Ralf Jockers mainly focuses on Receptor, G protein-coupled receptor, Melatonin, Endocrinology and Internal medicine. His Receptor research is classified as research in Biochemistry. His work deals with themes such as Biophysics, Protomer and G protein, which intersect with G protein-coupled receptor.
His Melatonin study combines topics from a wide range of disciplines, such as Central nervous system, Neuroprotection and Cell biology. His work in Endocrinology tackles topics such as Genetics which are related to areas like Type 2 diabetes. In his work, Ganglion and Retina is strongly intertwined with Retinal, which is a subfield of Internal medicine.
Ralf Jockers focuses on Receptor, Melatonin, G protein-coupled receptor, Endocrinology and Internal medicine. His work carried out in the field of Receptor brings together such families of science as Signal transduction, Cell biology and Bioinformatics. The Signal transduction study combines topics in areas such as Neuroscience and Membrane protein.
Ralf Jockers interconnects Pharmacology and Circadian rhythm in the investigation of issues within Melatonin. In G protein-coupled receptor, Ralf Jockers works on issues like Biophysics, which are connected to Förster resonance energy transfer. His studies in Type 2 diabetes integrate themes in fields like Genome-wide association study and Melatonin receptor 1B.
Ralf Jockers focuses on Receptor, Melatonin, G protein-coupled receptor, Melatonin receptor and Cell biology. His research integrates issues of Endocrinology, Signal transduction and Glucose homeostasis in his study of Receptor. His Melatonin research includes themes of Diabetes mellitus, Pharmacology, Bioinformatics and Circadian rhythm.
His G protein-coupled receptor research incorporates themes from Integral membrane protein, Biophysics, Orphan receptor, Protein structure and Melatonin binding. His study in Melatonin receptor is interdisciplinary in nature, drawing from both GPR62, Proximity ligation assay and Ligand. Ralf Jockers has researched Cell biology in several fields, including HEK 293 cells, Inverse agonist and Biochemistry.
His primary scientific interests are in Melatonin, G protein-coupled receptor, Receptor, Melatonin receptor and Cell biology. His Melatonin study deals with the bigger picture of Internal medicine. His G protein-coupled receptor study is concerned with Signal transduction in general.
The various areas that Ralf Jockers examines in his Receptor study include Cytochrome c, Intracellular organelle and Obesity. His studies deal with areas such as Type 2 diabetes, Pineal gland and Pharmacology as well as Melatonin receptor. His Calcium signaling, Mitochondrion and G protein study in the realm of Cell biology connects with subjects such as Endogenous agonist.
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G Protein–Coupled Receptor Oligomerization Revisited: Functional and Pharmacological Perspectives
Sergi Ferré;Vicent Casadó;Lakshmi A. Devi;Marta Filizola.
Pharmacological Reviews (2014)
Hypothalamic tanycytes are an ERK-gated conduit for leptin into the brain.
Eglantine Balland;Julie Dam;Fanny Langlet;Emilie Caron.
Cell Metabolism (2014)
Oxytocin and vasopressin V1a and V2 receptors form constitutive homo- and heterodimers during biosynthesis.
Sonia Terrillon;Sonia Terrillon;Thierry Durroux;Bernard Mouillac;Andreas Breit.
Molecular Endocrinology (2003)
Rare MTNR1B variants impairing melatonin receptor 1B function contribute to type 2 diabetes
Amélie Bonnefond;Amélie Bonnefond;Nathalie Clément;Nathalie Clément;Nathalie Clément;Katherine Fawcett;Loïc Yengo;Loïc Yengo.
Nature Genetics (2012)
Dual signaling of human Mel1a melatonin receptors via G(i2), G(i3), and G(q/11) proteins.
L Brydon;F Roka;L Petit;P de Coppet.
Molecular Endocrinology (1999)
MONITORING OF LIGAND-INDEPENDENT DIMERIZATION AND LIGAND- INDUCED CONFORMATIONAL CHANGES OF MELATONIN RECEPTORS IN LIVING CELLS BY BIOLUMINESCENCE RESONANCE ENERGY TRANSFER
Mohammed A. Ayoub;Cyril Couturier;Estelle Lucas-Meunier;Stephane Angers.
Journal of Biological Chemistry (2002)
The use of resonance energy transfer in high-throughput screening: BRET versus FRET
Nicolas Boute;Ralf Jockers;Tarik Issad.
Trends in Pharmacological Sciences (2002)
The orphan GPR50 receptor specifically inhibits MT1 melatonin receptor function through heterodimerization
Angélique Levoye;Julie Dam;Mohammed A Ayoub;Jean‐Luc Guillaume.
The EMBO Journal (2006)
Melatonin receptors, heterodimerization, signal transduction and binding sites: what's new?
R Jockers;R Jockers;P Maurice;P Maurice;J A Boutin;P Delagrange.
British Journal of Pharmacology (2008)
Update on melatonin receptors: IUPHAR Review 20.
Ralf Jockers;Ralf Jockers;Ralf Jockers;Philippe Delagrange;Margarita L. Dubocovich;Regina P. Markus.
British Journal of Pharmacology (2016)
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