World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
62
Citations
18798
World Ranking
10592
National Ranking
4602

Research.com Recognitions

  • 2015 - Fellow of the Indian National Academy of Engineering (INAE)

Overview

Niren Murthy is affiliated with the University of California, Berkeley in the United States and engages primarily in research within Biochemistry, Genetics, and Molecular Biology, as well as Medicine. Their work spans several subfields including Molecular Biology, Genetics, Infectious Diseases, Epidemiology, and Molecular Medicine.

Key research topics addressed by the scientist include:

  • RNA Interference and Gene Delivery
  • CRISPR and Genetic Engineering
  • Virus-based gene therapy research
  • Advanced biosensing and bioanalysis techniques
  • RNA regulation and disease
  • Antibiotic Resistance in Bacteria
  • SARS-CoV-2 and COVID-19 Research

Niren Murthy has contributed to multiple scientific papers with notable recent publications such as:

  • The delivery challenge: fulfilling the promise of therapeutic genome editing, 2020, Nature Biotechnology
  • Recent advances in organic near-infrared ratiometric small-molecule fluorescent probes, 2023, Coordination Chemistry Reviews
  • The NIH Somatic Cell Genome Editing program, 2021, Nature
  • Lung and liver editing by lipid nanoparticle delivery of a stable CRISPR-Cas9 ribonucleoprotein, 2024, Nature Biotechnology
  • Non-viral strategies for delivering genome editing enzymes, 2020, Advanced Drug Delivery Reviews

Frequent collaborators include:

  • Hesong Han
  • Joachim Justad Røise
  • Jie Li
  • Maomao He
  • Teena Bajaj

The scientist's research has been published across several venues, with recurring contributions in:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • RSC Advances
  • Chemical Communications
  • Nature Biotechnology
  • Advanced Drug Delivery Reviews

Niren Murthy received recognition as a Fellow of the Indian National Academy of Engineering (INAE) in 2015.

Best Publications

  • Programming the magnitude and persistence of antibody responses with innate immunity.

    Sudhir Pai Kasturi;Ioanna Skountzou;Randy A. Albrecht;Dimitrios Koutsonanos

  • Dissolving polymer microneedle patches for influenza vaccination

    Sean P Sullivan;Dimitrios G Koutsonanos;Maria del Pilar Martin;Jeong Woo Lee

  • Nanoparticle delivery of Cas9 ribonucleoprotein and donor DNA in vivo induces homology-directed DNA repair

    Kunwoo Lee;Michael Conboy;Hyo Min Park;Fuguo Jiang

  • Orally delivered thioketal nanoparticles loaded with TNF-α–siRNA target inflammation and inhibit gene expression in the intestines

    D. Scott Wilson;Guillaume Dalmasso;Lixin Wang;Shanthi V. Sitaraman

  • Maleimide Cross‐Linked Bioactive PEG Hydrogel Exhibits Improved Reaction Kinetics and Cross‐Linking for Cell Encapsulation and In Situ Delivery

    Edward A. Phelps;Nduka O. Enemchukwu;Vincent F. Fiore;Jay C. Sy

  • In vivo imaging of hydrogen peroxide with chemiluminescent nanoparticles

    Dongwon Lee;Sirajud Khaja;Juan C. Velasquez-Castano;Madhuri Dasari

  • The design and synthesis of polymers for eukaryotic membrane disruption

    Niren Murthy;John R Robichaud;David A Tirrell;Patrick S Stayton

  • Detection of unamplified target genes via CRISPR–Cas9 immobilized on a graphene field-effect transistor

    Reza Hajian;Sarah Balderston;Thanhtra Tran;Tara deBoer

  • A macromolecular delivery vehicle for protein-based vaccines: Acid-degradable protein-loaded microgels

    Niren Murthy;Mingcheng Xu;Stephany Schuck;Jun Kunisawa

  • Toll-like receptor-mediated induction of type I interferon in plasmacytoid dendritic cells requires the rapamycin-sensitive PI(3)K-mTOR-p70S6K pathway

    Weiping Cao;Santhakumar Manicassamy;Hua Tang;Sudhir Pai Kasturi

  • A Novel Strategy for Encapsulation and Release of Proteins: Hydrogels and Microgels with Acid-Labile Acetal Cross-Linkers

    Niren Murthy;Yi X. Thng;Stephany Schuck;Ming C. Xu

  • 193 Orally Delivered Thioketal-Nanoparticles Loaded With TNFα-SiRNA Target Inflammation and Inhibit Gene Expression in the Intestines

    David S. Wilson;Guillaume Dalmasso;Lixin Wang;Shanthi V. Sitaraman

  • Really smart bioconjugates of smart polymers and receptor proteins

    Allan S. Hoffman;Patrick S. Stayton;Volga Bulmus;Guohua Chen

  • Minimally invasive protein delivery with rapidly dissolving polymer microneedles

    Sean P Sullivan;Niren Murthy;Mark R Prausnitz

  • Hydrocyanines: a class of fluorescent sensors that can image reactive oxygen species in cell culture, tissue, and in vivo

    Kousik Kundu;Sarah F. Knight;Nick Willett;Sungmun Lee

  • The T helper type 2 response to cysteine proteases requires dendritic cell–basophil cooperation via ROS-mediated signaling

    Hua Tang;Weiping Cao;Sudhir Pai Kasturi;Rajesh Ravindran

  • A new pH-responsive and glutathione-reactive, endosomal membrane-disruptive polymeric carrier for intracellular delivery of biomolecular drugs.

    Volga Bulmus;Monica Woodward;Lianne Lin;Niren Murthy

  • Annexin A1, formyl peptide receptor, and NOX1 orchestrate epithelial repair

    Giovanna Leoni;Ashfaqul Alam;Philipp Alexander Neumann;J. David Lambeth

  • Nanoparticle delivery of CRISPR into the brain rescues a mouse model of fragile X syndrome from exaggerated repetitive behaviours

    Bumwhee Lee;Kunwoo Lee;Shree Panda;Rodrigo Gonzales-Rojas

  • Design and synthesis of pH-responsive polymeric carriers that target uptake and enhance the intracellular delivery of oligonucleotides.

    Niren Murthy;Jean Campbell;Nelson Fausto;Allan S. Hoffman

Frequent Co-Authors

Patrick S. Stayton
Patrick S. Stayton University of Washington
Michael Davis
Michael Davis Georgia Institute of Technology
Allan S. Hoffman
Allan S. Hoffman University of Washington
Lee W. Riley
Lee W. Riley University of California, Berkeley
Oliver W. Press
Oliver W. Press University of Washington
Bali Pulendran
Bali Pulendran Stanford University
Lawrence A. Crum
Lawrence A. Crum University of Washington
Andrés J. García
Andrés J. García Georgia Institute of Technology
Sergey Dikalov
Sergey Dikalov Vanderbilt University Medical Center
Volga Bulmus
Volga Bulmus Izmir Institute of Technology

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