World's Best Scientists 2026 revealed!

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Biology and Biochemistry

D-Index
95
Citations
30356
World Ranking
1920
National Ranking
128

Medicine

D-Index
98
Citations
31368
World Ranking
8994
National Ranking
504

Overview

Ralf P. Brandes is affiliated with Goethe University Frankfurt in Germany. Their research spans extensive work in biochemistry, genetics, molecular biology, and medicine, with particular focus on molecular biology, cancer research, physiology, immunology, and biochemistry.

The scientist's main research topics encompass:

  • Cancer-related molecular mechanisms research
  • RNA modifications and cancer
  • RNA research and splicing
  • Nitric oxide and endothelin effects
  • RNA and protein synthesis mechanisms
  • Eicosanoids and hypertension pharmacology
  • Neutrophil, myeloperoxidase, and oxidative mechanisms

Ralf P. Brandes has published in several prominent scientific venues, including:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Circulation Research
  • Nature Communications
  • Redox Biology
  • European Heart Journal

Among their recent papers are:

  • "Mapping the Endothelial Cell S-Sulfhydrome Highlights the Crucial Role of Integrin Sulfhydration in Vascular Function," 2020, Circulation
  • "Aging-regulated anti-apoptotic long non-coding RNA Sarrah augments recovery from acute myocardial infarction," 2020, Nature Communications
  • "Aging impairs the neurovascular interface in the heart," 2023, Science
  • "Long non-coding RNAs: novel regulators of cellular physiology and function," 2021, Pflügers Archiv - European Journal of Physiology
  • "Glucose-Stimulated Insulin Secretion Fundamentally Requires H2O2 Signaling by NADPH Oxidase 4," 2020, Diabetes

The scientist collaborates frequently with other researchers, including:

  • Matthias S. Leisegang
  • Timothy Warwick
  • Ilka Wittig
  • Stefan Günther
  • James A. Oo

Best Publications

  • Transdifferentiation of Blood-Derived Human Adult Endothelial Progenitor Cells Into Functionally Active Cardiomyocytes

    Cornel Badorff;Ralf P. Brandes;Rüdiger Popp;Stefan Rupp

  • Apocynin Is Not an Inhibitor of Vascular NADPH Oxidases but an Antioxidant

    Sabine Heumüller;Sven Wind;Eduardo Barbosa-Sicard;Harald H.H.W. Schmidt

  • A gp91phox Containing NADPH Oxidase Selectively Expressed in Endothelial Cells Is a Major Source of Oxygen Radical Generation in the Arterial Wall

    A. Görlach;R. P. Brandes;K. Nguyen;M. Amidi

  • Nox family NADPH oxidases: Molecular mechanisms of activation

    Ralf P. Brandes;Norbert Weissmann;Katrin Schröder

  • Nox4 Is a Protective Reactive Oxygen Species Generating Vascular NADPH Oxidase

    Katrin Schröder;Min Zhang;Sebastian Benkhoff;Anja Mieth

  • Direct Interaction of the Novel Nox Proteins with p22phox Is Required for the Formation of a Functionally Active NADPH Oxidase

    Rashmi K. Ambasta;Pravir Kumar;Kathy K. Griendling;Harald H.H.W. Schmidt

  • The E-loop is involved in hydrogen peroxide formation by the NADPH oxidase Nox4.

    Ina Takac;Katrin Schröder;Leilei Zhang;Bernard Lardy

  • Endothelium-Derived Hyperpolarizing Factor Synthase (Cytochrome P450 2C9) Is a Functionally Significant Source of Reactive Oxygen Species in Coronary Arteries

    Ingrid Fleming;U. Ruth Michaelis;Daniel Bredenkötter;Beate Fisslthaler

  • Thrombin activates the hypoxia-inducible factor-1 signaling pathway in vascular smooth muscle cells: Role of the p22(phox)-containing NADPH oxidase.

    A. Görlach;I. Diebold;V. B. Schini-Kerth;U. Berchner-Pfannschmidt

  • Vascular NADPH oxidases: molecular mechanisms of activation

    Ralf P. Brandes;Jörg Kreuzer

  • NADPH oxidase-4 mediates protection against chronic load-induced stress in mouse hearts by enhancing angiogenesis

    Min Zhang;Alison Brewer;Katrin Schröder;Celio Santos Xavier Da Costa Dos Santos

  • NADPH Oxidase Plays a Central Role in Blood-Brain Barrier Damage in Experimental Stroke

    Timo Kahles;Peter Luedike;Matthias Endres;Hans-Joachim Galla

  • AT1 Receptor Agonistic Antibodies From Preeclamptic Patients Stimulate NADPH Oxidase

    Ralf Dechend;Christiane Viedt;Dominik N. Müller;Bernhard Ugele

  • Antioxidative stress–associated genes in circulating progenitor cells: evidence for enhanced resistance against oxidative stress

    Elisabeth Dernbach;Carmen Urbich;Ralf P. Brandes;Wolf K. Hofmann

  • MicroRNA-29 in Aortic Dilation: Implications for Aneurysm Formation

    Reinier A. Boon;Timon Seeger;Susanne Heydt;Ariane Fischer

  • Acetylation-dependent regulation of endothelial Notch signalling by the SIRT1 deacetylase

    Virginia Guarani;Gianluca Deflorian;Claudio A Franco;Marcus Kruger

  • An endothelium-derived hyperpolarizing factor distinct from NO and prostacyclin is a major endothelium-dependent vasodilator in resistance vessels of wild-type and endothelial NO synthase knockout mice

    Ralf P. Brandes;Friedrich-Hubertus Schmitz-Winnenthal;Michel Félétou;Axel Gödecke

  • Cell-to-Cell Connection of Endothelial Progenitor Cells With Cardiac Myocytes by Nanotubes: A Novel Mechanism for Cell Fate Changes?

    Masamichi Koyanagi;Ralf P. Brandes;Judith Haendeler;Andreas M. Zeiher

  • Apocynin Is Not an Inhibitor of Vascular NADPH Oxidases but an Antioxidant. Commentary

    Rhian M. Touyz;Sabine Heumüller;Sven Wind;Eduardo Barbosa-Sicard

  • MicroRNA-29 in Aortic Dilation: Implications for Aneurysm Formation Short Communication

    Reinier A. Boon;Timon Seeger;Susanne Heydt;Ariane Fischer

Frequent Co-Authors

Rudi Busse
Rudi Busse Goethe University Frankfurt
Norbert Weissmann
Norbert Weissmann University of Giessen
Ingrid Fleming
Ingrid Fleming Goethe University Frankfurt
Ajay M. Shah
Ajay M. Shah King's College London
Stefanie Dimmeler
Stefanie Dimmeler Goethe University Frankfurt
Ralph T. Schermuly
Ralph T. Schermuly University of Giessen
Ilka Wittig
Ilka Wittig Goethe University Frankfurt
Werner Seeger
Werner Seeger University of Giessen
Andreas M. Zeiher
Andreas M. Zeiher Goethe University Frankfurt
Gerd Geisslinger
Gerd Geisslinger Goethe University Frankfurt

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