World's Best Scientists 2026 revealed!
Ryoji Nagai

Ryoji Nagai

D-Index & Metrics

Biology and Biochemistry

D-Index
64
Citations
11250
World Ranking
9901
National Ranking
663

Ryoji Nagai publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Ryoji Nagai sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 215 publications — 56th percentile

56% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Ryoji Nagai D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Ryoji Nagai sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 64 D-Index — 52nd percentile

52% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Ryoji Nagai is affiliated with Tokai University in Japan and has contributed extensively to research primarily in the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their work spans several subfields including Clinical Biochemistry, Endocrinology, Diabetes and Metabolism, Molecular Biology, Pathology and Forensic Medicine, and Physiology.

The scientist's research prominently addresses Advanced Glycation End Products (AGEs) with a considerable number of publications focused on this topic. Other significant research areas include Natural Antidiabetic Agents Studies, Biochemical effects in animals, Alcohol Consumption and Health Effects, Neurological Disorders and Treatments, Diabetes, Cardiovascular Risks, and Lipoproteins, as well as Sulfur Compounds in Biology.

Frequent co-authors in Nagai's research include Hikari Sugawa, who has collaborated on 17 publications, Yuki Tominaga with 5 collaborations, Nana Katsuta with 5, Mime Nagai with 5, and Sayuri Kato with 4 joint works.

Several important papers highlight Nagai's contribution to scientific literature:

  • Intracellular Accumulation of Advanced Glycation End Products Induces Osteoblast Apoptosis Via Endoplasmic Reticulum Stress, 2020, Journal of Bone and Mineral Research
  • Mass spectrometric quantitation of AGEs and enzymatic crosslinks in human cancellous bone, 2020, Scientific Reports
  • RAGE activation in macrophages and development of experimental diabetic polyneuropathy, 2022, JCI Insight
  • Drosera tokaiensis extract containing multiple phenolic compounds inhibits the formation of advanced glycation end-products, 2020, Archives of Biochemistry and Biophysics
  • Trapa bispinosa Roxb. extract lowers advanced glycation end-products and increases live births in older patients with assisted reproductive technology: a randomized controlled trial, 2021, Reproductive Biology and Endocrinology

Nagai frequently publishes in recognized venues, including Scientific Reports, Free Radical Biology and Medicine, Journal of Clinical Biochemistry and Nutrition, Glycoconjugate Journal, and Journal of Diabetes Investigation. These journals reflect the scientist's focus on biochemical and clinical aspects of disease processes.

Best Publications

  • Accumulation of advanced glycation end products in the peritoneal vasculature of continuous ambulatory peritoneal dialysis patients with low ultra-filtration.

    Kazuho Honda;Kosaku Nitta;Shigeru Horita;Wako Yumura

  • Cd36, a member of the class b scavenger receptor family, as a receptor for advanced glycation end products.

    Nobutaka Ohgami;Ryoji Nagai;Mamoru Ikemoto;Hiroyuki Arai

  • Morphological evidence for lipid peroxidation and protein glycoxidation in spinal cords from sporadic amyotrophic lateral sclerosis patients

    Noriyuki Shibata;Ryoji Nagai;Koji Uchida;Seikoh Horiuchi

  • The relationship between accumulation of advanced glycation end products and expression of vascular endothelial growth factor in human diabetic retinas.

    T. Murata;R. Nagai;T. Ishibashi;H. Inomata

  • Chelation: A Fundamental Mechanism of Action of AGE Inhibitors, AGE Breakers, and Other Inhibitors of Diabetes Complications

    Ryoji Nagai;David B. Murray;Thomas O. Metz;John W. Baynes

  • Advanced Oxidation Protein Products Accelerate Atherosclerosis Through Promoting Oxidative Stress and Inflammation

    Shang Xi Liu;Fan Fan Hou;Zhi Jian Guo;Ryoji Nagai

  • Advanced oxidation protein products activate vascular endothelial cells via a RAGE-mediated signaling pathway.

