World's Best Scientists 2026 revealed!

D-Index & Metrics

Chemistry

D-Index
68
Citations
13977
World Ranking
6670
National Ranking
2007

Biology and Biochemistry

D-Index
69
Citations
14233
World Ranking
7538
National Ranking
3425

Research.com Recognitions

  • 2014 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Lai-Xi Wang is affiliated with the University of Maryland, College Park in the United States. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, with significant contributions also in Medicine. Key subfields of their work include Molecular Biology, Radiology, Nuclear Medicine and Imaging, Immunology, Organic Chemistry, and Infectious Diseases.

The research topics Lai-Xi Wang engages with cover a diverse range of areas, particularly focusing on Glycosylation and Glycoproteins Research, Monoclonal and Polyclonal Antibodies Research, Carbohydrate Chemistry and Synthesis, Galectins and Cancer Biology, as well as SARS-CoV-2 and COVID-19 Research and related Clinical Studies.

Their most frequent co-authors include:

  • Guanghui Zong
  • Chao Li
  • Qiang Yang
  • Chong Ou
  • Sunaina Kiran Prabhu

Publication venues where Lai-Xi Wang has regularly contributed include:

  • Nature Communications
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Bioconjugate Chemistry
  • Proceedings of the National Academy of Sciences
  • ACS Chemical Biology

Representative recent papers authored by Lai-Xi Wang include the following:

  • "FcRn, but not FcγRs, drives maternal-fetal transplacental transport of human IgG antibodies" (2020, Proceedings of the National Academy of Sciences)
  • "CTLA-4 expression by B-1a B cells is essential for immune tolerance" (2021, Nature Communications)
  • "Protection against SARS-CoV-2 infection by a mucosal vaccine in rhesus macaques" (2021, JCI Insight)
  • "Structure and dynamics of an α-fucosidase reveal a mechanism for highly efficient IgG transfucosylation" (2020, Nature Communications)
  • "Sequential Glycosylation of Proteins with Substrate-Specific N-Glycosyltransferases" (2020, ACS Central Science)

Lai-Xi Wang was recognized as a Fellow of the American Association for the Advancement of Science (AAAS) in 2014.

Best Publications

  • Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9

    Jason S. McLellan;Marie Pancera;Chris Carrico;Jason Gorman

  • Chemoenzymatic glycoengineering of intact IgG antibodies for gain of functions

    Wei Huang;John Giddens;Shu Quan Fan;Christian Toonstra

  • Structural basis for diverse N-glycan recognition by HIV-1–neutralizing V1–V2–directed antibody PG16

    Marie Pancera;Syed Shahzad-Ul-Hussan;Nicole A. Doria-Rose;Jason S. McLellan

  • Modulating IgG effector function by Fc glycan engineering.

    Tiezheng Li;David J. DiLillo;Stylianos Bournazos;John P. Giddens

  • Sialylation of IgG Fc domain impairs complement-dependent cytotoxicity

    Isaak Quast;Christian W. Keller;Michael A. Maurer;John P. Giddens

  • Mutants of Mucor hiemalis Endo-β-N-acetylglucosaminidase Show Enhanced Transglycosylation and Glycosynthase-like Activities

    Midori Umekawa;Wei Huang;Bing Li;Kiyotaka Fujita

  • Chemoenzymatic Methods for the Synthesis of Glycoproteins

    Chao Li;Lai-Xi Wang

  • Chemoenzymatic Synthesis and Fcγ Receptor Binding of Homogeneous Glycoforms of Antibody Fc Domain. Presence of a Bisecting Sugar Moiety Enhances the Affinity of Fc to FcγIIIa Receptor

    Guozhang Zou;Hirofumi Ochiai;Wei Huang;Qiang Yang

  • Enzymatic transglycosylation for glycoconjugate synthesis.

    Lai-Xi Wang;Wei Huang

  • A combined method for producing homogeneous glycoproteins with eukaryotic N-glycosylation

    Flavio Schwarz;Wei Huang;Cishan Li;Benjamin L Schulz

  • Highly efficient endoglycosidase-catalyzed synthesis of glycopeptides using oligosaccharide oxazolines as donor substrates.

