World's Best Scientists 2026 revealed!

D-Index & Metrics

Neuroscience

D-Index
34
Citations
10585
World Ranking
9252
National Ranking
3904

Overview

Adrian Handforth is a researcher affiliated with the Louis Stokes Cleveland VA Medical Center in the United States. Their work primarily addresses neurological disorders and treatments, with a strong focus on essential tremor and related neural mechanisms.

Their research spans multiple fields of study including Neuroscience and Medicine, with particular emphasis on Cellular and Molecular Neuroscience and Neurology. They have also contributed to areas such as Molecular Biology, Psychiatry and Mental Health, and Biomedical Engineering.

Major research topics covered by Adrian Handforth include:

  • Neurological disorders and treatments
  • Neuroscience and Neuropharmacology Research
  • Neuroscience and Neural Engineering
  • Ion channel regulation and function
  • Genetic Neurodegenerative Diseases
  • Parkinson's Disease Mechanisms and Treatments
  • Epilepsy research and treatment

Their recent publications illustrate a concentration on essential tremor and its neurobiological underpinnings. Notable papers include:

  • Increased Purkinje Cell Complex Spike and Deep Cerebellar Nucleus Synchrony as a Potential Basis for Syndromic Essential Tremor. A Review and Synthesis of the Literature (2020), published in The Cerebellum
  • A Pilot Double-Blind Randomized Trial of Perampanel for Essential Tremor (2020), published in Movement Disorders Clinical Practice
  • Search for Novel Therapies for Essential Tremor Based on Positive Modulation of α6-Containing GABAA Receptors (2023), published in Tremor and Other Hyperkinetic Movements

Adrian Handforth has collaborated with various coauthors on multiple occasions. Frequent collaborators include Rodger J. Elble, Ram P. Singh, Eric J. Lang, Spyros Papapetropoulos, and Margaret Lee.

Their publications have appeared in several peer-reviewed venues, with multiple works published in Tremor and Other Hyperkinetic Movements, as well as contributions to The Cerebellum, Movement Disorders, Movement Disorders Clinical Practice, and International Review of Neurobiology.

Best Publications

  • Electrical stimulation of the anterior nucleus of thalamus for treatment of refractory epilepsy

    Robert Fisher;Vicenta Salanova;Thomas Witt;Robert Worth

  • A Comparison of Four Treatments for Generalized Convulsive Status Epilepticus

    D M Treiman;P D Meyers;N Y Walton;N Y Walton;J F Collins

  • Vagus nerve stimulation therapy for partial-onset seizures A randomized active-control trial

    Adrian Handforth;Adrian Handforth;C. M. DeGiorgio;S. C. Schachter;B. M. Uthman

  • Long-term efficacy and safety of thalamic stimulation for drug-resistant partial epilepsy

    Vicenta Salanova;Thomas Witt;Robert Worth;Thomas R. Henry

  • Prospective Long-Term Study of Vagus Nerve Stimulation for the Treatment of Refractory Seizures

    C. M. DeGiorgio;S. C. Schachter;A. Handforth;M. Salinsky

  • Mice devoid of γ-aminobutyrate type A receptor β3 subunit have epilepsy, cleft palate, and hypersensitive behavior

    Gregg E. Homanics;Timothy M. DeLorey;Leonard L. Firestone;Joseph J. Quinlan

  • Mice lacking the beta3 subunit of the GABAA receptor have the epilepsy phenotype and many of the behavioral characteristics of Angelman syndrome.

    T. M. DeLorey;A. Handforth;S. G. Anagnostaras;G. E. Homanics

  • Reassessment: Vagus nerve stimulation for epilepsy: A Report of the Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology

    Robert S. Fisher;Adrian Handforth

  • Destruction of peripheral C-fibers does not alter subsequent vagus nerve stimulation-induced seizure suppression in rats.

