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Medicine

D-Index
85
Citations
45326
World Ranking
14355
National Ranking
758

Overview

Jochen Utikal is affiliated with the German Cancer Research Center in Germany and has contributed extensively to the fields of medicine, biochemistry, genetics, and molecular biology. Their research spans several subfields, with a particular focus on oncology, molecular biology, immunology, artificial intelligence, and epidemiology.

Their work frequently addresses topics related to cutaneous melanoma detection and management, melanoma and MAPK pathways, cancer immunotherapy and biomarkers, and immunotherapy and immune responses. Other prominent research areas include artificial intelligence applications in cancer detection, CAR-T cell therapy research, and the role of immune cells in cancer.

Jochen Utikal has coauthored studies with researchers such as Dirk Schadendorf, Friedegund Meier, Selma Ugurel, Sebastian Haferkamp, and Ralf Gutzmer, each with numerous collaborative publications.

Notable recent papers include:

  • "An RNA vaccine drives immunity in checkpoint-inhibitor-treated melanoma", 2020, Nature
  • "IL-6 as a major regulator of MDSC activity and possible target for cancer immunotherapy", 2020, Cellular Immunology
  • "Myeloid-derived suppressor cells in cancer and cancer therapy", 2024, Nature Reviews Clinical Oncology
  • "Adjuvant nivolumab plus ipilimumab or nivolumab monotherapy versus placebo in patients with resected stage IV melanoma with no evidence of disease (IMMUNED): a randomised, double-blind, placebo-controlled, phase 2 trial", 2020, The Lancet
  • "Skin cancer classification via convolutional neural networks: systematic review of studies involving human experts", 2021, European Journal of Cancer

Their work has been published in various scientific journals, with frequent publications in:

  • European Journal of Cancer
  • Cancers
  • JDDG Journal der Deutschen Dermatologischen Gesellschaft
  • Journal for ImmunoTherapy of Cancer
  • Annals of Oncology

Jochen Utikal has also contributed to book publications, including a work titled Ethical Challenges in Cancer Diagnosis and Therapy, published by Springer Science+Business Media in 2021.

Best Publications

  • Genomic correlates of response to CTLA-4 blockade in metastatic melanoma

    Eliezer M. Van Allen;Eliezer M. Van Allen;Diana Miao;Diana Miao;Bastian Schilling;Sachet A. Shukla;Sachet A. Shukla

  • Personalized RNA mutanome vaccines mobilize poly-specific therapeutic immunity against cancer

    Ugur Sahin;Evelyna Derhovanessian;Matthias Miller;Björn-Philipp Kloke

  • Improved Survival with MEK Inhibition in BRAF-Mutated Melanoma

    Keith T. Flaherty;Caroline Robert;Peter Hersey;Paul Nathan

  • Induced pluripotent stem cells generated without viral integration

    Matthias Stadtfeld;Masaki Nagaya;Masaki Nagaya;Jochen Utikal;Gordon Weir;Gordon Weir

  • Directly Reprogrammed Fibroblasts Show Global Epigenetic Remodeling and Widespread Tissue Contribution

    Nimet Maherali;Rupa Sridharan;Wei Xie;Jochen Utikal

  • Improved survival with MEK Inhibition in BRAF-mutated melanoma for the METRIC Study Group

    K T Flaherty;C Robert;P Hersey;P Nathan;P Nathan

  • Combined BRAF and MEK Inhibition versus BRAF Inhibition Alone in Melanoma

    G.V. Long;D. Stroyakovskiy;H. Gogas;E. Levchenko

  • Dabrafenib and trametinib versus dabrafenib and placebo for Val600 BRAF-mutant melanoma: a multicentre, double-blind, phase 3 randomised controlled trial

    Georgina V. Long;Georgina V. Long;Daniil Stroyakovskiy;Helen Gogas;Evgeny Levchenko

  • Immortalization eliminates a roadblock during cellular reprogramming into iPS cells

    Jochen Utikal;Jose M. Polo;Matthias Stadtfeld;Nimet Maherali

  • Integrative molecular and clinical modeling of clinical outcomes to PD1 blockade in patients with metastatic melanoma

    David Liu;David Liu;Bastian Schilling;Bastian Schilling;Derek Liu;Derek Liu;Antje Sucker

  • An RNA vaccine drives immunity in checkpoint-inhibitor-treated melanoma.

    Ugur Sahin;Petra Oehm;Evelyna Derhovanessian;Robert A. Jabulowsky

  • Immunosuppression mediated by myeloid-derived suppressor cells (MDSCs) during tumour progression

    Christopher Groth;Christopher Groth;Xiaoying Hu;Xiaoying Hu;Rebekka Weber;Rebekka Weber;Viktor Fleming;Viktor Fleming

  • A high-efficiency system for the generation and study of human induced pluripotent stem cells.

    Nimet Maherali;Tim Ahfeldt;Tim Ahfeldt;Alessandra Rigamonti;Jochen Utikal

  • Cutaneous, gastrointestinal, hepatic, endocrine, and renal side-effects of anti-PD-1 therapy.

    Lars Hofmann;Andrea Forschner;Carmen Loquai;Simone M. Goldinger

  • Dabrafenib plus trametinib versus dabrafenib monotherapy in patients with metastatic BRAF V600E/K-mutant melanoma: long-term survival and safety analysis of a phase 3 study.

    G. V. Long;K. T. Flaherty;D. Stroyakovskiy;H. Gogas

  • Neurological, respiratory, musculoskeletal, cardiac and ocular side-effects of anti-PD-1 therapy.

    Lisa Zimmer;Simone M. Goldinger;Lars Hofmann;Carmen Loquai

  • Deep learning outperformed 136 of 157 dermatologists in a head-to-head dermoscopic melanoma image classification task

    Titus J. Brinker;Titus J. Brinker;Achim Hekler;Alexander H. Enk;Joachim Klode

  • Myeloid-Derived Suppressor Cells Hinder the Anti-Cancer Activity of Immune Checkpoint Inhibitors.

    Rebekka Weber;Rebekka Weber;Viktor Fleming;Viktor Fleming;Xiaoying Hu;Xiaoying Hu;Vasyl Nagibin;Vasyl Nagibin

  • Reprogramming of Neural Progenitor Cells into Induced Pluripotent Stem Cells in the Absence of Exogenous Sox2 Expression

    Sarah Eminli;Sarah Eminli;Jochen Utikal;Jochen Utikal;Katrin Arnold;Katrin Arnold;Rudolf Jaenisch

  • Integrative molecular and clinical modeling of clinical outcomes to PD1 blockade in patients with metastatic melanoma

    David Liu;Bastian Schilling;Derek Liu;Antje Sucker

Frequent Co-Authors

Dirk Schadendorf
Dirk Schadendorf University of Duisburg-Essen
Viktor Umansky
Viktor Umansky Heidelberg University
Sergij Goerdt
Sergij Goerdt Heidelberg University
Ralf Gutzmer
Ralf Gutzmer Hannover Medical School
Axel Hauschild
Axel Hauschild Kiel University
Carola Berking
Carola Berking Ludwig-Maximilians-Universität München
Claus Garbe
Claus Garbe University of Tübingen
Christof von Kalle
Christof von Kalle Charité - University Medicine Berlin
Alexander Enk
Alexander Enk Heidelberg University

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