World's Best Scientists 2026 revealed!

D-Index & Metrics

Neuroscience

D-Index
73
Citations
16277
World Ranking
2233
National Ranking
1061

Biology and Biochemistry

D-Index
73
Citations
16240
World Ranking
6037
National Ranking
2845

Overview

Gregg E. Homanics is affiliated with the University of Pittsburgh in the United States and has a research focus spanning several interconnected areas within biochemistry, genetics, molecular biology, neuroscience, and medicine. Their work is distributed across multiple disciplines including molecular biology, cellular and molecular neuroscience, physiology, pediatrics, perinatology, child health, and genetics.

The scientist's research topics cover a broad range of subjects, notably:

  • Neuroscience and neuropharmacology research
  • Alzheimer's disease research and treatments
  • Neurotransmitter receptor influence on behavior
  • Receptor mechanisms and signaling
  • Genetics, aging, and longevity in model organisms
  • Prenatal substance exposure effects
  • Memory and neural mechanisms

Recent significant papers authored or co-authored by Homanics include:

  • "Effect of chronic intermittent ethanol vapor exposure on RNA content of brain-derived extracellular vesicles" (2022), published in Alcohol
  • "MAP2 is differentially phosphorylated in schizophrenia, altering its function" (2021), published in Molecular Psychiatry
  • "Bridging the rodent to human translational gap: Marmosets as model systems for the study of Alzheimer's disease" (2023), published in Alzheimer's & Dementia Translational Research & Clinical Interventions
  • "G protein-biased GPR3 signaling ameliorates amyloid pathology in a preclinical Alzheimer's disease mouse model" (2022), published in Proceedings of the National Academy of Sciences
  • "Gabra2 is a genetic modifier of Dravet syndrome in mice" (2021), published in Mammalian Genome

Homanics frequently collaborates with several researchers, including:

  • Stacey J. Sukoff Rizzo
  • Jung Eun Park
  • Afonso C. Silva
  • Peter L. Strick
  • Gregory W. Carter

The most frequent venues where Homanics publishes include:

  • Alzheimer's & Dementia
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Alcohol
  • Molecular Psychiatry
  • Genes Brain & Behavior

The work of Gregg E. Homanics is situated at the intersection of molecular biology and neuroscience with a strong emphasis on biochemistry, genetics, and disease models relevant to human health such as Alzheimer's disease and neuropsychiatric conditions. Their collaboration network and publication record demonstrate a consistent engagement with multidisciplinary teams and a variety of specialized scientific journals.

Best Publications

  • Attenuated sensitivity to neuroactive steroids in γ-aminobutyrate type A receptor delta subunit knockout mice

    Robert M. Mihalek;Pradeep K. Banerjee;Esa R. Korpi;Joseph J. Quinlan

  • Mice devoid of γ-aminobutyrate type A receptor β3 subunit have epilepsy, cleft palate, and hypersensitive behavior

    Gregg E. Homanics;Timothy M. DeLorey;Leonard L. Firestone;Joseph J. Quinlan

  • Mice lacking the beta3 subunit of the GABAA receptor have the epilepsy phenotype and many of the behavioral characteristics of Angelman syndrome.

    T. M. DeLorey;A. Handforth;S. G. Anagnostaras;G. E. Homanics

  • Reciprocal Inhibitory Connections and Network Synchrony in the Mammalian Thalamus

    Molly M. Huntsman;Darrell M. Porcello;Gregg E. Homanics;Timothy M. DeLorey

  • Inhaled anesthetics and immobility: Mechanisms, mysteries, and minimum alveolar anesthetic concentration

    James M. Sonner;Joseph F. Antognini;Robert C. Dutton;Pamela Flood

  • GABAA receptor α4 subunits mediate extrasynaptic inhibition in thalamus and dentate gyrus and the action of gaboxadol

    D. Chandra;F. Jia;J. Liang;Z. Peng

  • GABAA receptor α1 subunit deletion prevents developmental changes of inhibitory synaptic currents in cerebellar neurons

