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D-Index & Metrics

Biology and Biochemistry

D-Index
60
Citations
10636
World Ranking
12148
National Ranking
831

Overview

Kenji Yamamoto is affiliated with Ishikawa Prefectural University in Japan and has a research focus spanning medicine and biochemistry, genetics, and molecular biology. Their work extends through various subfields including molecular biology, neurology, food science, nutrition and dietetics, and oncology.

The scientist's body of research includes investigations across several main topics: probiotics and fermented foods, glycosylation and glycoproteins research, gut microbiota and health, microbial metabolites in food biotechnology, carbohydrate chemistry and synthesis, enzyme production and characterization, and pain management and opioid use.

Selected recent publications demonstrate the range of disciplines and topics covered. These include:

  • Safety and efficacy of rituximab in neuromyelitis optica spectrum disorders (RIN-1 study): a multicentre, randomised, double-blind, placebo-controlled trial (2020, The Lancet Neurology)
  • Host metabolic benefits of prebiotic exopolysaccharides produced by Leuconostoc mesenteroides (2023, Gut Microbes)
  • Mucin glycans and their degradation by gut microbiota (2023, Glycoconjugate Journal)
  • Compassionate open-label use of rituximab following a randomised clinical trial against neuromyelitis optica (RIN-2 study): B cell monitoring-based administration (2022, Multiple Sclerosis and Related Disorders)
  • Role of Lipoteichoic Acid from the Genus Apilactobacillus in Inducing a Strong IgA Response (2022, Applied and Environmental Microbiology)

Frequent coauthors collaborating with Kenji Yamamoto include:

  • Chiaki Matsuzaki
  • Hideyuki Sawada
  • Tomoko Oeda
  • Keiko Hisa
  • Tai-Ying Chiou

Their research has been published repeatedly in several key venues: Journal of Anesthesia, Gut Microbes, Applied and Environmental Microbiology, Carbohydrate Research, and The Lancet Neurology.

Best Publications

  • Physiology of Consumption of Human Milk Oligosaccharides by Infant Gut-associated Bifidobacteria

    Sadaki Asakuma;Emi Hatakeyama;Tadasu Urashima;Erina Yoshida

  • Molecular Cloning and Characterization of Bifidobacterium bifidum 1,2-α-l-Fucosidase (AfcA), a Novel Inverting Glycosidase (Glycoside Hydrolase Family 95)

    Takane Katayama;Akiko Sakuma;Takatoshi Kimura;Yutaka Makimura

  • Mutants of Mucor hiemalis Endo-β-N-acetylglucosaminidase Show Enhanced Transglycosylation and Glycosynthase-like Activities

    Midori Umekawa;Wei Huang;Bing Li;Kiyotaka Fujita

  • Two distinct α-l-fucosidases from Bifidobacterium bifidum are essential for the utilization of fucosylated milk oligosaccharides and glycoconjugates

    Hisashi Ashida;Akiko Miyake;Masashi Kiyohara;Jun Wada

  • Bifidobacterium bifidum Lacto-N-Biosidase, a Critical Enzyme for the Degradation of Human Milk Oligosaccharides with a Type 1 Structure

    Jun Wada;Jun Wada;Takuro Ando;Masashi Kiyohara;Hisashi Ashida

  • Total biosynthesis of opiates by stepwise fermentation using engineered Escherichia coli

    Akira Nakagawa;Eitaro Matsumura;Takashi Koyanagi;Takane Katayama

  • Synthesis of a Glycopeptide Containing Oligosaccharides: Chemoenzymatic Synthesis of Eel Calcitonin Analogues Having Natural N-Linked Oligosaccharides

    Mamoru Mizuno;Katsuji Haneda;Reiko Iguchi;Ikuyo Muramoto

  • Carbohydrate Binding Specificity of a Fucose-specific Lectin from Aspergillus oryzae: A NOVEL PROBE FOR CORE FUCOSE

