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Microbiology

D-Index
52
Citations
9207
World Ranking
4221
National Ranking
1634

Overview

Ralph C. Budd is affiliated with the University of Vermont in the United States and has contributed to research primarily in the fields of Medicine and Immunology and Microbiology. Their work spans multiple subfields including Immunology, Infectious Diseases, Oncology, Molecular Biology, and Epidemiology.

The scientist's research focuses on areas such as COVID-19 clinical research studies, microscopic colitis, inflammatory bowel disease, long-term effects of COVID-19, SARS-CoV-2 and COVID-19 research, T-cell and B-cell immunology, and inflammasome and immune disorders.

Recent research output includes the following papers:

  • Daily, oral FMT for long-term maintenance therapy in ulcerative colitis: results of a single-center, prospective, randomized pilot study (2021) published in BMC Gastroenterology
  • Targeting mitochondrial oxidative stress with MitoQ reduces NET formation and kidney disease in lupus-prone MRL-lpr mice (2020) published in Lupus Science & Medicine
  • Efficacy of Combination Therapy with the JAK Inhibitor Baricitinib in the Treatment of COVID-19 (2022) published in SN Comprehensive Clinical Medicine
  • T Cell Homeostatic Proliferation Promotes a Redox State That Drives Metabolic and Epigenetic Upregulation of Inflammatory Pathways in Lupus (2021) published in Antioxidants and Redox Signaling
  • Efficacy of Combination Therapy With The JAK Inhibitor Baricitinib In The Treatment of COVID-19 (2021) published in Research Square (Research Square)

Frequent co-authors in their research include:

  • Karen A. Fortner
  • Cheryl Collins
  • Benjamin Littenberg
  • Jessica W. Crothers
  • Nathaniel D. Chu

Notable publication venues where their work appears most often are:

  • Research Square (Research Square)
  • BMC Gastroenterology
  • Lupus Science & Medicine
  • SN Comprehensive Clinical Medicine
  • Antioxidants and Redox Signaling

Best Publications

  • The caspase-8 inhibitor FLIP promotes activation of NF-κB and Erk signaling pathways

    T. Kataoka;R.C. Budd;R.C. Budd;N. Holler;M. Thome

  • Caspase Activation Is Required for T Cell Proliferation

    Norman J. Kennedy;Takao Kataoka;Jürg Tschopp;Ralph C. Budd;Ralph C. Budd

  • Diversity of cytokine synthesis and function of mouse CD4+ T cells.

    T. R. Mosmann;J. H. Schumacher;N. F. Street;R. Budd

  • The CD95 receptor: apoptosis revisited.

    Marcus E. Peter;Ralph C. Budd;Julie Desbarats;Stephen M. Hedrick

  • cFLIP regulation of lymphocyte activation and development

    Ralph C. Budd;Wen-Chen Yeh;Jürg Tschopp

  • Apoptosis regulators Fas and Bim cooperate in shutdown of chronic immune responses and prevention of autoimmunity.

    Peter D. Hughes;Gabrielle T. Belz;Karen A. Fortner;Ralph C. Budd

  • Developmentally regulated expression of T cell receptor beta chain variable domains in immature thymocytes.

    R C Budd;G C Miescher;R C Howe;R K Lees

  • Morphological and cytochemical determination of cell death by apoptosis

    Douglas J. Taatjes;Burton E. Sobel;Ralph C. Budd

  • Activation-induced cell death

    Ralph C Budd

  • Death receptors couple to both cell proliferation and apoptosis

    Ralph C. Budd

  • A CD3- subset of CD4-8+ thymocytes: a rapidly cycling intermediate in the generation of CD4+8+ cells.

    H R MacDonald;R C Budd;R C Howe

  • The caspase 8 inhibitor c-FLIP(L) modulates T-cell receptor-induced proliferation but not activation-induced cell death of lymphocytes.

    Susanne M. A. Lens;Takao Kataoka;Takao Kataoka;Karen A. Fortner;Antoine Tinel

  • Reactive oxygen species induce virus-independent MAVS oligomerization in systemic lupus erythematosus.

    Iwona A. Buskiewicz;Theresa Montgomery;Elizabeth C. Yasewicz;Sally A. Huber

  • JNK, but not MAPK, activation is associated with Fas-mediated apoptosis in human T cells.

    David J. Wilson;Karen A. Fortner;David H. Lynch;Raymond R. Mattingly

  • Cellular FLIP (Long Form) Regulates CD8+ T Cell Activation through Caspase-8-Dependent NF-κB Activation

    Austin Dohrman;Takao Kataoka;Solange Cuenin;Solange Cuenin;Jennifer Q. Russell

  • Redox amplification of apoptosis by caspase-dependent cleavage of glutaredoxin 1 and S-glutathionylation of Fas

    Vikas Anathy;Scott W. Aesif;Amy S. Guala;Marije Havermans

  • Apoptosis of Fashigh CD4+ Synovial T Cells by Borrelia-reactive Fas-ligandhigh γδ T Cells in Lyme Arthritis

    Michael S. Vincent;Karen Roessner;David Lynch;David Wilson

  • Inhibition of apoptosis and caspase‐3 in vascular smooth muscle cells by plasminogen activator inhibitor type‐1

    Yabing Chen;Robert J. Kelm;Ralph C. Budd;Burton E. Sobel

  • γδ T Cells Promote a Th1 Response during Coxsackievirus B3 Infection In Vivo: Role of Fas and Fas Ligand

    Sally Huber;Cuixia Shi;Ralph C. Budd

  • CD2-CD4-CD8- lymph node T lymphocytes in MRL lpr/lpr mice are derived from a CD2+CD4+CD8+ thymic precursor.

    M. M. T. Landolfi;N. Van Houten;J. Q. Russell;R. Scollay

Frequent Co-Authors

Jürg Tschopp
Jürg Tschopp University of Lausanne
Yvonne M. W. Janssen-Heininger
Yvonne M. W. Janssen-Heininger University of Vermont
Sally A. Huber
Sally A. Huber University of Vermont
Michael P. Murphy
Michael P. Murphy University of Cambridge
Albert van der Vliet
Albert van der Vliet University of Vermont
Douglas J. Taatjes
Douglas J. Taatjes University of Vermont
Burton E. Sobel
Burton E. Sobel Washington University in St. Louis
David H. Lynch
David H. Lynch ApoVax, Inc.
Andreas Strasser
Andreas Strasser Walter and Eliza Hall Institute of Medical Research
Ye-Shih Ho
Ye-Shih Ho Wayne State University

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