    Stefano Vicini;Carolyn Ferguson;Kate Prybylowski;Jason Kralic

  • A new naturally occurring GABA A receptor subunit partnership with high sensitivity to ethanol

    Joseph Glykys;Zechun Peng;Dev Chandra;Gregg E Homanics

  • Brains, Genes, and Primates

    Juan Carlos Izpisua Belmonte;Edward M. Callaway;Sarah J. Caddick;Patricia Churchland

  • Gabrb3 gene deficient mice exhibit impaired social and exploratory behaviors, deficits in non-selective attention and hypoplasia of cerebellar vermal lobules: A potential model of autism spectrum disorder

    Timothy M. DeLorey;Peyman Sahbaie;Ezzat Hashemi;Gregg E. Homanics

  • GABAA receptor changes in δ subunit‐deficient mice: Altered expression of α4 and γ2 subunits in the forebrain

    Zechun Peng;Birgit Hauer;Robert M. Mihalek;Gregg E. Homanics

  • Pathophysiological and neurochemical mechanisms of postoperative nausea and vomiting.

    Charles C. Horn;William J. Wallisch;Gregg E. Homanics;John P. Williams

  • Adenosine A1 receptor knockout mice develop lethal status epilepticus after experimental traumatic brain injury.

    Patrick M Kochanek;Vincent A Vagni;Keri L Janesko;Christopher B Washington

  • Disruption of GABAA Receptors on GABAergic Interneurons Leads to Increased Oscillatory Power in the Olfactory Bulb Network

    Zoltan Nusser;Leslie M. Kay;Leslie M. Kay;Gilles Laurent;Gregg E. Homanics

  • Genetic essential tremor in γ-aminobutyric acidA receptor α1 subunit knockout mice

    Jason E. Kralic;Jason E. Kralic;Hugh E. Criswell;Jessica L. Osterman;Todd K. O’Buckley

  • Molecular and Pharmacological Characterization of GABAA Receptor α1 Subunit Knockout Mice

    J. E. Kralic;E. R. Korpi;T. K. O'Buckley;G. E. Homanics

  • Gene knockout of the alpha6 subunit of the gamma-aminobutyric acid type A receptor: lack of effect on responses to ethanol, pentobarbital, and general anesthetics.

    Gregg E. Homanics;Carolyn Ferguson;Joseph J. Quinlan;Jodi Daggett

  • Mild dyslipidemia in mice following targeted inactivation of the hepatic lipase gene.

    G. E. Homanics;H. V. De Silva;J. Osada;S. H. Zhang

  • Taurine Is a Potent Activator of Extrasynaptic GABAA Receptors in the Thalamus

    Fan Jia;Minerva Yue;Dev Chandra;Angelo Keramidas

  • Pharmacologic and behavioral responses of inbred C57BL/6J and strain 129/SvJ mouse lines.

    Gregg E Homanics;Joseph J Quinlan;Leonard L Firestone

  • The α1 Subunit of the GABA(A) Receptor Modulates Fear Learning and Plasticity in the Lateral Amygdala

    Brian J Wiltgen;Brian J Wiltgen;Bill P Godsil;Zechun Peng;Faysal Saab

Frequent Co-Authors

Neil L. Harrison
Neil L. Harrison Columbia University
Yuri A. Blednov
Yuri A. Blednov The University of Texas at Austin
Richard W. Olsen
Richard W. Olsen University of California, Los Angeles
R. Adron Harris
R. Adron Harris The University of Texas at Austin
Michael S. Fanselow
Michael S. Fanselow University of California, Los Angeles
Esa R. Korpi
Esa R. Korpi University of Helsinki
Werner Sieghart
Werner Sieghart Medical University of Vienna
David M. Lovinger
David M. Lovinger National Institutes of Health
Carolyn R. Houser
Carolyn R. Houser University of California, Los Angeles
A. Leslie Morrow
A. Leslie Morrow University of North Carolina at Chapel Hill

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