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Biology and Biochemistry

D-Index
59
Citations
15845
World Ranking
12366
National Ranking
221

Overview

Dietmar Benke is a researcher affiliated with the University of Zurich in Switzerland. Their work primarily spans the fields of Neuroscience, Biochemistry, Genetics and Molecular Biology, and Medicine, with a focus on specialized subfields such as Cellular and Molecular Neuroscience, Molecular Biology, Surgery, Neurology, and Physiology.

The main topics of their research include Neuroscience and Neuropharmacology Research, Receptor Mechanisms and Signaling, Neuropeptides and Animal Physiology, Pancreatic function and diabetes, Neuroinflammation and Neurodegeneration Mechanisms, Photoreceptor and optogenetics research, and Neurotransmitter Receptor Influence on Behavior.

Among frequent collaborators, Dietmar Benke has coauthored extensively with Musadiq A. Bhat, Tommaso Patriarchi, Mohammad Hleihil, Thomas Grampp, and Elyse T. Williams.

The publication venues where Dietmar Benke's work commonly appears include:

  • Zenodo (CERN European Organization for Nuclear Research)
  • eLife
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Frontiers in Molecular Neuroscience
  • Cell Reports

Representative publications spanning recent years include:

  • Sensitive multicolor indicators for monitoring norepinephrine in vivo, 2023, Nature Methods
  • Astrocyte dysfunction increases cortical dendritic excitability and promotes cranial pain in familial migraine, 2020, Science Advances
  • Calreticulin mutations affect its chaperone function and perturb the glycoproteome, 2022, Cell Reports
  • Bidirectional regulation of distinct memory domains by α5-subunit-containing GABAA receptors in CA1 pyramidal neurons, 2020, Learning & Memory
  • GABAB Receptors and Pain, 2020, Current topics in behavioral neurosciences

Best Publications

  • Benzodiazepine actions mediated by specific γ-aminobutyric acid A receptor subtypes

    Uwe Rudolph;Florence Crestani;Dietmar Benke;Ina Brünig

  • Molecular and neuronal substrate for the selective attenuation of anxiety.

    Karin Löw;Florence Crestani;Ruth Keist;Dietmar Benke

  • Decreased GABA A -receptor clustering results in enhanced anxiety and a bias for threat cues

    Florence Crestani;Matthias Lorez;Kristin Baer;Christian Essrich

  • Trace fear conditioning involves hippocampal α5 GABAA receptors

    F. Crestani;R. Keist;J.-M. Fritschy;D. Benke

  • Benzodiazepine-insensitive mice generated by targeted disruption of the gamma 2 subunit gene of gamma-aminobutyric acid type A receptors

    Uwe Gunther;Jack Benson;Dietmar Benke;Jean-Marc Fritschy

  • NMDA receptor heterogeneity during postnatal development of the rat brain: differential expression of the NR2A, NR2B, and NR2C subunit proteins.

    Andreas Wenzel;Jean Marc Fritschy;Hanns Mohler;Dietmar Benke

  • Organic Anion-Transporting Polypeptides Mediate Transport of Opioid Peptides across Blood-Brain Barrier

    Bo Gao;Bruno Hagenbuch;Gerd A. Kullak-Ublick;Dietmar Benke

  • Differential synaptic localization of two major gamma-aminobutyric acid type A receptor alpha subunits on hippocampal pyramidal cells.

    Zoltan Nusser;Werner Sieghart;Dietmar Benke;Jean Marc Fritschy

  • Synapse‐specific localization of NMDA and GABAA receptor subunits revealed by antigen‐retrieval immunohistochemistry

    Jean‐Marc Fritschy;Oliver Weinmann;Andreas Wenzel;Dietmar Benke

  • Adjacent phosphorylation sites on GABAA receptor beta subunits determine regulation by cAMP-dependent protein kinase.

    Bernard J. McDonald;Alessandra Amato;Christopher N. Connolly;Dietmar Benke

  • Neuron-specific expression of GABAA-receptor subtypes: Differential association of theα1- andα3-subunits with serotonergic and gabaergic neurons

    B. Gao;J.M. Fritschy;D. Benke;H. Mohler

  • GABAA receptors display association of gamma 2-subunit with alpha 1- and beta 2/3-subunits.

    D Benke;S Mertens;A Trzeciak;D Gillessen

  • Distribution, prevalence, and drug binding profile of gamma-aminobutyric acid type A receptor subtypes differing in the beta-subunit variant.

    D Benke;J M Fritschy;A Trzeciak;W Bannwarth

  • Genetic inactivation of the Serotonin(1A) receptor in mice results in downregulation of major GABA(A) receptor alpha subunits, reduction of GABA(A) receptor binding, and benzodiazepine-resistant anxiety.

    Etienne Sibille;Constantine Pavlides;Dietmar Benke;Miklos Toth

  • GABA A receptors as in vivo substrate for the anxiolytic action of valerenic acid, a major constituent of valerian root extracts.

    Dietmar Benke;Andrea Barberis;Sascha Kopp;Karl Heinz Altmann

  • The gamma 2 subunit of the GABAA receptor is concentrated in synaptic junctions containing the alpha 1 and beta 2/3 subunits in hippocampus, cerebellum and globus pallidus.

    P Somogyi;J.-M Fritschy;D Benke;J.D.B Roberts

  • GABAA receptor populations with novel subunit combinations and drug binding profiles identified in brain by alpha 5- and delta-subunit-specific immunopurification.

    S Mertens;D Benke;H Mohler

  • Distribution of NMDA receptor subunit proteins NR2A, 2B, 2C and 2D in rat brain.

    Andreas Wenzel;Louis Scheurer;Ralf Künzi;Jean Marc Fritschy

  • A schizophrenia-related sensorimotor deficit links α3-containing GABAA receptors to a dopamine hyperfunction

    B. K. Yee;R. Keist;L. Von Boehmer;R. Studer

  • Developmental and regional expression of NMDA receptor subtypes containing the NR2D subunit in rat brain.

    A. Wenzel;M. Villa;H. Mohler;D. Benke

Frequent Co-Authors

Hanns Möhler
Hanns Möhler University of Zurich
Jean-Marc Fritschy
Jean-Marc Fritschy University of Zurich
Hanns Ulrich Zeilhofer
Hanns Ulrich Zeilhofer University of Zurich
H. Möhler
H. Möhler University of Zurich
Andreas Wenzel
Andreas Wenzel Novartis (Switzerland)
Horst Bluethmann
Horst Bluethmann Roche (Switzerland)
Adriano Aguzzi
Adriano Aguzzi University of Zurich
Bernhard Lüscher
Bernhard Lüscher RWTH Aachen University
Benjamin K. Yee
Benjamin K. Yee Hong Kong Polytechnic University
Joram Feldon
Joram Feldon ETH Zurich

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