H-Index & Metrics Best Publications

H-Index & Metrics

Discipline name H-index Citations Publications World Ranking National Ranking
Chemistry D-index 48 Citations 6,661 126 World Ranking 9410 National Ranking 2700
Biology and Biochemistry D-index 57 Citations 10,050 161 World Ranking 6668 National Ranking 3078

Research.com Recognitions

Awards & Achievements

2014 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

What is he best known for?

The fields of study he is best known for:

  • Enzyme
  • Gene
  • Biochemistry

His primary areas of study are Biochemistry, Glycosylation, Glycan, Antibody and Stereochemistry. His research related to Glycosynthase, Glycoside hydrolase, Endoglycosidase, Mutant and Fragment crystallizable region might be considered part of Biochemistry. Lai-Xi Wang has included themes like Sialic acid, Glycoprotein and Enzyme in his Glycosylation study.

His study in Glycan is interdisciplinary in nature, drawing from both Mutagenesis and Antibody-dependent cell-mediated cytotoxicity. His Antibody study incorporates themes from Molecular biology, Antigen and Virology. The study incorporates disciplines such as Oxazoline, Oligosaccharide and Substrate in addition to Stereochemistry.

His most cited work include:

  • Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9 (694 citations)
  • Structural basis for diverse N-glycan recognition by HIV-1–neutralizing V1–V2–directed antibody PG16 (229 citations)
  • Chemoenzymatic Glycoengineering of Intact IgG Antibodies for Gain of Functions (208 citations)

What are the main themes of his work throughout his whole career to date?

His primary scientific interests are in Biochemistry, Glycan, Glycosylation, Glycoprotein and Antibody. His study in Endoglycosidase, Glycosynthase, Enzyme, Oligosaccharide and Mutant is done as part of Biochemistry. His work carried out in the field of Glycan brings together such families of science as Receptor and Mucor hiemalis.

His Glycosylation research incorporates themes from Carbohydrate conformation, Stereochemistry, Computational biology, Peptide and Glycoside hydrolase. His Glycoprotein research is multidisciplinary, incorporating perspectives in Mannose, Recombinant DNA and Immunogenicity. His Epitope study integrates concerns from other disciplines, such as Molecular biology, Immunogen and Virology.

He most often published in these fields:

  • Biochemistry (47.32%)
  • Glycan (38.05%)
  • Glycosylation (35.12%)

What were the highlights of his more recent work (between 2017-2021)?

  • Glycan (38.05%)
  • Glycosylation (35.12%)
  • Biochemistry (47.32%)

In recent papers he was focusing on the following fields of study:

Lai-Xi Wang focuses on Glycan, Glycosylation, Biochemistry, Antibody and Glycoprotein. He interconnects Hydrolase, Receptor, Antibody-dependent cell-mediated cytotoxicity and Binding site in the investigation of issues within Glycan. His research in Glycosylation intersects with topics in Virology, Function, Immunogenicity, Immunogen and Computational biology.

In his study, Galectin and Innate immune system is strongly linked to Effector, which falls under the umbrella field of Antibody. His work in the fields of Glycoprotein synthesis overlaps with other areas such as Extramural. His work deals with themes such as Streptococcus pyogenes and Glycoside hydrolase, which intersect with Endoglycosidase.

Between 2017 and 2021, his most popular works were:

  • Chemoenzymatic Methods for the Synthesis of Glycoproteins (71 citations)
  • Site-selective chemoenzymatic glycoengineering of Fab and Fc glycans of a therapeutic antibody (27 citations)
  • Site-selective chemoenzymatic glycoengineering of Fab and Fc glycans of a therapeutic antibody (27 citations)

In his most recent research, the most cited papers focused on:

  • Enzyme
  • Gene
  • DNA

Lai-Xi Wang mainly focuses on Glycan, Glycosylation, Antibody, Biochemistry and Glycoprotein. His study in Functional studies extends to Glycan with its themes. His Glycosylation research includes themes of Protein processing, Glycoprotein synthesis, Virology, Immunogenicity and Immunogen.

His studies in Antibody integrate themes in fields like Receptor, In vitro and Immune system. His research in Glycosynthase and Endoglycosidase are components of Biochemistry. Lai-Xi Wang combines subjects such as Post translational, Glycosyltransferase, Computational biology and Peptide with his study of Glycoprotein.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9

Jason S. McLellan;Marie Pancera;Chris Carrico;Jason Gorman.
Nature (2011)

846 Citations

Structural basis for diverse N-glycan recognition by HIV-1–neutralizing V1–V2–directed antibody PG16

Marie Pancera;Syed Shahzad-Ul-Hussan;Nicole A. Doria-Rose;Jason S. McLellan.
Nature Structural & Molecular Biology (2013)

291 Citations

Chemoenzymatic Glycoengineering of Intact IgG Antibodies for Gain of Functions

Wei Huang;John Giddens;Shu-Quan Fan;Christian Toonstra.
Journal of the American Chemical Society (2012)

254 Citations

Mutants of Mucor hiemalis Endo-β-N-acetylglucosaminidase Show Enhanced Transglycosylation and Glycosynthase-like Activities

Midori Umekawa;Wei Huang;Bing Li;Kiyotaka Fujita.
Journal of Biological Chemistry (2008)

236 Citations

Highly efficient endoglycosidase-catalyzed synthesis of glycopeptides using oligosaccharide oxazolines as donor substrates.

Bing Li;Ying Zeng;Steven Hauser;Haijing Song.
Journal of the American Chemical Society (2005)

213 Citations

Chemoenzymatic Synthesis and Fcγ Receptor Binding of Homogeneous Glycoforms of Antibody Fc Domain. Presence of a Bisecting Sugar Moiety Enhances the Affinity of Fc to FcγIIIa Receptor

Guozhang Zou;Hirofumi Ochiai;Wei Huang;Qiang Yang.
Journal of the American Chemical Society (2011)

202 Citations

Enzymatic transglycosylation for glycoconjugate synthesis.

Lai-Xi Wang;Wei Huang.
Current Opinion in Chemical Biology (2009)

187 Citations

A combined method for producing homogeneous glycoproteins with eukaryotic N-glycosylation

Flavio Schwarz;Wei Huang;Cishan Li;Benjamin L Schulz.
Nature Chemical Biology (2010)

187 Citations

Glycosynthases Enable a Highly Efficient Chemoenzymatic Synthesis of N-Glycoproteins Carrying Intact Natural N-Glycans

Wei Huang;Cishan Li;Bing Li;Midori Umekawa.
Journal of the American Chemical Society (2009)

174 Citations

Binding of high-mannose-type oligosaccharides and synthetic oligomannose clusters to human antibody 2G12: implications for HIV-1 vaccine design.

Lai-Xi Wang;Jiahong Ni;Suddham Singh;Hengguang Li.
Chemistry & Biology (2004)

168 Citations

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Best Scientists Citing Lai-Xi Wang

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Dennis R. Burton

Scripps Research Institute

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Peter D. Kwong

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John R. Mascola

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David C. Montefiori

Duke University

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Michel C. Nussenzweig

Rockefeller University

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University of the Witwatersrand

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Michael S. Seaman

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Penny L. Moore

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Susan Zolla-Pazner

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