    Zhi Jian Guo;Hong Xin Niu;Fan Fan Hou;Lu Zhang

  • Glycolaldehyde, a reactive intermediate for advanced glycation end products, plays an important role in the generation of an active ligand for the macrophage scavenger receptor

    Ryoji Nagai;Kenshi Matsumoto;Xia Ling;Hiroshi Suzuki

  • Advanced glycation end products in age-related macular degeneration

    Tatsuro Ishibashi;Toshinori Murata;Masanori Hangai;Ryoji Nagai

  • Hydroxyl radical mediates N epsilon-(carboxymethyl)lysine formation from Amadori product.

    Ryoji Nagai;Kazuyoshi Ikeda;Takayuki Higashi;Hiroyuki Sano

  • Scavenger Receptor Class B Type I-mediated Reverse Cholesterol Transport Is Inhibited by Advanced Glycation End Products

    Nobutaka Ohgami;Ryoji Nagai;Akira Miyazaki;Mamoru Ikemoto

  • Involvement of a gut–retina axis in protection against dietary glycemia-induced age-related macular degeneration

    Sheldon Rowan;Shuhong Jiang;Tal Korem;Jedrzej Szymanski

  • S-(2-Succinyl)cysteine: a novel chemical modification of tissue proteins by a Krebs cycle intermediate.

    Nathan L Alderson;Yuping Wang;Matthew Blatnik;Norma Frizzell

  • Identification in human atherosclerotic lesions of GA-pyridine, a novel structure derived from glycolaldehyde-modified proteins.

    Ryoji Nagai;Cristina Miki Hayashi;Ling Xia;Motohiro Takeya

  • Peroxynitrite Induces Formation of Nε-(Carboxymethyl)Lysine by the Cleavage of Amadori Product and Generation of Glucosone and Glyoxal From Glucose: Novel Pathways for Protein Modification by Peroxynitrite

    Ryoji Nagai;Yuka Unno;Miki Cristina Hayashi;Shuichi Masuda

  • CD36, serves as a receptor for advanced glycation endproducts (AGE).

    Nobutaka Ohgami;Ryoji Nagai;Mamoru Ikemoto;Hiroyuki Arai

  • Lectin-like oxidized low density lipoprotein receptor-1 (LOX-1) serves as an endothelial receptor for advanced glycation end products (AGE)

    Tadashi Jono;Akira Miyazaki;Ryoji Nagai;Tatsuya Sawamura

  • Glycation of a food allergen by the Maillard reaction enhances its T-cell immunogenicity: role of macrophage scavenger receptor class A type I and II

    Anne Ilchmann;Sven Burgdorf;Stephan Scheurer;Zoe Waibler

  • Increased advanced glycation end products in atherosclerotic lesions of patients with end-stage renal disease.

    Noriyuki Sakata;Yoshinobu Imanaga;Jing Meng;Yutaka Tachikawa

  • Succination of protein thiols during adipocyte maturation: a biomarker of mitochondrial stress.

    Ryoji Nagai;Jonathan W. Brock;Matthew Blatnik;John E. Baatz

Frequent Co-Authors

Seikoh Horiuchi
Seikoh Horiuchi Kumamoto University
Masaki Otagiri
Masaki Otagiri Sojo University
Motohiro Takeya
Motohiro Takeya Kumamoto Health Science University
John W. Baynes
John W. Baynes University of South Carolina
Suzanne R. Thorpe
Suzanne R. Thorpe University of South Carolina
Toru Maruyama
Toru Maruyama Kumamoto University
Hiroshi Suzuki
Hiroshi Suzuki Obihiro University of Agriculture and Veterinary Medicine
Bård Smedsrød
Bård Smedsrød University of Tromsø - The Arctic University of Norway
Felipe Dal-Pizzol
Felipe Dal-Pizzol Universidade do Extremo Sul Catarinense
Shiro Amano
Shiro Amano University of Tokyo

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