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Immunology

D-Index
58
Citations
17442
World Ranking
3470
National Ranking
1611

Overview

George K. Lewis is affiliated with the University of Maryland, Baltimore in the United States. Their research primarily spans several interconnected domains within biomedical sciences, including medicine, immunology, microbiology, and molecular biology.

The main fields of study associated with their work are:

  • Medicine
  • Immunology and Microbiology
  • Biochemistry, Genetics and Molecular Biology

Within these broader fields, their subfields of focus include:

  • Infectious Diseases
  • Radiology, Nuclear Medicine and Imaging
  • Molecular Biology
  • Virology
  • Immunology

The scientist's research concentrates on several main topics, reflecting the biomedical and immunological nature of their work:

  • Monoclonal and Polyclonal Antibodies Research
  • HIV Research and Treatment
  • SARS-CoV-2 and COVID-19 Research
  • T-cell and B-cell Immunology
  • Glycosylation and Glycoproteins Research
  • COVID-19 Impact on Reproduction
  • SARS-CoV-2 detection and testing

George K. Lewis has multiple recent papers published in a range of scientific journals. Selected works include:

  • "Performance of nucleocapsid and spike-based SARS-CoV-2 serologic assays" (2020) in PLoS ONE
  • "Analysis of a Therapeutic Antibody Cocktail Reveals Determinants for Cooperative and Broad Ebolavirus Neutralization" (2020) in Immunity
  • "Antigen-Induced Allosteric Changes in a Human IgG1 Fc Increase Low-Affinity Fcγ Receptor Binding" (2020) in Structure
  • "Specificity and Performance of Nucleocapsid and Spike-based SARS-CoV-2 Serologic Assays" (2020) in bioRxiv (Cold Spring Harbor Laboratory)
  • "Defining rules governing recognition and Fc-mediated effector functions to the HIV-1 co-receptor binding site" (2020) in BMC Biology

The frequent co-authors of George K. Lewis consist of a group of researchers with whom they have collaborated extensively. These include:

  • Mohammad M. Sajadi
  • Anthony L. DeVico
  • Zahra Rikhtegaran Tehrani
  • Robin Flinko
  • William D. Tolbert

Their publications have appeared predominantly in the following venues:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Frontiers in Immunology
  • PLoS ONE
  • Structure
  • mBio

The body of work by George K. Lewis addresses critical aspects of infectious diseases, antibody responses, and viral immunology, particularly emphasizing SARS-CoV-2 and HIV.

Best Publications

  • Isolation of monoclonal antibodies specific for human c-myc proto-oncogene product.

    G I Evan;G K Lewis;G Ramsay;J M Bishop

  • Isolation of monoclonal antibodies specific for human c-myc proto-oncogene product

    Unknown

  • Immune-Correlates Analysis of an HIV-1 Vaccine Efficacy Trial

    Barton F. Haynes;Peter B. Gilbert;M. Juliana McElrath;Susan Zolla-Pazner

  • Antibody-Dependent Cellular Cytotoxicity-Mediating Antibodies from an HIV-1 Vaccine Efficacy Trial Target Multiple Epitopes and Preferentially Use the VH1 Gene Family

    Mattia Bonsignori;Justin Pollara;M. Anthony Moody;Michael D. Alpert

  • Live-attenuated Salmonella as a prototype vaccine vector for passenger immunogens in humans: are we there yet?

    George K Lewis

  • An HIV-1 transgenic rat that develops HIV-related pathology and immunologic dysfunction

    W. Reid;M. Sadowska;F. Denaro;S. Rao

  • Interaction with Cellular CD4 Exposes HIV-1 Envelope Epitopes Targeted by Antibody-Dependent Cell-Mediated Cytotoxicity

    Maxime Veillette;Anik Désormeaux;Halima Medjahed;Nour-Elhouda Gharsallah

  • Epitope Mapping and Topology of Baculovirus-Expressed HIV-1 gp160 Determined with a Panel of Murine Monoclonal Antibodies

    Yusuf Hakan Abacioglu;Timothy R. Fouts;Jon D. Laman;Eric Claassen

  • Persistence of HIV-1 structural proteins and glycoproteins in lymph nodes of patients under highly active antiretroviral therapy

