World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
53
Citations
9224
World Ranking
16251
National Ranking
23

Research.com Recognitions

  • 2019 - Prize of the Foundation for Polish Science - Nagroda Fundacji na rzecz Nauki Polskiej for developing a new technological platform for obtaining biologically active compounds, in particular proteolytic enzymes inhibitors

Overview

Marcin Drag is affiliated with Wrocław University of Science and Technology in Poland. Their research primarily focuses on the fields of Biochemistry, Genetics and Molecular Biology, and Medicine, with significant contributions in subfields such as Molecular Biology, Infectious Diseases, Oncology, Immunology, and Computational Theory and Mathematics.

The scientist's work addresses several main topics including peptidase inhibition and analysis, SARS-CoV-2 and COVID-19 research, computational drug discovery methods, ubiquitin and proteasome pathways, advanced biosensing and bioanalysis techniques, RNA interference and gene delivery, and click chemistry applications.

Recent notable publications include:

  • Activity profiling and crystal structures of inhibitor-bound SARS-CoV-2 papain-like protease: A framework for anti-COVID-19 drug design (2020, Science Advances)
  • SARS-CoV-2 Mpro inhibitors and activity-based probes for patient-sample imaging (2020, Nature Chemical Biology)
  • The Strategies to Support the COVID-19 Vaccination with Evidence-Based Communication and Tackling Misinformation (2021, Vaccines)
  • Mechanistic insights into COVID-19 by global analysis of the SARS-CoV-2 3CLpro substrate degradome (2021, Cell Reports)
  • Targeting SARS-CoV-2 Proteases for COVID-19 Antiviral Development (2022, Frontiers in Chemistry)

Marcin Drag frequently collaborates with researchers such as Wioletta Rut, Mikołaj Żmudziński, Marcin Poręba, Katarzyna Groborz, and Paulina Kasperkiewicz.

Their publications are often found in venues including bioRxiv (Cold Spring Harbor Laboratory), Research Square (Research Square), Journal of Medicinal Chemistry, Biochemical Journal, and Protein Science.

In 2019, Marcin Drag received the Prize of the Foundation for Polish Science (Nagroda Fundacji na rzecz Nauki Polskiej) for developing a new technological platform for obtaining biologically active compounds, particularly proteolytic enzyme inhibitors.

Best Publications

  • Emerging principles in protease-based drug discovery

    Marcin Drag;Guy S. Salvesen

  • Activity profiling and crystal structures of inhibitor-bound SARS-CoV-2 papain-like protease: A framework for anti-COVID-19 drug design.

    Wioletta Rut;Zongyang Lv;Zongyang Lv;Mikolaj Zmudzinski;Stephanie Patchett

  • SARS-CoV-2 M pro inhibitors and activity-based probes for patient-sample imaging

    Wioletta Rut;Katarzyna Groborz;Linlin Zhang;Xinyuanyuan Sun

  • FLIPL induces caspase 8 activity in the absence of interdomain caspase 8 cleavage and alters substrate specificity

    Cristina Pop;Andrew Oberst;Marcin Drag;Marcin Drag;Bram J. Van Raam

  • Caspase Substrates and Inhibitors

    Marcin Poręba;Aleksandra Stróżyk;Guy S. Salvesen;Marcin Drąg

  • A constitutively active and uninhibitable caspase-3 zymogen efficiently induces apoptosis.

    Jad Walters;Cristina Pop;Fiona L. Scott;Marcin Drag

  • SUMO-mediated regulation of NLRP3 modulates inflammasome activity.

    Rachael Barry;Rachael Barry;Sidonie Wicky John;Gianmaria Liccardi;Tencho Tenev

  • Small ubiquitin-related modifier (SUMO)-specific proteases: profiling the specificities and activities of human SENPs.

    Jowita Mikolajczyk;Marcin Drag;Marcin Drag;Miklós Békés;Miklós Békés;John T. Cao

  • Design of ultrasensitive probes for human neutrophil elastase through hybrid combinatorial substrate library profiling.

