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Ruth M. McKernan

D-Index & Metrics

Neuroscience

D-Index
56
Citations
14070
World Ranking
4473
National Ranking
2027

Research.com Recognitions

  • Fellow of The Academy of Medical Sciences, United Kingdom

Best Publications

  • Which GABAA-receptor subtypes really occur in the brain?

    Ruth M. McKernan;Paul J. Whiting

  • Sedative but not anxiolytic properties of benzodiazepines are mediated by the GABA(A) receptor alpha1 subtype.

    R M McKernan;T W Rosahl;D S Reynolds;C Sur

  • Enhanced Learning and Memory and Altered GABAergic Synaptic Transmission in Mice Lacking the α5 Subunit of the GABAAReceptor

    Neil Collinson;Frederick M. Kuenzi;Wolfgang Jarolimek;Karen A. Maubach

  • NMDA receptor pathways as drug targets

    John A. Kemp;Ruth M. McKernan

  • Another mechanism for creating diversity in gamma-aminobutyrate type A receptors: RNA splicing directs expression of two forms of gamma 2 phosphorylation site

    Paul Whiting;Ruth M. McKernan;Leslie L. Iversen

  • theta, a novel gamma-aminobutyric acid type A receptor subunit.

    T. P. Bonnert;R. M. Mckernan;S. Farrar;B. Le Bourdelles

  • Ligand-Gated Ion Channel Subunit Partnerships: GABAAReceptor α6 Subunit Gene Inactivation Inhibits δ Subunit Expression

    A. Jones;E. R. Korpi;R. M. McKernan;R. Pelz

  • Sedation and Anesthesia Mediated by Distinct GABAA Receptor Isoforms

    David S. Reynolds;Thomas W. Rosahl;Jennifer Cirone;Gillian F. O'Meara

  • Stoichiometry of a Ligand-gated Ion Channel Determined by Fluorescence Energy Transfer

    Sophie J. Farrar;Paul J. Whiting;Timothy P. Bonnert;Ruth M. McKernan

  • Preferential coassembly of alpha4 and delta subunits of the gamma-aminobutyric acidA receptor in rat thalamus.

    Cyrille Sur;Sophie J. Farrar;Julie Kerby;Paul J. Whiting

  • Evidence for a Significant Role of α3-Containing GABAA Receptors in Mediating the Anxiolytic Effects of Benzodiazepines

    Rebecca Dias;Wayne F. A. Sheppard;Rosa L. Fradley;Elizabeth M. Garrett

  • Structure and Pharmacology of Vertebrate GABAA Receptor Subtypes

    Paul J. Whiting;Ruth M. McKernan;Keith A. Wafford

  • GABAA receptor subtypes immunopurified from rat brain with α subunit-specific antibodies have unique pharmacological properties

    Ruth M. McKernan;Kathleen Quirk;Richard Prince;Paul A. Cox

  • Loss of the major GABA(A) receptor subtype in the brain is not lethal in mice.

    Cyrille Sur;Keith A. Wafford;David S. Reynolds;Karen L. Hadingham

  • TPA023 [7-(1,1-dimethylethyl)-6-(2-ethyl-2H-1,2,4-triazol-3-ylmethoxy)-3-(2-fluorophenyl)-1,2,4-triazolo[4,3-b]pyridazine], an agonist selective for alpha2- and alpha3-containing GABAA receptors, is a nonsedating anxiolytic in rodents and primates.

    John R. Atack;Keith A. Wafford;Spencer J. Tye;Susan M. Cook

  • α4β3δ GABAAReceptors Characterized by Fluorescence Resonance Energy Transfer-derived Measurements of Membrane Potential

    Charles E. Adkins;Gopalan V. Pillai;Julie Kerby;Timothy P. Bonnert

  • L-655,708 enhances cognition in rats but is not proconvulsant at a dose selective for α5-containing GABAA receptors

    John R. Atack;Peter J. Bayley;Guy R. Seabrook;Keith A. Wafford

  • DIFFERENCES IN AGONIST/ANTAGONIST BINDING AFFINITY AND RECEPTOR TRANSDUCTION USING RECOMBINANT HUMAN GAMMA -AMINOBUTYRIC ACID TYPE A RECEPTORS

    Bjarke Ebert;Sally A. Thompson;Koralia Saounatsou;Ruth McKernan

  • [ 3 H]L-655,708, a Novel Ligand Selective for the Benzodiazepine Site of GABA A Receptors which Contain the α5 Subunit

    K. Quirk;P. Blurton;S. Fletcher;P. Leeson

  • Effect of alpha subunit on allosteric modulation of ion channel function in stably expressed human recombinant gamma-aminobutyric acid(A) receptors determined using (36)Cl ion flux.

    Alison J. Smith;Luanda Alder;Jonathan Silk;Charles Adkins

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