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Ralf Jockers

Ralf Jockers

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Biology and Biochemistry
France
2023

D-Index & Metrics

Biology and Biochemistry

D-Index
71
Citations
16643
World Ranking
6712
National Ranking
202

Research.com Recognitions

  • 2023 - Research.com Biology and Biochemistry in France Leader Award

Overview

Ralf Jockers is affiliated with Inserm in France and has contributed extensively to the fields of neuroscience, biochemistry, genetics, molecular biology, and medicine. Their research spans multiple subfields, including molecular biology, endocrine and autonomic systems, cellular and molecular neuroscience, physiology, and endocrinology, diabetes, and metabolism.

The scientist's research topics primarily focus on circadian rhythm and melatonin, receptor mechanisms and signaling, neuropeptides and animal physiology, photoreceptor and optogenetics research, diabetes treatment and management, pancreatic function and diabetes, and biochemical analysis and sensing techniques.

Jockers has published multiple recent papers, including:

  • THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: G protein-coupled receptors (2021) in British Journal of Pharmacology
  • The Concise Guide to PHARMACOLOGY 2023/24: G protein-coupled receptors (2023) in British Journal of Pharmacology
  • Leptin brain entry via a tanycytic LepR-EGFR shuttle controls lipid metabolism and pancreas function (2021) in Nature Metabolism
  • Genetic and biased agonist-mediated reductions in β-arrestin recruitment prolong cAMP signaling at glucagon family receptors (2020) in Journal of Biological Chemistry
  • Melatonin: Facts, Extrapolations and Clinical Trials (2023) in Biomolecules

Frequent co-authors collaborating with Jockers include Erika Cecon, Julie Dam, Atsuro Oishi, Florence Gbahou, and Vincent Prévot.

The primary venues for Jockers's publications are:

  • Journal of Pineal Research
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Frontiers in Endocrinology
  • Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature
  • Methods in molecular biology

Jockers also has a book publication titled Melatonin, released in 2022 by Springer Science+Business Media.

Best Publications

  • G Protein–Coupled Receptor Oligomerization Revisited: Functional and Pharmacological Perspectives

    Sergi Ferré;Vicent Casadó;Lakshmi A. Devi;Marta Filizola

  • Hypothalamic tanycytes are an ERK-gated conduit for leptin into the brain.

    Eglantine Balland;Julie Dam;Fanny Langlet;Emilie Caron

  • Dual role of mitochondria in producing melatonin and driving GPCR signaling to block cytochrome c release

    Yalikun Suofu;Wei Li;Wei Li;Frédéric G. Jean-Alphonse;Jiaoying Jia

  • THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: G protein-coupled receptors

    Stephen P.H. Alexander;Arthur Christopoulos;Anthony P. Davenport;Eamonn Kelly

  • Update on melatonin receptors: IUPHAR Review 20.

    Ralf Jockers;Ralf Jockers;Ralf Jockers;Philippe Delagrange;Margarita L. Dubocovich;Regina P. Markus

  • Rare MTNR1B variants impairing melatonin receptor 1B function contribute to type 2 diabetes

    Amélie Bonnefond;Amélie Bonnefond;Nathalie Clément;Nathalie Clément;Nathalie Clément;Katherine Fawcett;Loïc Yengo;Loïc Yengo

  • Oxytocin and vasopressin V1a and V2 receptors form constitutive homo- and heterodimers during biosynthesis.

    Sonia Terrillon;Thierry Durroux;Bernard Mouillac;Andreas Breit

  • The orphan GPR50 receptor specifically inhibits MT1 melatonin receptor function through heterodimerization

    Angélique Levoye;Julie Dam;Mohammed A Ayoub;Jean-Luc Guillaume

  • MONITORING OF LIGAND-INDEPENDENT DIMERIZATION AND LIGAND- INDUCED CONFORMATIONAL CHANGES OF MELATONIN RECEPTORS IN LIVING CELLS BY BIOLUMINESCENCE RESONANCE ENERGY TRANSFER

    Mohammed A. Ayoub;Cyril Couturier;Estelle Lucas-Meunier;Stephane Angers

  • Dual signaling of human Mel1a melatonin receptors via G(i2), G(i3), and G(q/11) proteins.

    L Brydon;F Roka;L Petit;P de Coppet

  • Melatonin receptors, heterodimerization, signal transduction and binding sites: what's new?

    R Jockers;R Jockers;P Maurice;P Maurice;J A Boutin;P Delagrange

  • The use of resonance energy transfer in high-throughput screening: BRET versus FRET

    Nicolas Boute;Ralf Jockers;Tarik Issad

  • Decreased MT1 melatonin receptor expression in the suprachiasmatic nucleus in aging and Alzheimer's disease.

    Ying-Hui Wu;Jiang-Ning Zhou;Joop Van Heerikhuize;Ralf Jockers

  • Reduced hippocampal MT2 melatonin receptor expression in Alzheimer's disease.

    Egemen Savaskan;Mohammed A. Ayoub;Rivka Ravid;Debora Angeloni

  • Preferential Formation of MT1/MT2 Melatonin Receptor Heterodimers with Distinct Ligand Interaction Properties Compared with MT2 Homodimers

    Mohammed A. Ayoub;Angélique Levoye;Philippe Delagrange;Ralf Jockers

  • Melatonin in type 2 diabetes mellitus and obesity

    Angeliki Karamitri;Angeliki Karamitri;Angeliki Karamitri;Ralf Jockers;Ralf Jockers;Ralf Jockers

  • Functional expression of MT2 (Mel1b) melatonin receptors in human PAZ6 adipocytes.

    L Brydon;L Petit;P Delagrange;A D Strosberg

  • Melatonin receptors: molecular pharmacology and signalling in the context of system bias

    Erika Cecon;Erika Cecon;Erika Cecon;Atsuro Oishi;Atsuro Oishi;Atsuro Oishi;Ralf Jockers;Ralf Jockers;Ralf Jockers

  • The BRET technology and its application to screening assays.

    Johan Bacart;Caroline Corbel;Ralf Jockers;Ralf Jockers;Stéphane Bach

  • Distribution of MT1 melatonin receptor immunoreactivity in the human hypothalamus and pituitary gland: colocalization of MT1 with vasopressin, oxytocin, and corticotropin-releasing hormone.

    Ying-Hui Wu;Jiang-Ning Zhou;Rawien Balesar;Unga Unmehopa

Frequent Co-Authors

Philippe Delagrange
Philippe Delagrange Centre national de la recherche scientifique, CNRS
Philippe Froguel
Philippe Froguel Imperial College London
Arthur Donny Strosberg
Arthur Donny Strosberg Scripps Research Institute
Stefano Marullo
Stefano Marullo Université Paris Cité
Michel Bouvier
Michel Bouvier University of Montreal
Vincent Prevot
Vincent Prevot University of Lille
Peter J. Morgan
Peter J. Morgan University of Aberdeen
A. Donny Strosberg
A. Donny Strosberg Université Paris Cité
Jean A. Boutin
Jean A. Boutin Institut de Recherches Internationales Servier
Rolf D. Schmid
Rolf D. Schmid University of Stuttgart

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