Margot Thome

Overview

Best Publications

• Inhibition of death receptor signals by cellular FLIP

  Martin Irmler;Margot Thome;Michael Hahne;Pascal Schneider

  3429
  Citations

• Fas triggers an alternative, caspase-8-independent cell death pathway using the kinase RIP as effector molecule.

  Nils Holler;Rossana Zaru;Olivier Micheau;Margot Thome

  2295
  Citations

• Viral FLICE-inhibitory proteins (FLIPs) prevent apoptosis induced by death receptors

  Margot Thome;Pascal Schneider;Kay Hofmann;Helmut Fickenscher

  1691
  Citations

• TRAIL Receptors 1 (DR4) and 2 (DR5) Signal FADD-Dependent Apoptosis and Activate NF-κB

  Pascal Schneider;Margot Thome;Kim Burns;Jean-Luc Bodmer

  901
  Citations

• Inhibition of Fas death signals by FLIPs

  Jürg Tschopp;Martin Irmler;Margot Thome

  763
  Citations

• The caspase-8 inhibitor FLIP promotes activation of NF-κB and Erk signaling pathways

  T. Kataoka;R.C. Budd;R.C. Budd;N. Holler;M. Thome

  729
  Citations

• The Long Form of FLIP Is an Activator of Caspase-8 at the Fas Death-inducing Signaling Complex

  Olivier Micheau;Margot Thome;Pascal Schneider;Nils Holler

  647
  Citations

• Regulation of lymphocyte proliferation and death by FLIP.

  Margot Thome;Jürg Tschopp

  563
  Citations

• CARMA1, BCL-10 and MALT1 in lymphocyte development and activation.

  Margot Thome

  545
  Citations

• Association of mutations in the NALP3/CIAS1/PYPAF1 gene with a broad phenotype including recurrent fever, cold sensitivity, sensorineural deafness, and AA amyloidosis.

  Ebun Aganna;Fabio Martinon;Philip N. Hawkins;John B. Ross

  496
  Citations

• CHARACTERIZATION OF TWO RECEPTORS FOR TRAIL

  Pascal Schneider;Jean-Luc Bodmer;Margot Thome;Kay Hofmann

  457
  Citations

• Identification of CARDIAK, a RIP-like kinase that associates with caspase-1

  Margot Thome;Kay Hofmann;Kim Burns;Fabio Martinon

  451
  Citations

• TRAMP, a Novel Apoptosis-Mediating Receptor with Sequence Homology to Tumor Necrosis Factor Receptor 1 and Fas(Apo-1/CD95)

  Jean-Luc Bodmer;Kim Burns;Pascal Schneider;Kay Hofmann

  447
  Citations

• CARMA1 is a critical lipid raft- associated regulator of TCR-induced NF-κB activation

  Olivier Gaide;Benoît Favier;Daniel F. Legler;David Bonnet

  431
  Citations

• FLIP Prevents Apoptosis Induced by Death Receptors But Not by Perforin/Granzyme B, Chemotherapeutic Drugs, and Gamma Irradiation

  Takao Kataoka;Michael Schröter;Michael Hahne;Pascal Schneider

  341
  Citations

• The proteolytic activity of the paracaspase MALT1 is key in T cell activation.

  Fabien Rebeaud;Stephan Hailfinger;Anita Posevitz-Fejfar;Myriam Tapernoux

  339
  Citations

• Activating mutations in genes related to TCR signaling in angioimmunoblastic and other follicular helper T-cell-derived lymphomas

  David Vallois;Maria Pamela D. Dobay;Ryan D. Morin;Ryan D. Morin;François Lemonnier

  325
  Citations

• Requirement for CARMA1 in Antigen Receptor-Induced NF-κB Activation and Lymphocyte Proliferation

  Takeshi Egawa;Björn Albrecht;Benoît Favier;Mary Jean Sunshine

  318
  Citations

• Malt1-dependent RelB cleavage promotes canonical NF-κB activation in lymphocytes and lymphoma cell lines

  Stephan Hailfinger;Hendrik Nogai;Christiane Pelzer;Maike Jaworski

  311
  Citations

• Antigen Receptor Signaling to NF-κB via CARMA1, BCL10, and MALT1

  Margot Thome;Jean Enno Charton;Christiane Pelzer;Stephan Hailfinger

  302
  Citations