What is he best known for?
The fields of study he is best known for:
- Enzyme
- Gene
- Internal medicine
His main research concerns Biochemistry, Proteasome, Oxidative stress, Protein oxidation and Cell biology.
His study in Lipid peroxidation, Intracellular, In vitro, Peroxynitrite and Hydrogen peroxide is carried out as part of his studies in Biochemistry.
His study in Proteasome is interdisciplinary in nature, drawing from both Ubiquitin, Protein degradation, Reactive oxygen species, Oxidative phosphorylation and Proteolysis.
His Oxidative stress research includes themes of Bioinformatics, Molecular biology, Glycation, Ageing and Proteostasis.
His studies in Protein oxidation integrate themes in fields like Protein aggregation, Senescence, Cell aging, Nuclear protein and Protein turnover.
His research in Cell biology focuses on subjects like Viability assay, which are connected to ATP hydrolysis.
His most cited work include:
- Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (4170 citations)
- Degradation of oxidized proteins in mammalian cells. (765 citations)
- Role of advanced glycation end products in cellular signaling (526 citations)
What are the main themes of his work throughout his whole career to date?
Tilman Grune spends much of his time researching Biochemistry, Oxidative stress, Proteasome, Cell biology and Protein oxidation.
His research in Lipid peroxidation, Proteolysis, Intracellular, Oxidative phosphorylation and Metabolism are components of Biochemistry.
His Oxidative stress research includes elements of Glutathione and Antioxidant.
His biological study spans a wide range of topics, including Nuclear protein, Ubiquitin, Protein degradation and Cytosol.
The study incorporates disciplines such as Autophagy and Lipofuscin in addition to Cell biology.
His Protein oxidation study combines topics from a wide range of disciplines, such as Reactive oxygen species, Protein turnover and Protein Carbonylation.
He most often published in these fields:
- Biochemistry (51.02%)
- Oxidative stress (34.69%)
- Proteasome (29.31%)
What were the highlights of his more recent work (between 2015-2021)?
- Internal medicine (18.37%)
- Oxidative stress (34.69%)
- Endocrinology (15.96%)
In recent papers he was focusing on the following fields of study:
The scientist’s investigation covers issues in Internal medicine, Oxidative stress, Endocrinology, Cell biology and Proteasome.
Tilman Grune usually deals with Internal medicine and limits it to topics linked to Type 2 diabetes and Insulin.
The concepts of his Oxidative stress study are interwoven with issues in Adipogenesis, Glutathione, Mitochondrion and Metabolism.
His Cell biology research is multidisciplinary, relying on both Autophagy, Lipofuscin and Skeletal muscle.
His Autophagy research focuses on Senescence and how it connects with PI3K/AKT/mTOR pathway.
His Proteasome research focuses on Protein oxidation and how it relates to Protein degradation.
Between 2015 and 2021, his most popular works were:
- Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (4170 citations)
- Happily (n)ever after: Aging in the context of oxidative stress, proteostasis loss and cellular senescence. (133 citations)
- European contribution to the study of ROS : a summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS) (132 citations)
In his most recent research, the most cited papers focused on:
- Enzyme
- Gene
- Internal medicine
Tilman Grune mainly investigates Oxidative stress, Cell biology, Internal medicine, Proteasome and Autophagy.
Biochemistry covers Tilman Grune research in Oxidative stress.
His study in the fields of Protein aggregation, Proteostasis and Senescence under the domain of Cell biology overlaps with other disciplines such as Humanities.
His Internal medicine study which covers Endocrinology that intersects with Carotenoid and Micronutrient.
His work deals with themes such as Cancer research, Hsp70, Metabolism and Protein oxidation, which intersect with Proteasome.
His Autophagy study incorporates themes from PI3K/AKT/mTOR pathway, Computational biology and Programmed cell death.
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