom
  • Fellow of The Academy of Medical Sciences, United Kingdom

Overview

Helen McShane is affiliated with the University of Oxford in the United Kingdom. Their research focuses primarily on the fields of Medicine and Immunology and Microbiology, with significant contributions to Infectious Diseases, Immunology, Epidemiology, Public Health, Environmental and Occupational Health, and Health.

The scientist's key research topics cover areas such as Tuberculosis Research and Epidemiology, Immune responses and vaccinations, Immunodeficiency and Autoimmune Disorders, Mycobacterium research and diagnosis, SARS-CoV-2 and COVID-19 Research, Vaccine Coverage and Hesitancy, and COVID-19 Clinical Research Studies.

They have published extensively, with frequent contributions to journals and venues including:

  • Frontiers in Immunology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • npj Vaccines
  • The Lancet Infectious Diseases
  • Vaccine

Helen McShane's recent papers include:

  • COVID-19 vaccine hesitancy in the UK: the Oxford coronavirus explanations, attitudes, and narratives survey (Oceans) II, 2020, Psychological Medicine
  • Safety, tolerability and viral kinetics during SARS-CoV-2 human challenge in young adults, 2022, Nature Medicine
  • Effects of different types of written vaccination information on COVID-19 vaccine hesitancy in the UK (OCEANS-III): a single-blind, parallel-group, randomised controlled trial, 2021, The Lancet Public Health
  • Injection fears and COVID-19 vaccine hesitancy, 2021, Psychological Medicine
  • Online Social Endorsement and Covid-19 Vaccine Hesitancy in the United Kingdom, 2021, Social Media + Society

The scientist frequently collaborates with other researchers, including Rachel Tanner, Iman Satti, Stephanie A. Harris, Andrew White, and Sally Sharpe.

Helen McShane has been recognized as a Fellow of The Academy of Medical Sciences, United Kingdom.

Best Publications

  • Safety and efficacy of MVA85A, a new tuberculosis vaccine, in infants previously vaccinated with BCG: a randomised, placebo-controlled phase 2b trial

    Michele D Tameris;Mark Hatherill;Bernard S Landry;Thomas J Scriba

  • Recombinant modified vaccinia virus Ankara expressing antigen 85A boosts BCG-primed and naturally acquired antimycobacterial immunity in humans.

    Helen McShane;Ansar A Pathan;Clare R Sander;Sheila M Keating

  • Safety, tolerability and viral kinetics during SARS-CoV-2 human challenge in young adults

    Unknown

  • COVID-19 Vaccine Hesitancy in the UK: The Oxford Coronavirus Explanations, Attitudes, and Narratives Survey (OCEANS) II.

    Daniel Freeman;Daniel Freeman;Bao S. Loe;Andrew Chadwick;Cristian Vaccari

  • Rapid detection of Mycobacterium tuberculosis infection by enumeration of antigen-specific T cells.

    Ajit Lalvani;Ansar A. Pathan;Helen McSHANE;Robert J. Wilkinson

  • Physical, cognitive, and mental health impacts of COVID-19 after hospitalisation (PHOSP-COVID): a UK multicentre, prospective cohort study.

    Rachael A Evans;Hamish McAuley;Ewen M Harrison;Aarti Shikotra

  • Enhanced Immunogenicity and Protective Efficacy Against Mycobacterium tuberculosis of Bacille Calmette-Guérin Vaccine Using Mucosal Administration and Boosting with a Recombinant Modified Vaccinia Virus Ankara

    Nilu P. Goonetilleke;Helen McShane;Carolyn M. Hannan;Richard J. Anderson

  • Direct ex vivo analysis of antigen-specific IFN-gamma-secreting CD4 T cells in Mycobacterium tuberculosis-infected individuals: associations with clinical disease state and effect of treatment.

    Ansar A. Pathan;Katalin A. Wilkinson;Paul Klenerman;Helen McShane

  • Multifunctional, high-level cytokine-producing Th1 cells in the lung, but not spleen, correlate with protection against Mycobacterium tuberculosis aerosol challenge in mice.

