Martin Leverkus

Overview

Best Publications

• IAP Antagonists Target cIAP1 to Induce TNFα-Dependent Apoptosis

  James E. Vince;W. Wei-Lynn Wong;Nufail Khan;Rebecca Feltham

  1271
  Citations

• cIAPs Block Ripoptosome Formation, a RIP1/Caspase-8 Containing Intracellular Cell Death Complex Differentially Regulated by cFLIP Isoforms

  Maria Feoktistova;Maria Feoktistova;Peter Geserick;Peter Geserick;Beate Kellert;Diana Panayotova Dimitrova

  1188
  Citations

• Crystal Violet Assay for Determining Viability of Cultured Cells

  Maria Feoktistova;Peter Geserick;Martin Leverkus

  783
  Citations

• Cutaneous, gastrointestinal, hepatic, endocrine, and renal side-effects of anti-PD-1 therapy.

  Lars Hofmann;Andrea Forschner;Carmen Loquai;Simone M. Goldinger

  695
  Citations

• Neurological, respiratory, musculoskeletal, cardiac and ocular side-effects of anti-PD-1 therapy.

  Lisa Zimmer;Simone M. Goldinger;Lars Hofmann;Carmen Loquai

  577
  Citations

• Regulation of tumor necrosis factor-related apoptosis-inducing ligand sensitivity in primary and transformed human keratinocytes

  Martin Leverkus;Manfred Neumann;Thilo Mengling;Charles T. Rauch

  425
  Citations

• NFκB activation by Fas is mediated through FADD, caspase-8, and RIP and is inhibited by FLIP

  Sebastian Kreuz;Daniela Siegmund;Jost-Julian Rumpf;Dierk Samel

  315
  Citations

• Cellular IAPs inhibit a cryptic CD95-induced cell death by limiting RIP1 kinase recruitment

  Peter Geserick;Peter Geserick;Mike Hupe;Maryline Moulin;W Wei-Lynn Wong

  280
  Citations

• Fas/CD95-Induced Chemokines Can Serve as “Find-Me” Signals for Apoptotic Cells

  Sean P. Cullen;Conor M. Henry;Conor J. Kearney;Susan E. Logue

  261
  Citations

• Co-operative and Hierarchical Binding of c-FLIP and Caspase-8: A Unified Model Defines How c-FLIP Isoforms Differentially Control Cell Fate

  Michelle A. Hughes;Ian R. Powley;Rebekah Jukes-Jones;Sebastian Horn

  253
  Citations

• IgG4 and IgE are the major immunoglobulins targeting the NC16A domain of BP180 in bullous pemphigoid: Serum levels of these immunoglobulins reflect disease activity

  Rebekka Döpp;Enno Schmidt;Iakov Chimanovitch;Martin Leverkus

  233
  Citations

• Elevated serum levels of interleukin-10 in patients with metastatic malignant melanoma.

  W Dummer;J C Becker;A Schwaaf;M Leverkus

  185
  Citations

• Programmed necrosis and necroptosis signalling

  Maria Feoktistova;Martin Leverkus

  180
  Citations

• Proapoptotic signalling through Toll-like receptor-3 involves TRIF-dependent activation of caspase-8 and is under the control of inhibitor of apoptosis proteins in melanoma cells.

  A Weber;Z Kirejczyk;R Besch;S Potthoff

  173
  Citations

• Neoadjuvant Imatinib in Advanced Primary or Locally Recurrent Dermatofibrosarcoma Protuberans: A Multicenter Phase II DeCOG Trial with Long-term Follow-up

  Selma Ugurel;Thomas Mentzel;Jochen Utikal;Peter Helmbold

  160
  Citations

• Proteasome Inhibition Results in TRAIL Sensitization of Primary Keratinocytes by Removing the Resistance-Mediating Block of Effector Caspase Maturation

  Martin Leverkus;Martin R. Sprick;Tina Wachter;Thilo Mengling

  151
  Citations

• RIPK1 Suppresses a TRAF2-Dependent Pathway to Liver Cancer

  Anne T. Schneider;Jérémie Gautheron;Maria Feoktistova;Christoph Roderburg

  147
  Citations

• Absence of RIPK3 predicts necroptosis resistance in malignant melanoma

  P Geserick;J Wang;J Wang;R Schilling;S Horn

  146
  Citations

• Suppression of cFLIP is sufficient to sensitize human melanoma cells to TRAIL- and CD95L-mediated apoptosis.

  P Geserick;C Drewniok;M Hupe;T L Haas

  145
  Citations

• Maturation of dendritic cells leads to up-regulation of cellular FLICE-inhibitory protein and concomitant down-regulation of death ligand-mediated apoptosis.

  Martin Leverkus;Martin Leverkus;Henning Walczak;Henning Walczak;Alex McLellan;Alex McLellan;Hans-Werner Fries;Hans-Werner Fries

  135
  Citations