    Mikulas Popovic;Klara Tenner-Racz;Colleen Pelser;Hans-Jurgen Stellbrink

  • Phage display of intact domains at high copy number: A system based on SOC, the small outer capsid protein of bacteriophage T4

    Z J Ren;G K Lewis;P T Wingfield;E G Locke

  • Recent advances with recombinant bacterial vaccine vectors

    Mohamed T Shata;Liljana Stevceva;Simon Agwale;George K Lewis

  • Diverse specificity and effector function among human antibodies to HIV-1 envelope glycoprotein epitopes exposed by CD4 binding

    Yongjun Guan;Marzena Pazgier;Mohammad M. Sajadi;Roberta Kamin-Lewis

  • Actin polymerization and pseudopod reorganization accompany anti-CD3-induced growth arrest in Jurkat T cells

    M V Parsey;G K Lewis

  • Method for introducing and expressing genes in animal cells, and live invasive bacterial vectors for use in the same

    Robert J. Powell;George K. Lewis;David M. Hone

  • Baculovirus-Derived Human Immunodeficiency Virus Type 1 Virus-Like Particles Activate Dendritic Cells and Induce Ex Vivo T-Cell Responses

    L. Buonaguro;M. L. Tornesello;M. Tagliamonte;R. C. Gallo

  • Expression and Characterization of a Single-Chain Polypeptide Analogue of the Human Immunodeficiency Virus Type 1 gp120-CD4 Receptor Complex

    Timothy R. Fouts;Robert Tuskan;Karla Godfrey;Marvin Reitz

  • Immunochemical analysis of the gp120 surface glycoprotein of human immunodeficiency virus type 1: probing the structure of the C4 and V4 domains and the interaction of the C4 domain with the V3 loop.

    J P Moore;M Thali;B A Jameson;F Vignaux

  • Variant-specific monoclonal and group-specific polyclonal human immunodeficiency virus type 1 neutralizing antibodies raised with synthetic peptides from the gp120 third variable domain.

    J.D. Laman;M.M. Schellekens;Y.H. Abacioglu;G.K. Lewis

  • Balance of cellular and humoral immunity determines the level of protection by HIV vaccines in rhesus macaque models of HIV infection

    Timothy R. Fouts;Kenneth Bagley;Ilia J. Prado;Kathryn L. Bobb

  • Antibody persistence and T-cell balance: Two key factors confronting HIV vaccine development

    George K. Lewis;Anthony L. DeVico;Robert C. Gallo

  • Immunological evidence for interactions between the first, second, and fifth conserved domains of the gp120 surface glycoprotein of human immunodeficiency virus type 1.

    J P Moore;R L Willey;G K Lewis;J Robinson

  • Structural Definition of an Antibody-Dependent Cellular Cytotoxicity Response Implicated in Reduced Risk for HIV-1 Infection.

    Priyamvada Acharya;William D. Tolbert;Neelakshi Gohain;Xueji Wu

  • Mucosal and systemic HIV-1 Env-specific CD8(+) T-cells develop after intragastric vaccination with a Salmonella Env DNA vaccine vector.

    Mohamed T. Shata;Marvin S. Reitz;Anthony L. DeVico;George K. Lewis

Frequent Co-Authors

Anthony L. DeVico
Anthony L. DeVico University of Maryland, Baltimore
Robert C. Gallo
Robert C. Gallo University of South Florida
Andrés Finzi
Andrés Finzi University of Montreal
Robert R. Redfield
Robert R. Redfield Centers for Disease Control and Prevention
Guido Ferrari
Guido Ferrari Duke University
Franco M. Buonaguro
Franco M. Buonaguro MRC Laboratory of Molecular Biology
Ranajit Pal
Ranajit Pal Advanced Bioscience Laboratories (United States)
Luigi Buonaguro
Luigi Buonaguro Fondazione IRCCS Istituto Nazionale dei Tumori
David C. Montefiori
David C. Montefiori Duke University
Lai-Xi Wang
Lai-Xi Wang University of Maryland, College Park

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