    Bing Li;Ying Zeng;Steven Hauser;Haijing Song

  • Glycosynthases Enable a Highly Efficient Chemoenzymatic Synthesis of N-Glycoproteins Carrying Intact Natural N-Glycans

    Wei Huang;Cishan Li;Bing Li;Midori Umekawa

  • Structural characterization of the symbiotically important low-molecular-weight succinoglycan of Sinorhizobium meliloti.

    Lai-Xi Wang;Ying Wang;Brett Pellock;Graham C. Walker

  • Chemical and chemoenzymatic synthesis of glycoproteins for deciphering functions.

    Lai-Xi Wang;Mohammed N. Amin

  • Emerging technologies for making glycan-defined glycoproteins.

    Lai-Xi Wang;Joseph V. Lomino

  • Binding of high-mannose-type oligosaccharides and synthetic oligomannose clusters to human antibody 2G12: implications for HIV-1 vaccine design.

    Lai-Xi Wang;Jiahong Ni;Suddham Singh;Hengguang Li

  • Toward a carbohydrate-based HIV-1 vaccine: synthesis and immunological studies of oligomannose-containing glycoconjugates.

    Jiahong Ni;Haijing Song;Yadong Wang;Nicholas M. Stamatos

  • Coexistence of potent HIV-1 broadly neutralizing antibodies and antibody-sensitive viruses in a viremic controller

    Natalia T. Freund;Haoqing Wang;Louise Scharf;Lilian Nogueira

  • Resveratrol glucuronides as the metabolites of resveratrol in humans: characterization, synthesis, and anti-HIV activity.

    Lai-Xi Wang;Alonso Heredia;Haijing Song;Zhaojun Zhang

  • Efficient Glycosynthase Mutant Derived from Mucor hiemalis Endo-β-N-acetylglucosaminidase Capable of Transferring Oligosaccharide from Both Sugar Oxazoline and Natural N-Glycan

    Midori Umekawa;Cishan Li;Takayuki Higashiyama;Wei Huang

  • Chemoenzymatic synthesis of glycopeptides and glycoproteins through endoglycosidase-catalyzed transglycosylation

    Lai-Xi Wang

Frequent Co-Authors

Yuan C. Lee
Yuan C. Lee Johns Hopkins University
George K. Lewis
George K. Lewis University of Maryland, Baltimore
Alan S. Cross
Alan S. Cross University of Maryland, Baltimore
Dennis R. Burton
Dennis R. Burton Scripps Research Institute
Kenji Yamamoto
Kenji Yamamoto Ishikawa Prefectural University
Marie Pancera
Marie Pancera Fred Hutchinson Cancer Research Center
Yongping Yang
Yongping Yang National Institutes of Health
Saul Roseman
Saul Roseman Johns Hopkins University
Robert R. Redfield
Robert R. Redfield Centers for Disease Control and Prevention
Gerardo R. Vasta
Gerardo R. Vasta University of Maryland, Baltimore

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

For students studying Chemistry in the USA, exploring related disciplines can broaden career prospects. Fields like forensic science offer exciting opportunities where chemical knowledge is applied to legal investigations. Those interested can learn more about forensic careers, which often require specialized scientific training combined with law enforcement principles.

Many pursue online degree options to balance education with personal or professional commitments. Programs such as cost of criminal justice degree guide prospective students through tuition and fees, helping them plan financially for their education. Affordable and flexible programs are increasingly popular for those aiming to enter law-related fields.

For beginners or those seeking quicker entry into the workforce, online criminal justice associate degree programs provide foundational knowledge and skills. These programs offer excellent pathways into careers that intersect with chemistry, such as crime scene analysis and evidence handling.

Another complementary option is pursuing a paralegal degree. Paralegals support legal professionals by managing case research and documentation, where a background in sciences can be advantageous, especially in cases involving chemical evidence. Understanding the salary prospects tied to these degrees helps in making informed career decisions.

Best Scientists Citing Lai-Xi Wang

Trending Scientists