    Kengo Matsumura;Katsuya Higashida;Hiroki Ishida;Yoji Hata

  • Identification and Molecular Cloning of a Novel Glycoside Hydrolase Family of Core 1 Type O-Glycan-specific Endo-α-N-acetylgalactosaminidase from Bifidobacterium longum

    Kiyotaka Fujita;Fusako Oura;Noriko Nagamine;Takane Katayama

  • Glycosynthases Enable a Highly Efficient Chemoenzymatic Synthesis of N-Glycoproteins Carrying Intact Natural N-Glycans

    Wei Huang;Cishan Li;Bing Li;Midori Umekawa

  • Glycosylation engineering of therapeutic IgG antibodies: challenges for the safety, functionality and efficacy

    Yusuke Mimura;Toshihiko Katoh;Radka Saldova;Roisin O’Flaherty

  • A novel disaccharide substrate having 1,2-oxazoline moiety for detection of transglycosylating activity of endoglycosidases.

    Masaya Fujita;Shin ichiro Shoda;Katsuji Haneda;Toshiyuki Inazu

  • Purification and characterization of a protease-resistant cellulase from Aspergillus niger

    Shunichi Akiba;Yoshiharu Kimura;Kenji Yamamoto;Hidehiko Kumagai

  • Chemoenzymatic synthesis and application of glycopolymers containing multivalent sialyloligosaccharides with a poly(L-glutamic acid) backbone for inhibition of infection by influenza viruses.

    Kazuhide Totani;Takeshi Kubota;Takao Kuroda;Takeomi Murata

  • Efficient Glycosynthase Mutant Derived from Mucor hiemalis Endo-β-N-acetylglucosaminidase Capable of Transferring Oligosaccharide from Both Sugar Oxazoline and Natural N-Glycan

    Midori Umekawa;Cishan Li;Takayuki Higashiyama;Wei Huang

  • Sharing of human milk oligosaccharides degradants within bifidobacterial communities in faecal cultures supplemented with Bifidobacterium bifidum.

    Aina Gotoh;Toshihiko Katoh;Mikiyasu Sakanaka;Yiwei Ling

  • Bifidobacterium longum subsp. infantis uses two different β-galactosidases for selectively degrading type-1 and type-2 human milk oligosaccharides

    Erina Yoshida;Haruko Sakurama;Masashi Kiyohara;Masahiro Nakajima

  • Structural Basis of the Catalytic Reaction Mechanism of Novel 1,2-α-L-Fucosidase from Bifidobacterium bifidum

    Masamichi Nagae;Atsuko Tsuchiya;Takane Katayama;Kenji Yamamoto

  • Cooperation of β-galactosidase and β-N-acetylhexosaminidase from bifidobacteria in assimilation of human milk oligosaccharides with type 2 structure

    Mika Miwa;Tomohiro Horimoto;Masashi Kiyohara;Masashi Kiyohara;Takane Katayama

  • An exo-α-sialidase from bifidobacteria involved in the degradation of sialyloligosaccharides in human milk and intestinal glycoconjugates

    Masashi Kiyohara;Kana Tanigawa;Thida Chaiwangsri;Takane Katayama

Frequent Co-Authors

Hidehiko Kumagai
Hidehiko Kumagai Ishikawa Prefectural University
Shinya Fushinobu
Shinya Fushinobu University of Tokyo
Motomitsu Kitaoka
Motomitsu Kitaoka Niigata University
Hirofumi Shoun
Hirofumi Shoun University of Tokyo
Hideyuki Suzuki
Hideyuki Suzuki Kyoto Institute of Technology
Bunzo Mikami
Bunzo Mikami Kyoto University
Lai-Xi Wang
Lai-Xi Wang University of Maryland, College Park
Wataru Hashimoto
Wataru Hashimoto Kyoto University
Masahira Hattori
Masahira Hattori Waseda University
Kazuhiro Aoki
Kazuhiro Aoki National Institutes of Natural Sciences

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