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Biology and Biochemistry
Japan
2026

D-Index & Metrics

Biology and Biochemistry

D-Index
98
Citations
32842
World Ranking
1677
National Ranking
93

Medicine

D-Index
99
Citations
33035
World Ranking
8654
National Ranking
226

Research.com Recognitions

  • 2026 - Research.com Biology and Biochemistry in Japan Leader Award
  • 2025 - Research.com Biology and Biochemistry in Japan Leader Award

Overview

Motohiro Takeya is affiliated with Kumamoto University in Japan and has research contributions primarily in the fields of Immunology and Microbiology, Medicine, and Biochemistry, Genetics and Molecular Biology. Their work intersects various subfields, including Immunology, Pathology and Forensic Medicine, Surgery, Molecular Biology, and Genetics.

Takeya's research topics cover a range of biomedical areas such as:

  • Immune Cell Function and Interaction
  • Lymphoma Diagnosis and Treatment
  • Immunotherapy and Immune Responses
  • Testicular diseases and treatments
  • Renal and related cancers
  • Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities

The scientist has contributed to peer-reviewed articles published in notable journals like Cancers and Cancer Science. Two recent papers include:

  • A Novel Cytological Model of B-Cell/Macrophage Biphenotypic Cell Hodgkin Lymphoma in Ganp-Transgenic Mice (2020, Cancers)
  • Testicular teratomagenesis from primordial germ cells with overexpression of germinal center-associated nuclear protein (2022, Cancer Science)

Academic collaboration plays a significant role in Takeya's research. Frequent co-authors include:

  • Yasuhiro Sakai
  • Andri Rezano
  • Yoshiaki Kawashima
  • Nobuo Sakaguchi
  • K. Kuwahara

Takeya's research contributions span molecular and clinical aspects relevant to immunology and oncology, focusing on cellular models and pathological mechanisms underlying diseases such as lymphoma and testicular cancer. This multidisciplinary approach combines clinical insights with molecular biology techniques to address complex biomedical challenges.

Best Publications

  • A role for macrophage scavenger receptors in atherosclerosis and susceptibility to infection

    Hiroshi Suzuki;Hiroshi Suzuki;Yukiko Kurihara;Motohiro Takeya;Nobuo Kamada

  • DC-STAMP is essential for cell–cell fusion in osteoclasts and foreign body giant cells

    Mitsuru Yagi;Takeshi Miyamoto;Yumi Sawatani;Katsuya Iwamoto

  • Possible involvement of the M2 anti-inflammatory macrophage phenotype in growth of human gliomas

    Y Komohara;K Ohnishi;J Kuratsu;M Takeya

  • Tumor-associated macrophages: Potential therapeutic targets for anti-cancer therapy.

    Yoshihiro Komohara;Yukio Fujiwara;Koji Ohnishi;Motohiro Takeya

  • Clinical significance of macrophage heterogeneity in human malignant tumors

    Yoshihiro Komohara;Masahisa Jinushi;Motohiro Takeya

  • Deletion of LOX-1 Reduces Atherogenesis in LDLR Knockout Mice Fed High Cholesterol Diet

    Jawahar L. Mehta;Nobuhito Sanada;Chang Ping Hu;Jiawei Chen

  • Histopathologic pulmonary changes from mechanical ventilation at high peak airway pressures

    Kyoji Tsuno;Kazunori Miura;Motohiro Takeya;Theodor Kolobow

  • Increased Adiponectin Secretion by Highly Purified Eicosapentaenoic Acid in Rodent Models of Obesity and Human Obese Subjects

    Michiko Itoh;Takayoshi Suganami;Noriko Satoh;Kanami Tanimoto-Koyama

  • Immunohistochemical and ultrastructural detection of advanced glycation end products in atherosclerotic lesions of human aorta with a novel specific monoclonal antibody.

    S. Kume;M. Takeya;T. Mori;N. Araki

  • Detection of monocyte chemoattractant protein-1 in human atherosclerotic lesions by an anti-monocyte chemoattractant protein-1 monoclonal antibody

    Motohiro Takeya;Teizo Yoshimura;Edward J. Leonard;Kiyoshi Takahashi

  • A novel human CC chemokine PARC that is most homologous to macrophage-inflammatory protein-1 alpha/LD78 alpha and chemotactic for T lymphocytes, but not for monocytes.

    K Hieshima;T Imai;M Baba;K Shoudai

  • Hypertensive Myocardial Fibrosis and Diastolic Dysfunction: Another Model of Inflammation?

    Fumitaka Kuwahara;Hisashi Kai;Keisuke Tokuda;Motohiro Takeya

  • Blockade of CCR2 ameliorates progressive fibrosis in kidney.

    Kiyoki Kitagawa;Takashi Wada;Kengo Furuichi;Hiroyuki Hashimoto

  • A dipeptidyl peptidase-4 inhibitor, des-fluoro-sitagliptin, improves endothelial function and reduces atherosclerotic lesion formation in apolipoprotein E-deficient mice.

    Junichi Matsubara;Seigo Sugiyama;Koichi Sugamura;Taishi Nakamura

  • Significance of alternatively activated macrophages in patients with intrahepatic cholangiocarcinoma

    Horlad Hasita;Yoshihiro Komohara;Hirohisa Okabe;Toshiro Masuda

  • Macrophage infiltration and its prognostic relevance in clear cell renal cell carcinoma

    Yoshihiro Komohara;Horlad Hasita;Koji Ohnishi;Yukio Fujiwara

  • Angiopoietin-related growth factor antagonizes obesity and insulin resistance

    Yuichi Oike;Masaki Akao;Kunio Yasunaga;Toshimasa Yamauchi

  • Phase I clinical study applying autologous immunological effector cells transfected with the interleukin-2 gene in patients with metastatic renal cancer, colorectal cancer and lymphoma.

    I. G. H. Schmidt-Wolf;S. Finke;B. Trojaneck;A. Denkena

  • CCR2 Signaling Contributes to Ischemia-Reperfusion Injury in Kidney

    Kengo Furuichi;Takashi Wada;Yasunori Iwata;Kiyoki Kitagawa

  • MARCO Is the Major Binding Receptor for Unopsonized Particles and Bacteria on Human Alveolar Macrophages

    Mohamed S. Arredouani;Aiyappa Palecanda;Henry Koziel;Yuh Ching Huang

Frequent Co-Authors

Kiyoshi Takahashi
Kiyoshi Takahashi Kumamoto University
Yoshihiro Komohara
Yoshihiro Komohara Kumamoto University
Seikoh Horiuchi
Seikoh Horiuchi Kumamoto University
Hiroshi Suzuki
Hiroshi Suzuki Obihiro University of Agriculture and Veterinary Medicine
Kiyoshi Takatsuki
Kiyoshi Takatsuki Kumamoto University
Hisao Ogawa
Hisao Ogawa Kumamoto University
Tatsuhiko Kodama
Tatsuhiko Kodama University of Tokyo
Yuichi Oike
Yuichi Oike Kumamoto University
Kimi Araki
Kimi Araki Kumamoto University
Ryoji Nagai
Ryoji Nagai Tokai University

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