    Emily K. Forbes;Clare Sander;Edward O. Ronan;Helen McShane

  • Immunisation with BCG and recombinant MVA85A induces long-lasting, polyfunctional Mycobacterium tuberculosis-specific CD4+ memory T lymphocyte populations.

    Natalie E. R. Beveridge;David A. Price;David A. Price;Joseph P. Casazza;Ansar A. Pathan

  • Enhanced immunogenicity of CD4(+) t-cell responses and protective efficacy of a DNA-modified vaccinia virus Ankara prime-boost vaccination regimen for murine tuberculosis.

    Helen McShane;Helen McShane;Roger Brookes;Sarah C. Gilbert;Adrian V. S. Hill;Adrian V. S. Hill

  • A human immunodeficiency virus 1 (HIV-1) clade A vaccine in clinical trials: stimulation of HIV-specific T-cell responses by DNA and recombinant modified vaccinia virus Ankara (MVA) vaccines in humans.

    Matilu Mwau;Inese Cebere;Julian Sutton;Priscilla Chikoti

  • Viral booster vaccines improve Mycobacterium bovis BCG-induced protection against bovine tuberculosis.

    H. Martin Vordermeier;Bernardo Villarreal-Ramos;Paul J. Cockle;Martin McAulay

  • T-cell activation is an immune correlate of risk in BCG vaccinated infants

    Helen A. Fletcher;Helen A. Fletcher;Margaret A. Snowden;Bernard Landry;Wasima Rida

  • Effects of different types of written vaccination information on COVID-19 vaccine hesitancy in the UK (OCEANS-III): a single-blind, parallel-group, randomised controlled trial.

    Daniel Freeman;Daniel Freeman;Bao Sheng Loe;Ly Mee Yu;Jason Freeman

  • Modified vaccinia Ankara-expressing Ag85A, a novel tuberculosis vaccine, is safe in adolescents and children, and induces polyfunctional CD4+ T cells

    Thomas J. Scriba;Michele Tameris;Nazma Mansoor;Erica Smit

  • MVA.85A boosting of BCG and an attenuated, phoP deficient M. tuberculosis vaccine both show protective efficacy against tuberculosis in rhesus macaques.

    Frank A. W. Verreck;Richard A. W. Vervenne;Ivanela Kondova;Klaas W. van Kralingen

  • Nitric Oxide Modulates Metabolic Remodeling in Inflammatory Macrophages through TCA Cycle Regulation and Itaconate Accumulation

    Jade D. Bailey;Marina Diotallevi;Thomas Nicol;Eileen McNeill

  • Safety and Immunogenicity of a New Tuberculosis Vaccine, MVA85A, in Healthy Adults in South Africa

    Tony Hawkridge;Thomas J. Scriba;Sebastian Gelderbloem;Erica Smit

  • Safety and immunogenicity of a candidate tuberculosis vaccine MVA85A delivered by aerosol in BCG-vaccinated healthy adults: a phase 1, double-blind, randomised controlled trial.

    Iman Satti;Joel Meyer;Stephanie A Harris;Zita-Rose Manjaly Thomas

  • Tuberculosis vaccines: beyond bacille Calmette-Guerin.

    Helen McShane

  • Evaluation of vaccines in the EU TB vaccine cluster using a guinea pig aerosol infection model of tuberculosis

    Ann Williams;Graham J. Hatch;Simon O. Clark;Karen E. Gooch

Frequent Co-Authors

Helen A. Fletcher
Helen A. Fletcher London School of Hygiene & Tropical Medicine
Adrian V. S. Hill
Adrian V. S. Hill University of Oxford
Thomas J. Scriba
Thomas J. Scriba University of Cape Town
Willem A. Hanekom
Willem A. Hanekom University College London
Sarah C. Gilbert
Sarah C. Gilbert University of Oxford
Vivek Naranbhai
Vivek Naranbhai Monash University
Ian D. Poulton
Ian D. Poulton University of Oxford
Hazel M. Dockrell
Hazel M. Dockrell London School of Hygiene & Tropical Medicine
Tom H. M. Ottenhoff
Tom H. M. Ottenhoff Leiden University Medical Center
Michael J. Brennan
Michael J. Brennan Center for Biologics Evaluation and Research

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