    Paulina Kasperkiewicz;Marcin Poreba;Scott J. Snipas;Heather Parker

  • Plasmodium falciparum neutral aminopeptidases: new targets for anti-malarials

    Tina S Skinner-Adams;Colin M Stack;Katharine R Trenholme;Christopher L Brown;Christopher L Brown

  • Metallo-aminopeptidase inhibitors

    Artur Mucha;Marcin Drag;John P. Dalton;Paweł Kafarski

  • DeSUMOylating enzymes—SENPs

    Marcin Drag;Marcin Drag;Guy S. Salvesen

  • Distribution and paralogue specificity of mammalian deSUMOylating enzymes.

    Nagamalleswari Kolli;Jowita Mikolajczyk;Marcin Drag;Debaditya Mukhopadhyay

  • Esters of betulin and betulinic acid with amino acids have improved water solubility and are selectively cytotoxic toward cancer cells.

    Malgorzata Drag-Zalesinska;Julita Kulbacka;Jolanta Saczko;Teresa Wysocka

  • The Strategies to Support the COVID-19 Vaccination with Evidence-Based Communication and Tackling Misinformation.

    Piotr Rzymski;Leszek Borkowski;Marcin Drąg;Robert Flisiak

  • Probing the S1 specificity pocket of the aminopeptidases that generate antigenic peptides.

    Efthalia Zervoudi;Athanasios Papakyriakou;Dimitra Georgiadou;Irini Evnouchidou

  • Aminopeptidase Fingerprints, an Integrated Approach for Identification of Good Substrates and Optimal Inhibitors

    Marcin Drag;Marcin Drag;Matthew Bogyo;Jonathan A. Ellman;Guy S. Salvesen

  • Comparision of the cytotoxic effects of birch bark extract, betulin and betulinic acid towards human gastric carcinoma and pancreatic carcinoma drug-sensitive and drug-resistant cell lines

    Marcin Drag;Pawel Surowiak;Malgorzata Drag-Zalesinska;Manfred Dietel

  • Activity profiling and structures of inhibitor-bound SARS-CoV-2-PLpro protease provides a framework for anti-COVID-19 drug design.

    Wioletta Rut;Zongyang Lv;Zongyang Lv;Mikolaj Zmudzinski;Stephanie Patchett

  • Toolbox of Fluorescent Probes for Parallel Imaging Reveals Uneven Location of Serine Proteases in Neutrophils

    Paulina Kasperkiewicz;Yoav Altman;Maximiliano D’Angelo;Guy S. Salvesen

Frequent Co-Authors

Guy S. Salvesen
Guy S. Salvesen Sanford Burnham Prebys Medical Discovery Institute
Paweł Kafarski
Paweł Kafarski Wrocław University of Science and Technology
Boris Turk
Boris Turk Jožef Stefan Institute
Matthew Bogyo
Matthew Bogyo Stanford University
John P. Dalton
John P. Dalton University of Galway
Dušan Turk
Dušan Turk Jožef Stefan Institute
Rolf Hilgenfeld
Rolf Hilgenfeld University of Lübeck
Jan Potempa
Jan Potempa University of Louisville
James C. Whisstock
James C. Whisstock Monash University
Nigel W. Bunnett
Nigel W. Bunnett New York University

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Advancing your education in biology and biochemistry opens diverse career pathways—many of which you can now pursue online. For those interested in leadership roles within healthcare, an phd in healthcare management online can prepare you for high-level administrative or policy positions.

If direct patient care is appealing, you might consider a online pharm d programs degree as a gateway into pharmacy, pharmaceutical research, or clinical consultancy. Some students seek flexibility or want to accelerate their learning; in this case, exploring dnp program no clinical options can help you earn a Doctor of Nursing Practice without extensive on-site clinical requirements.

For those drawn to human performance or rehabilitation science, an online exercise physiology degree offers further specialization. Whichever path you choose, online degrees provide the flexibility and breadth to tailor your education toward fields like research, clinical roles, healthcare management, or sports science.

Best Scientists Citing Marcin Drag

Trending Scientists

Recently Published Articles