D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Molecular Biology D-index 64 Citations 11,653 208 World Ranking 1143 National Ranking 81

Overview

What is he best known for?

The fields of study Alexander Bürkle is best known for:

  • DNA
  • Gene
  • DNA repair

His research combines Biochemistry and DNA damage. Biochemistry and DNA glycosylase are frequently intertwined in his study. His study deals with a combination of DNA glycosylase and Base excision repair. He carries out multidisciplinary research, doing studies in Base excision repair and DNA damage. Alexander Bürkle incorporates DNA and Computational biology in his research. He connects Computational biology with DNA in his research. He combines DNA repair and Telomere in his research. His work often combines Telomere and DNA repair studies. Alexander Bürkle connects Molecular biology with Recombinant DNA in his study.

His most cited work include:

  • Interference by toxic metal ions with DNA repair processes and cell cycle control: molecular mechanisms. (247 citations)
  • Overproduction of the poly(ADP-ribose) polymerase DNA-binding domain blocks alkylation-induced DNA repair synthesis in mammalian cells. (233 citations)
  • Stress, DNA damage and ageing — an integrative approach (178 citations)

What are the main themes of his work throughout his whole career to date

Alexander Bürkle carries out multidisciplinary research, doing studies in Molecular biology and Transfection. He undertakes interdisciplinary study in the fields of Transfection and Cell culture through his works. He integrates many fields in his works, including Cell culture and Gene. In his works, he undertakes multidisciplinary study on Gene and Recombinant DNA. Alexander Bürkle performs integrative study on Recombinant DNA and Molecular biology in his works. He frequently studies issues relating to DNA replication and Genetics. His work on DNA damage expands to the thematically related Biochemistry. His research combines Nucleotide excision repair and DNA damage. He performs multidisciplinary study in Nucleotide excision repair and DNA repair in his work.

Alexander Bürkle most often published in these fields:

  • Molecular biology (72.22%)
  • Genetics (72.22%)
  • Biochemistry (66.67%)

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Physiology and pathophysiology of poly(ADP-ribosyl)ation.

Alexander Bürkle.
BioEssays (2001)

397 Citations

Poly(ADP‐ribose)

Alexander Bürkle.
FEBS Journal (2005)

372 Citations

Poly(ADP-ribose) polymerase activity in mononuclear leukocytes of 13 mammalian species correlates with species-specific life span

Karlheinz Grube;Alexander Burkle.
Proceedings of the National Academy of Sciences of the United States of America (1992)

366 Citations

Inactivation of the poly(ADP-ribose) polymerase gene affects oxygen radical and nitric oxide toxicity in islet cells

Birgit Heller;Zhao-Qi Wang;Erwin F. Wagner;Jürgen Radons.
Journal of Biological Chemistry (1995)

352 Citations

Interference by toxic metal ions with DNA repair processes and cell cycle control: molecular mechanisms.

A Hartwig;M Asmuss;I Ehleben;U Herzer.
Environmental Health Perspectives (2002)

335 Citations

DNA amplification of adeno-associated virus as a response to cellular genotoxic stress.

Yalkinoglu Ao;Heilbronn R;Bürkle A;Schlehofer.
Cancer Research (1988)

294 Citations

Overproduction of the poly(ADP-ribose) polymerase DNA-binding domain blocks alkylation-induced DNA repair synthesis in mammalian cells.

M. Molinete;W. Vermeulen;A. Bürkle;J. Menissier-De Murcia.
The EMBO Journal (1993)

284 Citations

Lethal recessive myelin toxicity of prion protein lacking its central domain

Frank Baumann;Markus Tolnay;Christine Brabeck;Jens Pahnke.
The EMBO Journal (2007)

278 Citations

Nitric oxide toxicity in islet cells involves poly(ADP-ribose) polymerase activation and concomitant NAD+ depletion.

J. Radons;B. Heller;A. Burkle;B. Hartmann.
Biochemical and Biophysical Research Communications (1994)

262 Citations

Stress, DNA damage and ageing -- an integrative approach.

von Zglinicki T;Bürkle A;Kirkwood Tb.
Experimental Gerontology (2001)

246 Citations

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