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Bernhard Bettler

Bernhard Bettler

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Biology and Biochemistry
Switzerland
2023

D-Index & Metrics

Biology and Biochemistry

D-Index
89
Citations
29627
World Ranking
2547
National Ranking
56

Research.com Recognitions

  • 2023 - Research.com Biology and Biochemistry in Switzerland Leader Award

Overview

Bernhard Bettler is affiliated with the University of Basel in Switzerland. Their research output spans across fields such as Biochemistry, Genetics and Molecular Biology, as well as Neuroscience. Prominent subfields of study include Molecular Biology, Cellular and Molecular Neuroscience, Genetics, Developmental Neuroscience, and Cognitive Neuroscience.

The main topics Bernhard Bettler focuses on are:

  • Neuroscience and Neuropharmacology Research
  • Receptor Mechanisms and Signaling
  • Nicotinic Acetylcholine Receptors Study
  • Ion channel regulation and function
  • Neurotransmitter Receptor Influence on Behavior
  • Genetics and Neurodevelopmental Disorders
  • RNA and protein synthesis mechanisms

Their frequent co-authors include Martin Gassmann, Thorsten Fritzius, Diego Fernández-Fernández, Michał Stawarski, and Pascal D. Rem. This collaboration pattern highlights a consistent engagement in multidisciplinary research teams.

Publication venues where Bernhard Bettler has a significant presence are:

  • IUPHAR/BPS Guide to Pharmacology CITE
  • bioRxiv (Cold Spring Harbor Laboratory)
  • British Journal of Pharmacology
  • eLife
  • Neuropharmacology

Key recent papers authored or co-authored by Bernhard Bettler include:

  • "THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: G protein-coupled receptors" (2021, British Journal of Pharmacology)
  • "The Concise Guide to PHARMACOLOGY 2023/24: G protein-coupled receptors" (2023, British Journal of Pharmacology)
  • "Targeting receptor complexes: a new dimension in drug discovery" (2020, Nature Reviews Drug Discovery)
  • "Impaired bidirectional communication between interneurons and oligodendrocyte precursor cells affects social cognitive behavior" (2022, Nature Communications)
  • "GABAB receptor auxiliary subunits modulate Cav2.3-mediated release from medial habenula terminals" (2021, eLife)

Best Publications

  • GABAB-RECEPTOR SUBTYPES ASSEMBLE INTO FUNCTIONAL HETEROMERIC COMPLEXES

    Klemens Kaupmann;Barbara Malitschek;Valerie Schuler;Jakob Heid

  • Expression cloning of GABA(B) receptors uncovers similarity to metabotropic glutamate receptors.

    Klemens Kaupmann;Katharina Huggel;Jakob Heid;Peter J. Flor

  • Molecular Structure and Physiological Functions of GABAB Receptors

    Bernhard Bettler;Klemens Kaupmann;Johannes Mosbacher;Martin Gassmann

  • Cloning of a novel glutamate receptor subunit, GluR5 : expression in the nervous system during development

    Bernhard Bettler;Jim Boulter;Irm Hermans-Borgmeyer;Anne O'Shea-Greenfield

  • Cloning of a cDNA for a glutamate receptor subunit activated by kainate but not AMPA.

    Jan Egebjerg;Bernhard Bettler;Irm Hermans-Borgmeyer;Stephen Heinemann

  • International Union of Pharmacology. XXXIII. Mammalian γ-Aminobutyric AcidB Receptors: Structure and Function

    N. G. Bowery;B. Bettler;W. Froestl;J. P. Gallagher

  • Review: neurotransmitter receptors. II. AMPA and kainate receptors.

    B. Bettler;C. Mulle

  • Epilepsy, hyperalgesia, impaired memory, and loss of pre- and postsynaptic GABA(B) responses in mice lacking GABA(B(1))

    Valérie Schuler;Christian Lüscher;Christophe Blanchet;Norman Klix

  • Altered synaptic physiology and reduced susceptibility to kainate-induced seizures in GluR6-deficient mice

    Christophe Mulle;Andreas Sailer;Isabel Pérez-Otaño;Heather Dickinson-Anson

  • Agonist selectivity of glutamate receptors is specified by two domains structurally related to bacterial amino acid-binding proteins

    Yael Stern-Bach;Bernhard Bettler;Melissa Hartley;Paul O. Sheppard

  • The Concise Guide to PHARMACOLOGY 2017/18: Overview

    Stephen P. H. Alexander;Eamonn Kelly;Neil V. Marrion;John A. Peters

  • Cloning of a putative glutamate receptor: a low affinity kainate-binding subunit.

    Bernhard Bettler;Jan Egebjerg;Geeta Sharma;Geeta Sharma;Gerlinde Pecht

  • Allosteric interactions between GB1 and GB2 subunits are required for optimal GABAB receptor function

    Thierry Galvez;Béatrice Duthey;Julie Kniazeff;Jaroslav Blahos

  • GABAB receptors - the first 7TM heterodimers.

    Fiona H Marshall;Kenneth A Jones;Klemens Kaupmann;Bernhard Bettler

  • THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: G protein-coupled receptors

    Stephen P.H. Alexander;Arthur Christopoulos;Anthony P. Davenport;Eamonn Kelly

  • Regulation of neuronal GABA B receptor functions by subunit composition

    Martin Gassmann;Bernhard Bettler

  • Positive allosteric modulation of native and recombinant gamma-aminobutyric acid(B) receptors by 2,6-Di-tert-butyl-4-(3-hydroxy-2,2-dimethyl-propyl)-phenol (CGP7930) and its aldehyde analog CGP13501.

    Stephan Urwyler;Johannes Mosbacher;Kurt Lingenhoehl;Jakob Heid

  • C-terminal interaction is essential for surface trafficking but not for heteromeric assembly of GABA(b) receptors.

    Adriana Pagano;Giorgio Rovelli;Johannes Mosbacher;Tania Lohmann;Tania Lohmann

  • Differential Compartmentalization and Distinct Functions of GABAB Receptor Variants

    Réjan Vigot;Samuel Barbieri;Hans Bräuner-Osborne;Rostislav Turecek;Rostislav Turecek

  • Native GABA B receptors are heteromultimers with a family of auxiliary subunits

    Jochen Schwenk;Michaela Metz;Gerd Zolles;Rostislav Turecek;Rostislav Turecek

Frequent Co-Authors

Martin Gassmann
Martin Gassmann University of Basel
Klemens Kaupmann
Klemens Kaupmann Novartis (Switzerland)
John F. Cryan
John F. Cryan University College Cork
Ryuichi Shigemoto
Ryuichi Shigemoto Institute of Science and Technology Austria
Wolfgang Froestl
Wolfgang Froestl AC Immune (Switzerland)
Stephen F. Heinemann
Stephen F. Heinemann Salk Institute for Biological Studies
Jean-Philippe Pin
Jean-Philippe Pin University of Montpellier
Michael Hollmann
Michael Hollmann Ruhr University Bochum
Akos Kulik
Akos Kulik University of Freiburg
Laurent Prézeau
Laurent Prézeau University of Montpellier

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