    Scott E. Krahl;Shayani S. Senanayake;Adrian Handforth

  • Markedly Increased Mesiotemporal Lobe Metabolism in a Case with PLEDs: Further Evidence that PLEDs are a Manifestation of Partial Status Epilepticus

    Adrian Handforth;Jung Tung Cheng;Mark A. Mandelkern;David M. Treiman

  • Deep brain stimulation of the subthalamic nucleus as adjunct treatment for refractory epilepsy.

    Adrian Handforth;Antonio A. F. DeSalles;Scott E. Krahl

  • Vagus nerve stimulation: analysis of device parameters in 154 patients during the long-term XE5 study.

    Christopher M. DeGiorgio;Jaye Thompson;Paul Lewis;Stacey Arrambide

  • Harmaline-induced tremor as a potential preclinical screening method for essential tremor medications

    Fredricka C. Martin;Anh Thu Le;Adrian Handforth

  • Functional [14C]2-deoxyglucose mapping of progressive states of status epilepticus induced by amygdala stimulation in rat.

    Adrian Handforth;Robert F. Ackermann

  • Harmaline Tremor: Underlying Mechanisms in a Potential Animal Model of Essential Tremor

    Adrian Handforth

  • T-type calcium channel antagonists suppress tremor in two mouse models of essential tremor.

    Adrian Handforth;Gregg E. Homanics;Douglas F. Covey;Kathiresan Krishnan

  • Mapping of limbic seizure progressions utilizing the electrogenic status epilepticus model and the 14C-2-deoxyglucose method.

    Adrian Handforth;Robert F. Ackermann

  • Carbenoxolone and mefloquine suppress tremor in the harmaline mouse model of essential tremor.

    Fredricka C. Martin;Adrian Handforth

  • Vagus nerve stimulation therapy for partial-onset seizures

    Adrian Handforth;C. M. DeGiorgio;S. C. Schachter;B. M. Uthman

  • Functional mapping of the early stages of status epilepticus: A 14C-2-deoxyglucose study in the lithium-pilocarpine model in rat

    Unknown

  • GABAA receptor β3 subunit gene-deficient heterozygous mice show parent-of-origin and gender-related differences in β3 subunit levels, EEG, and behavior

    Patricia Liljelund;Adrian Handforth;Gregg E. Homanics;Richard W. Olsen

  • Clinical Research Prospective Long-Term Study of Vagus Nerve Stimulation for the Treatment of Refractory Seizures

    C. M. DeGiorgio;S. C. Schachter;A. Handforth;M. Salinsky

Frequent Co-Authors

Gregg E. Homanics
Gregg E. Homanics University of Pittsburgh
Thomas R. Henry
Thomas R. Henry University of Minnesota
Basim M. Uthman
Basim M. Uthman Weill Cornell Medical College in Qatar
David M. Treiman
David M. Treiman Barrow Neurological Institute
Ivan Osorio
Ivan Osorio University of Kansas
Martin C. Salinsky
Martin C. Salinsky Oregon Health & Science University
Steven C. Schachter
Steven C. Schachter Beth Israel Deaconess Medical Center
Richard W. Olsen
Richard W. Olsen University of California, Los Angeles
Douglas Labar
Douglas Labar Cornell University
Rodger J. Elble
Rodger J. Elble Southern Illinois University School of Medicine

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

If you're interested in studying neuroscience in the USA, you may also want to explore related online degrees that offer flexibility and solid career prospects. Some of the most profitable degrees in the science and healthcare sectors can provide excellent long-term earning potential. Many of these programs equip you with versatile skills in data analysis, psychology, and biology.

For those seeking a more affordable path, there are cheap online colleges that accept fafsa. These options help reduce financial barriers while giving you access to bachelor's or associate programs in neuroscience-related fields.

Alternatively, pursuing online certificate programs that pay well can be a smart move. Certificates in biotechnology, clinical research, or data science provide specialized skills in less time than a full degree.

If you’re looking for flexibility and a manageable workload, consider choosing from a selection of online college courses. These can be a good first step toward a rewarding neuroscience career or an opportunity to upskill while balancing other commitments.

Best Scientists Citing Adrian Handforth

Trending Scientists