World's Best Scientists 2026 revealed!
Jean-Marc Fritschy

Jean-Marc Fritschy

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Neuroscience
Switzerland
2026

D-Index & Metrics

Neuroscience

D-Index
116
Citations
42893
World Ranking
443
National Ranking
7

Research.com Recognitions

  • 2026 - Research.com Neuroscience in Switzerland Leader Award
  • 2025 - Research.com Neuroscience in Switzerland Leader Award
  • 2022 - Research.com Neuroscience in Switzerland Leader Award

Overview

Jean-Marc Fritschy is affiliated with the University of Zurich in Switzerland. Their research primarily focuses on neuroscience, with interdisciplinary work extending into biochemistry, genetics, and molecular biology. Specific subfields of study include cellular and molecular neuroscience, developmental neuroscience, molecular biology, neurology, and cancer research.

Their scientific contributions cover several main topics, notably:

  • Neurogenesis and neuroplasticity mechanisms
  • Neuroscience and neuropharmacology research
  • Neuroinflammation and neurodegeneration mechanisms
  • MicroRNA in disease regulation
  • Receptor mechanisms and signaling
  • Neurotransmitter receptor influence on behavior
  • Erythropoietin and anemia treatment

Frequent coauthors in Fritschy's work include Mostafa A. Aboouf, Max Gassmann, Edith M. Schneider Gasser, Christina Koester-Hegmann, and Lena Rubi.

The scientist has published in various venues, with multiple papers appearing in:

  • Scientific Reports
  • eNeuro
  • Journal of Neurophysiology
  • European Journal of Neuroscience
  • Research Square

Recent publications highlight a focus on GABAergic transmission and developmental neurobiology. Notable papers include:

  • "Erythropoietin Stimulates GABAergic Maturation in the Mouse Hippocampus" (2021, eNeuro)
  • "Aberrant expression of PAR bZIP transcription factors is associated with epileptogenesis, focus on hepatic leukemia factor" (2020, Scientific Reports)
  • "Increased GABAergic transmission in neuropeptide Y-expressing neurons in the dopamine-depleted murine striatum" (2020, Journal of Neurophysiology)
  • "Dopamine depletion induces neuron-specific alterations of GABAergic transmission in the mouse striatum" (2020, European Journal of Neuroscience)
  • "Erythropoietin regulates developmental myelination in the brain stimulating postnatal oligodendrocyte maturation" (2023, Scientific Reports)

Best Publications

  • Benzodiazepine actions mediated by specific γ-aminobutyric acid A receptor subtypes

    Uwe Rudolph;Florence Crestani;Dietmar Benke;Ina Brünig

  • GABAA-receptor heterogeneity in the adult rat brain: differential regional and cellular distribution of seven major subunits.

    Jean-Marc Fritschy;Hanns Mohler

  • Molecular and neuronal substrate for the selective attenuation of anxiety.

    Karin Löw;Florence Crestani;Ruth Keist;Dietmar Benke

  • Postsynaptic clustering of major GABAA receptor subtypes requires the gamma 2 subunit and gephyrin.

    Christian Essrich;Matthias Lorez;Jack A. Benson;Jean Marc Fritschy

  • A New Benzodiazepine Pharmacology

    H. Möhler;J. M. Fritschy;Uwe Rudolph

  • Decreased GABA A -receptor clustering results in enhanced anxiety and a bias for threat cues

    Florence Crestani;Matthias Lorez;Kristin Baer;Christian Essrich

  • Trace fear conditioning involves hippocampal α5 GABAA receptors

    F. Crestani;R. Keist;J.-M. Fritschy;D. Benke

  • Specific GABAA Circuits for Visual Cortical Plasticity

    Michela Fagiolini;Joan Marc Fritschy;Karin Löw;Hanns Möhler;Hanns Möhler

  • Switch in the expression of rat GABAA-receptor subtypes during postnatal development: an immunohistochemical study

    JM Fritschy;J Paysan;A Enna;H Mohler

  • Benzodiazepine-insensitive mice generated by targeted disruption of the gamma 2 subunit gene of gamma-aminobutyric acid type A receptors

    Uwe Gunther;Jack Benson;Dietmar Benke;Jean-Marc Fritschy

  • NMDA receptor heterogeneity during postnatal development of the rat brain: differential expression of the NR2A, NR2B, and NR2C subunit proteins.

    Andreas Wenzel;Jean Marc Fritschy;Hanns Mohler;Dietmar Benke

  • Reversal of pathological pain through specific spinal GABAA receptor subtypes.

    Julia Knabl;Robert Witschi;Katharina Hösl;Heiko Reinold

  • Differential synaptic localization of two major gamma-aminobutyric acid type A receptor alpha subunits on hippocampal pyramidal cells.

    Zoltan Nusser;Werner Sieghart;Dietmar Benke;Jean Marc Fritschy

  • Evolution of hippocampal epileptic activity during the development of hippocampal sclerosis in a mouse model of temporal lobe epilepsy.

    V. Riban;V. Bouilleret;B.T. Pham-Lê;J.-M. Fritschy

  • Neural bases for addictive properties of benzodiazepines

    Kelly R. Tan;Matthew Brown;Gwenaël Labouébe;Cédric Yvon

  • Gephyrin: a master regulator of neuronal function?

    Shiva K. Tyagarajan;Jean-Marc Fritschy

  • Localization of the organic anion transporting polypeptide 2 (Oatp2) in capillary endothelium and choroid plexus epithelium of rat brain

    Bo Gao;Bruno Stieger;Birgitta Noé;Jean-Marc Fritschy

  • Formation and plasticity of GABAergic synapses: physiological mechanisms and pathophysiological implications

    Jean-Marc Fritschy;Ina Brünig

  • Five subtypes of type A gamma-aminobutyric acid receptors identified in neurons by double and triple immunofluorescence staining with subunit-specific antibodies.

    J M Fritschy;D Benke;S Mertens;W H Oertel

  • Intact sorting, targeting, and clustering of γ-aminobutyric acid A receptor subtypes in hippocampal neurons in vitro

    Ina Brünig;Eleonora Scotti;Corinne Sidler;Jean-Marc Fritschy

Frequent Co-Authors

Hanns Ulrich Zeilhofer
Hanns Ulrich Zeilhofer University of Zurich
Marco Sassoè-Pognetto
Marco Sassoè-Pognetto University of Turin
Martin Sarter
Martin Sarter University of Michigan–Ann Arbor
Kaspar E. Vogt
Kaspar E. Vogt University of Tsukuba
Wolfgang Härtig
Wolfgang Härtig Leipzig University
Otto W. Witte
Otto W. Witte Friedrich Schiller University Jena
Heinz Gregor Wieser
Heinz Gregor Wieser University of Zurich
Stephen J. Moss
Stephen J. Moss Tufts University
A. Leslie Morrow
A. Leslie Morrow University of North Carolina at Chapel Hill
Gregg E. Homanics
Gregg E. Homanics University of Pittsburgh

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