World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
84
Citations
29920
World Ranking
3275
National Ranking
1660

Overview

Sergey Dikalov is affiliated with Vanderbilt University Medical Center in the United States. Their research primarily focuses on the intersection of medicine and biochemistry, genetics, and molecular biology, with particular attention to molecular biology and physiology within these broader fields.

The scientist's work includes extensive research on mitochondrial function and pathology, adipose tissue and metabolism, metabolism and genetic disorders, as well as diet and metabolism studies. Additional key research topics encompass eicosanoids and hypertension pharmacology, esophageal cancer research and treatment, and the roles of nitric oxide and endothelin effects.

They have published numerous papers in several prominent venues, including:

  • Hypertension
  • Free Radical Biology and Medicine
  • Gastroenterology
  • Circulation Research
  • International Journal of Molecular Sciences

Frequent collaborators in their research include Anna Dikalova, Mingfang Ao, Alexander Panov, Vladimir Mayorov, and Liliya Tkachuk. These collaborations have contributed to a substantial body of work spanning multiple publications.

Among their recent publications are:

  • Cardiolipin, Perhydroxyl Radicals, and Lipid Peroxidation in Mitochondrial Dysfunctions and Aging, 2020, Oxidative Medicine and Cellular Longevity
  • Optimizing an Antioxidant TEMPO Copolymer for Reactive Oxygen Species Scavenging and Anti-Inflammatory Effects in Vivo, 2021, Bioconjugate Chemistry
  • Metabolic Syndrome and β-Oxidation of Long-Chain Fatty Acids in the Brain, Heart, and Kidney Mitochondria, 2022, International Journal of Molecular Sciences
  • Breast cancer chemotherapy induces vascular dysfunction and hypertension through a NOX4-dependent mechanism, 2022, Journal of Clinical Investigation
  • Mitochondrial Isolevuglandins Contribute to Vascular Oxidative Stress and Mitochondria-Targeted Scavenger of Isolevuglandins Reduces Mitochondrial Dysfunction and Hypertension, 2020, Hypertension

Best Publications

  • Role of the T cell in the genesis of angiotensin II–induced hypertension and vascular dysfunction

    Tomasz J. Guzik;Nyssa E. Hoch;Kathryn A. Brown;Louise A. McCann

  • Oxidation of tetrahydrobiopterin leads to uncoupling of endothelial cell nitric oxide synthase in hypertension

    Ulf Landmesser;Sergey Dikalov;S. Russ Price;Louise McCann

  • NAD(P)H Oxidase 4 Mediates Transforming Growth Factor-β1-Induced Differentiation of Cardiac Fibroblasts Into Myofibroblasts

    Ioan Cucoranu;Roza Clempus;Anna Dikalova;Patrick J. Phelan

  • Cross talk between mitochondria and NADPH oxidases

    Sergey Dikalov

  • Interactions of peroxynitrite, tetrahydrobiopterin, ascorbic acid, and thiols: implications for uncoupling endothelial nitric-oxide synthase.

    Nermin Kuzkaya;Norbert Weissmann;David G. Harrison;Sergey Dikalov

  • Molecular Mechanisms of Angiotensin II–Mediated Mitochondrial Dysfunction Linking Mitochondrial Oxidative Damage and Vascular Endothelial Dysfunction

    Abdulrahman K. Doughan;David G. Harrison;Sergey I. Dikalov

  • Therapeutic Targeting of Mitochondrial Superoxide in Hypertension

    Anna E. Dikalova;Alfiya T. Bikineyeva;Klaudia Budzyn;Rafal R. Nazarewicz

  • Vascular Oxidative Stress and Endothelial Dysfunction in Patients With Chronic Heart Failure Role of Xanthine-Oxidase and Extracellular Superoxide Dismutase

    Ulf Landmesser;Stephan Spiekermann;Sergey Dikalov;Helma Tatge

  • ROLE OF P47(PHOX) IN VASCULAR OXIDATIVE STRESS AND HYPERTENSION CAUSED BY ANGIOTENSIN II

    Ulf Landmesser;Hua Cai;Sergey Dikalov;Louise McCann

  • Measurement of Reactive Oxygen Species in Cardiovascular Studies

    Sergey Dikalov;Kathy K. Griendling;David G. Harrison

  • Methods for detection of mitochondrial and cellular reactive oxygen species.

    Sergey I. Dikalov;David G. Harrison

  • Novel Role of gp91phox-Containing NAD(P)H Oxidase in Vascular Endothelial Growth Factor–Induced Signaling and Angiogenesis

    Masuko Ushio-Fukai;Yan Tang;Tohru Fukai;Sergey I. Dikalov

  • Role of xanthine oxidoreductase and NAD(P)H oxidase in endothelial superoxide production in response to oscillatory shear stress.

    J. Scott McNally;Michael E. Davis;Don P. Giddens;Aniket Saha

  • Bone Morphogenic Protein 4 Produced in Endothelial Cells by Oscillatory Shear Stress Induces Monocyte Adhesion by Stimulating Reactive Oxygen Species Production From a Nox1-Based NADPH Oxidase

    George P. Sorescu;Hannah Song;Sarah L. Tressel;Jinah Hwang

  • DC isoketal-modified proteins activate T cells and promote hypertension

    Annet Kirabo;Vanessa Fontana;Ana P C de Faria;Roxana Loperena

  • NOX1 OVEREXPRESSION POTENTIATES ANGIOTENSIN II-INDUCED HYPERTENSION AND VASCULAR SMOOTH MUSCLE HYPERTROPHY IN TRANSGENIC MICE

    Anna Dikalova;Roza Clempus;Bernard Lassègue;Guangjie Cheng

  • Atrial fibrillation increases production of superoxide by the left atrium and left atrial appendage: role of the NADPH and xanthine oxidases

    Samuel C. Dudley;Nyssa E. Hoch;Louise A. McCann;Clegg Honeycutt

  • Distinct roles of Nox1 and Nox4 in basal and angiotensin II-stimulated superoxide and hydrogen peroxide production.

    Sergey I. Dikalov;Anna E. Dikalova;Alfiya T. Bikineyeva;Harald H.H.W. Schmidt

  • Role of xanthine oxidoreductase and NAD(P)H oxidase in endothelial superoxide production in response to oscillatory shear stress : Vascular signaling by free radicals

    J. Scott Mcnally;Michael E. Davis;Don P. Giddens;Aniket Saha

  • Abstract 1229: Molecular Mechanisms of Angiotensin II-Mediated Mitochondrial Dysfunction: Linking Mitochondrial Oxidative Damage and Vascular Endothelial Dysfunction

    Abdulrahman Doughan;David Harrison;Sergey Dikalov

Frequent Co-Authors

David G. Harrison
David G. Harrison Vanderbilt University
Kathy K. Griendling
Kathy K. Griendling Emory University
Samuel C. Dudley
Samuel C. Dudley University of Minnesota
Tohru Fukai
Tohru Fukai Veterans Health Administration
Michael Davis
Michael Davis Georgia Institute of Technology
Hanjoong Jo
Hanjoong Jo Emory University
L. Jackson Roberts
L. Jackson Roberts Vanderbilt University
Niren Murthy
Niren Murthy University of California, Berkeley
Ronald P. Mason
Ronald P. Mason National Institutes of Health
Tomasz J. Guzik
Tomasz J. Guzik University of Glasgow

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