World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
81
Citations
24611
World Ranking
3877
National Ranking
1923

Research.com Recognitions

  • 2015 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Vincent M. Monnier is affiliated with Case Western Reserve University in the United States. Their research predominantly spans the fields of Biochemistry, Genetics and Molecular Biology, and Medicine, with significant focus on subfields such as Clinical Biochemistry, Molecular Biology, Endocrinology, Diabetes and Metabolism, Ophthalmology, and Radiology, Nuclear Medicine and Imaging.

The scientist's main topics of research include:

  • Advanced Glycation End Products research
  • Connexins and lens biology
  • Diabetes Management and Research
  • Heme Oxygenase-1 and Carbon Monoxide
  • Diabetes, Cardiovascular Risks, and Lipoproteins
  • Redox biology and oxidative stress
  • S100 Proteins and Annexins

Frequent co-authors collaborating with Vincent M. Monnier are:

  • Xingjun Fan
  • David R. Sell
  • Caili Hao
  • Benlian Wang
  • Kristine Bech Holte

Their work has been published in a variety of scientific venues, including:

  • Experimental Eye Research
  • BMJ Open Diabetes Research & Care
  • Science Advances
  • Aging Cell
  • Frontiers in Pharmacology

Notable recent papers authored or co-authored by Vincent M. Monnier include:

  • Protein posttranslational modification (PTM) by glycation: Role in lens aging and age-related cataractogenesis (2021, Experimental Eye Research)
  • Plasma advanced glycation end products and the subsequent risk of microvascular complications in type 1 diabetes in the DCCT/EDIC (2022, BMJ Open Diabetes Research & Care)
  • Vitamin C is a source of oxoaldehyde and glycative stress in age-related cataract and neurodegenerative diseases (2020, Aging Cell)
  • α-Crystallin chaperone mimetic drugs inhibit lens γ-crystallin aggregation: Potential role for cataract prevention (2022, Journal of Biological Chemistry)
  • Prevention of age-related truncation of γ-glutamylcysteine ligase catalytic subunit (GCLC) delays cataract formation (2024, Science Advances)

Vincent M. Monnier was recognized as a Fellow of the American Association for the Advancement of Science (AAAS) in 2015.

Best Publications

  • Structure Elucidation of a Senescence Cross-Link from Human Extracellular Matrix: Implication of Pentoses in the Aging Process *

    D R Sell;V M Monnier

  • Nonenzymatic browning in vivo: possible process for aging of long-lived proteins.

    Vincent M. Monnier;Anthony Cerami

  • Advanced Maillard reaction end products are associated with Alzheimer disease pathology

    Mark A. Smith;Shinji Taneda;Peggy L. Richey;Satoshi Miyata

  • Accelerated age-related browning of human collagen in diabetes mellitus

    Vincent M. Monnier;Robert R. Kohn;Anthony Cerami

  • Relation between Complications of Type I Diabetes Mellitus and Collagen-Linked Fluorescence

    Vincent M. Monnier;Vasanth Vishwanath;Kay E. Frank;Craig A. Elmets

  • Mechanism of Protein Modification by Glyoxal and Glycolaldehyde, Reactive Intermediates of the Maillard Reaction

    Marcus A. Glomb;Vincent M. Monnier

  • Radical AGEing in Alzheimer's disease

    Mark A. Smith;Lawrence M. Sayre;Vincent M. Monnier;George Perry

  • Immunohistochemical colocalization of glycoxidation products and lipid peroxidation products in diabetic renal glomerular lesions. Implication for glycoxidative stress in the pathogenesis of diabetic nephropathy.

    K Horie;T Miyata;K Maeda;S Miyata

  • Diabetic cataract formation: potential role of glycosylation of lens crystallins.

    Victor J. Stevens;Carol A. Rouzer;Vincent M. Monnier;Anthony Cerami

  • Mechanism of formation of the Maillard protein cross-link pentosidine. Glucose, fructose, and ascorbate as pentosidine precursors.

    Sunitha K. Grandhee;Vincent M. Monnier

  • Nonenzymatic glycosylation, the Maillard reaction and the aging process.

    Vincent M. Monnier

  • Glycation of mitochondrial proteins from diabetic rat kidney is associated with excess superoxide formation

    Mariana G. Rosca;Tiberiu G. Mustata;Michael T. Kinter;Aylin M. Ozdemir

  • Aging of proteins: immunological detection of a glucose-derived pyrrole formed during maillard reaction in vivo.

    F. Hayase;Ram H Nagaraj;S. Miyata;F. G. Njoroge

  • Maillard reaction-mediated molecular damage to extracellular matrix and other tissue proteins in diabetes, aging, and uremia.

    Vincent M Monnier;David R Sell;Ramanakoppa H Nagaraj;Satoshi Miyata

  • End-stage renal disease and diabetes catalyze the formation of a pentose-derived crosslink from aging human collagen.

    David R. Sell;Vincent M. Monnier

  • Molecular basis of arterial stiffening: role of glycation - a mini-review.

    David R. Sell;Vincent M. Monnier

  • High correlation between pentosidine protein crosslinks and pigmentation implicates ascorbate oxidation in human lens senescence and cataractogenesis

    Ramanakoppa H. Nagaraj;David R. Sell;Malladi Prabhakaram;Beryl J. Ortwerth

  • Immunohistochemical detection of advanced glycosylation end products in diabetic tissues using monoclonal antibody to pyrraline.

    Satoshi Miyata;Vincent Monnier

  • Longevity and the genetic determination of collagen glycoxidation kinetics in mammalian senescence.

    David R. Sell;Mark A. Lane;Wesley A. Johnson;Edward J. Masoro

  • Chromatographic quantitation of plasma and erythrocyte pentosidine in diabetic and uremic subjects.

    Patrizio Odetti;Jack Fogarty;David R Sell;Vincent M Monnier

Frequent Co-Authors

Mark A. Smith
Mark A. Smith Case Western Reserve University
George Perry
George Perry The University of Texas at San Antonio
Lawrence M. Sayre
Lawrence M. Sayre Case Western Reserve University
John M. Lachin
John M. Lachin George Washington University
Anthony Cerami
Anthony Cerami Araim Pharmaceuticals (United States)
Lloyd Paul Aiello
Lloyd Paul Aiello Harvard University
George L. King
George L. King Harvard University
Timothy S. Kern
Timothy S. Kern University of California, Irvine
Monika Pischetsrieder
Monika Pischetsrieder University of Erlangen-Nuremberg
Julia A. Kornfield
Julia A. Kornfield California Institute of Technology

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