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D-Index & Metrics

Biology and Biochemistry

D-Index
58
Citations
21554
World Ranking
12913
National Ranking
484

Overview

Michael Hahne is affiliated with the Centre national de la recherche scientifique (CNRS) in France. Their research spans several areas in medicine and biochemistry, genetics, and molecular biology, with a strong focus on oncology and immunology.

Their recent scholarly work includes publications in notable journals and covers topics related to cancer biology, immune responses, and molecular mechanisms. Selected recent papers include:

  • The Role of Cancer-Associated Fibroblasts in Cancer Invasion and Metastasis, 2021, Cancers
  • Cyclin A2 maintains colon homeostasis and is a prognostic factor in colorectal cancer, 2020, Journal of Clinical Investigation
  • An intestinal TH17 cell-derived subset can initiate cancer, 2024, Nature Immunology
  • Loss of primary cilia promotes inflammation and carcinogenesis, 2022, EMBO Reports
  • APRIL-producing eosinophils are involved in gastric MALT lymphomagenesis induced by Helicobacter sp infection, 2020, Scientific Reports

Their collaboration network includes frequent co-authors such as Rossano Lattanzio, Bénédicte Lemmers, Conception Paul, Ciro Longobardi, and Valérie Pinet, reflecting ongoing research partnerships.

Michael Hahne has contributed multiple articles to publication venues such as bioRxiv (Cold Spring Harbor Laboratory), Nature Communications, Cancers, Nature Immunology, and the Journal of Clinical Investigation.

Their primary fields of study encompass Medicine and Biochemistry, Genetics, and Molecular Biology, with subfields including Molecular Biology, Oncology, Immunology, Surgery, and Cancer Research.

Their main research topics are focused on:

  • Cancer Cells and Metastasis
  • Pancreatic and Hepatic Oncology Research
  • IL-33, ST2, and ILC Pathways
  • Cancer Immunotherapy and Biomarkers
  • Heat shock proteins research
  • Immunotherapy and Immune Responses
  • T-cell and B-cell Immunology

Best Publications

  • Inhibition of death receptor signals by cellular FLIP

    Martin Irmler;Margot Thome;Michael Hahne;Pascal Schneider

  • Melanoma Cell Expression of Fas(Apo-1/CD95) Ligand: Implications for Tumor Immune Escape

    M. Hahne;D. Rimoldi;M. Schröter;P. Romero

  • Cytolytic T-cell cytotoxicity is mediated through perforin and Fas lytic pathways

    Bente Lowin;Michael Hahne;Chantal Mattmann;Jürg Tschopp

  • Conversion of Membrane-bound Fas(CD95) Ligand to Its Soluble Form Is Associated with Downregulation of Its Proapoptotic Activity and Loss of Liver Toxicity

    Pascal Schneider;Nils Holler;Jean Luc Bodmer;Michael Hahne

  • APRIL, a New Ligand of the Tumor Necrosis Factor Family, Stimulates Tumor Cell Growth

    Michael Hahne;Takao Kataoka;Michael Schröter;Kay Hofmann

  • The caspase-8 inhibitor FLIP promotes activation of NF-κB and Erk signaling pathways

    T. Kataoka;R.C. Budd;R.C. Budd;N. Holler;M. Thome

  • CD95 ligand (Fas-L/APO-1L) and tumor necrosis factor-related apoptosis-inducing ligand mediate ischemia-induced apoptosis in neurons.

    Ana Martin-Villalba;Ingrid Herr;Irmela Jeremias;Michael Hahne

  • Fas ligand expression by astrocytoma in vivo: maintaining immune privilege in the brain?

    P Saas;P R Walker;M Hahne;A L Quiquerez

  • TRAMP, a Novel Apoptosis-Mediating Receptor with Sequence Homology to Tumor Necrosis Factor Receptor 1 and Fas(Apo-1/CD95)

    Jean-Luc Bodmer;Kim Burns;Pascal Schneider;Kay Hofmann

  • Blockade of the granzyme B/perforin pathway through overexpression of the serine protease inhibitor PI-9/SPI-6 constitutes a mechanism for immune escape by tumors

    J. P. Medema;J. de Jong;L. T. C. Peltenburg;E. M. E. Verdegaal

  • Activation of Fas by FasL induces apoptosis by a mechanism that cannot be blocked by Bcl-2 or Bcl-xL

    David C. S. Huang;Michael Hahne;Michael Schroeter;Karl Frei

  • APRIL modulates B and T cell immunity.

    Jens V. Stein;Marta López-Fraga;Fernando A. Elustondo;Carla E. Carvalho-Pinto

  • FLIP Prevents Apoptosis Induced by Death Receptors But Not by Perforin/Granzyme B, Chemotherapeutic Drugs, and Gamma Irradiation

    Takao Kataoka;Michael Schröter;Michael Hahne;Pascal Schneider

  • Five tumor necrosis factor-inducible cell adhesion mechanisms on the surface of mouse endothelioma cells mediate the binding of leukocytes

    Michael Hahne;Ute Jäger;Sandra Isenmann;Rupert Hallmann

  • Heparan sulfate proteoglycan binding promotes APRIL-induced tumor cell proliferation

    J Hendriks;L Planelles;J de Jong-Odding;G Hardenberg

  • Activated B cells express functional Fas ligand

    Michael Hahne;Toufic Renno;Michael Schroeter;Martin Irmler

  • Biologically active APRIL is secreted following intracellular processing in the Golgi apparatus by furin convertase

    M López‐Fraga;R Fernández;J P Albar;M Hahne

  • Therapeutic neutralization of CD95-ligand and TNF attenuates brain damage in stroke

    A Martin-Villalba;A Martin-Villalba;M Hahne;S Kleber;J Vogel

  • Tumor Necrosis Factor-related Apoptosis-inducing Ligand (TRAIL) Induces Rheumatoid Arthritis Synovial Fibroblast Proliferation through Mitogen-activated Protein Kinases and Phosphatidylinositol 3-Kinase/Akt

    Jacques Morel;Rachel Audo;Michael Hahne;Bernard Combe

  • Oncogenic Ras inhibits Fas ligand‐mediated apoptosis by downregulating the expression of Fas

    Janos Peli;Michael Schröter;Claude Rudaz;Michael Hahne

Frequent Co-Authors

Bernard Combe
Bernard Combe University of Montpellier
Jan Paul Medema
Jan Paul Medema University of Amsterdam
Jürg Tschopp
Jürg Tschopp University of Lausanne
Pascal Schneider
Pascal Schneider University of Lausanne
Lars E. French
Lars E. French Ludwig-Maximilians-Universität München
Martin Irmler
Martin Irmler University of Lausanne
Dominique Baeten
Dominique Baeten University of Amsterdam
Margot Thome
Margot Thome University of Lausanne
Jamal Tazi
Jamal Tazi University of Montpellier
Kay Hofmann
Kay Hofmann University of Cologne

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