World's Best Scientists 2026 revealed!

D-Index & Metrics

Medicine

D-Index
102
Citations
38758
World Ranking
7657
National Ranking
435

Overview

Gerd Geisslinger is affiliated with Goethe University Frankfurt in Germany. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with 176 and 93 publications respectively. Within these areas, key subfields include Molecular Biology, Physiology, Pharmacology, Immunology, and Rheumatology.

The scientist's work covers a range of topics, notably Pain Mechanisms and Treatments, Sphingolipid Metabolism and Signaling, Eicosanoids and Hypertension Pharmacology, Metabolomics and Mass Spectrometry Studies, SARS-CoV-2 and COVID-19 Research, Pharmacological Effects of Natural Compounds, and Inflammatory mediators and NSAID effects.

Publications by Geisslinger have appeared frequently in several scientific venues. The top publication venues include:

  • International Journal of Molecular Sciences
  • Cells
  • Scientific Reports
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Research Square (Research Square)

Notable recent papers highlight diverse areas of research and include:

  • The blood-brain barrier is dysregulated in COVID-19 and serves as a CNS entry route for SARS-CoV-2 (2022, Stem Cell Reports)
  • Formation, Signaling and Occurrence of Specialized Pro-Resolving Lipid Mediators-What is the Evidence so far? (2022, Frontiers in Pharmacology)
  • Identification of Inhibitors of SARS-CoV-2 3CL-Pro Enzymatic Activity Using a Small Molecule in Vitro Repurposing Screen (2021, ACS Pharmacology & Translational Science)
  • Autophagy activation, lipotoxicity and lysosomal membrane permeabilization synergize to promote pimozide- and loperamide-induced glioma cell death (2021, Autophagy)
  • A SARS-CoV-2 cytopathicity dataset generated by high-content screening of a large drug repurposing collection (2021, Scientific Data)

Throughout their career, Geisslinger has collaborated often with several researchers including Robert Gurke, Lisa Hahnefeld, Dominique Thomas, Marco Sisignano, and Sandra Trautmann, with collaboration counts ranging from 20 to 43 publications each.

Best Publications

  • Cyclooxygenase-independent actions of cyclooxygenase inhibitors

    Irmgard Tegeder;Josef Pfeilschifter;Gerd Geisslinger

  • COX-2 independent induction of cell cycle arrest and apoptosis in colon cancer cells by the selective COX-2 inhibitor celecoxib

    Sabine Grösch;Irmgard Tegeder;Ellen Niederberger;Lutz Bräutigam

  • GTP cyclohydrolase and tetrahydrobiopterin regulate pain sensitivity and persistence

    Irmgard Tegeder;Michael Costigan;Robert S Griffin;Andrea Abele

  • Cyclooxygenase-2 (COX-2)–Independent Anticarcinogenic Effects of Selective COX-2 Inhibitors

    Sabine Grösch;Thorsten Jürgen Maier;Susanne Schiffmann;Gerd Geisslinger

  • Chain length-specific properties of ceramides.

    Sabine Grösch;Susanne Schiffmann;Gerd Geisslinger

  • Up-regulation of cyclooxygenase-2 mRNA in the rat spinal cord following peripheral inflammation

    Flora Beiche;Stefan Scheuerer;Kay Brune;Gerd Geisslinger

  • Ziconotide for treatment of severe chronic pain

    Achim Schmidtko;Jörn Lötsch;Rainer Freynhagen;Gerd Geisslinger

  • COX-dependent mechanisms involved in the antinociceptive action of NSAIDs at central and peripheral sites.

    Maria Burian;Gerd Geisslinger

  • Pharmacokinetics of opioids in liver disease.

    Irmgard Tegeder;Jörn Lötsch;Gerd Geisslinger

  • Microarray analysis of altered sphingolipid metabolism reveals prognostic significance of sphingosine kinase 1 in breast cancer

    Eugen Ruckhäberle;Achim Rody;Knut Engels;Regine Gaetje

  • Genetic predictors of the clinical response to opioid analgesics: Clinical utility and future perspectives

    Jörn Lötsch;Carsten Skarke;Jürgen Liefhold;Gerd Geisslinger

  • Mechanism-based treatment for chemotherapy-induced peripheral neuropathic pain

    Marco Sisignano;Ralf Baron;Klaus Scholich;Gerd Geisslinger

  • Ceramide synthases and ceramide levels are increased in breast cancer tissue

    Susanne Schiffmann;Jessica Sandner;Kerstin Birod;Ivonne Wobst

  • Capturing adenylyl cyclases as potential drug targets.

    Sandra Pierre;Thomas Eschenhagen;Gerd Geisslinger;Klaus Scholich

  • Opioids As Modulators of Cell Death and Survival—Unraveling Mechanisms and Revealing New Indications

    Irmgard Tegeder;Gerd Geisslinger

  • Analgesic effects of morphine and morphine-6-glucuronide in a transcutaneous electrical pain model in healthy volunteers

    Carsten Skarke;Jutta Darimont;Helmut Schmidt;Gerd Geisslinger

  • The IKK-NF-κB pathway: a source for novel molecular drug targets in pain therapy?

    Ellen Niederberger;Gerd Geisslinger

  • Cyclooxygenase-2 (COX-2)-dependent and -independent anticarcinogenic effects of celecoxib in human colon carcinoma cells.

    Thorsten Jürgen Maier;Karin Schilling;Ronald Schmidt;Gerd Geisslinger

  • Incidence and costs of adverse drug reactions during hospitalisation: computerised monitoring versus stimulated spontaneous reporting.

    Harald Dormann;Uta Muth-Selbach;Sabine Krebs;Manfred Criegee-Rieck

  • No NO, no pain? The role of nitric oxide and cGMP in spinal pain processing.

    Achim Schmidtko;Irmgard Tegeder;Gerd Geisslinger

Frequent Co-Authors

Jörn Lötsch
Jörn Lötsch Goethe University Frankfurt
Kay Brune
Kay Brune University of Erlangen-Nuremberg
Gerd Kobal
Gerd Kobal University of Erlangen-Nuremberg
Alfred Ultsch
Alfred Ultsch Philipp University of Marburg
Clifford J. Woolf
Clifford J. Woolf Boston Children's Hospital
Stefan Zeuzem
Stefan Zeuzem Goethe University Frankfurt
Ralf P. Brandes
Ralf P. Brandes Goethe University Frankfurt
Thomas Hummel
Thomas Hummel TU Dresden
Ingrid Fleming
Ingrid Fleming Goethe University Frankfurt
Domenico Del Turco
Domenico Del Turco Goethe University Frankfurt

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Pursuing a career in medicine involves more than just earning a medical degree. Many students explore related health fields and advanced qualifications that can open doors to new opportunities. Allied degrees such as an online master of health administration help future professionals develop strong leadership and management skills in the healthcare sector.

Affordability is often a top concern for students. There are options for cheapest mha programs that offer quality education without a hefty price tag. For those who wish to advance their clinical expertise, flexible and accredited dnp online programs cheap are also accessible, leading to roles in advanced practice nursing and healthcare leadership.

Pharmacists play a vital role in healthcare delivery. If pharmaceutical studies interest you, consider an online pharmd program for a career in pharmacy with the convenience of distance learning. Each pathway offers diverse options for growth and advancement in the healthcare industry.

Best Scientists Citing Gerd Geisslinger

Trending Scientists