His research combines Biochemistry and DNA damage. Biochemistry and DNA glycosylase are frequently intertwined in his study. His study deals with a combination of DNA glycosylase and Base excision repair. He carries out multidisciplinary research, doing studies in Base excision repair and DNA damage. Alexander Bürkle incorporates DNA and Computational biology in his research. He connects Computational biology with DNA in his research. He combines DNA repair and Telomere in his research. His work often combines Telomere and DNA repair studies. Alexander Bürkle connects Molecular biology with Recombinant DNA in his study.
Alexander Bürkle carries out multidisciplinary research, doing studies in Molecular biology and Transfection. He undertakes interdisciplinary study in the fields of Transfection and Cell culture through his works. He integrates many fields in his works, including Cell culture and Gene. In his works, he undertakes multidisciplinary study on Gene and Recombinant DNA. Alexander Bürkle performs integrative study on Recombinant DNA and Molecular biology in his works. He frequently studies issues relating to DNA replication and Genetics. His work on DNA damage expands to the thematically related Biochemistry. His research combines Nucleotide excision repair and DNA damage. He performs multidisciplinary study in Nucleotide excision repair and DNA repair in his work.
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Physiology and pathophysiology of poly(ADP-ribosyl)ation.
FEBS Journal (2005)
Poly(ADP-ribose) polymerase activity in mononuclear leukocytes of 13 mammalian species correlates with species-specific life span
Karlheinz Grube;Alexander Burkle.
Proceedings of the National Academy of Sciences of the United States of America (1992)
Inactivation of the poly(ADP-ribose) polymerase gene affects oxygen radical and nitric oxide toxicity in islet cells
Birgit Heller;Zhao-Qi Wang;Erwin F. Wagner;Jürgen Radons.
Journal of Biological Chemistry (1995)
Interference by toxic metal ions with DNA repair processes and cell cycle control: molecular mechanisms.
A Hartwig;M Asmuss;I Ehleben;U Herzer.
Environmental Health Perspectives (2002)
DNA amplification of adeno-associated virus as a response to cellular genotoxic stress.
Yalkinoglu Ao;Heilbronn R;Bürkle A;Schlehofer.
Cancer Research (1988)
Overproduction of the poly(ADP-ribose) polymerase DNA-binding domain blocks alkylation-induced DNA repair synthesis in mammalian cells.
M. Molinete;W. Vermeulen;A. Bürkle;J. Menissier-De Murcia.
The EMBO Journal (1993)
Lethal recessive myelin toxicity of prion protein lacking its central domain
Frank Baumann;Markus Tolnay;Christine Brabeck;Jens Pahnke.
The EMBO Journal (2007)
Nitric oxide toxicity in islet cells involves poly(ADP-ribose) polymerase activation and concomitant NAD+ depletion.
J. Radons;B. Heller;A. Burkle;B. Hartmann.
Biochemical and Biophysical Research Communications (1994)
Stress, DNA damage and ageing -- an integrative approach.
von Zglinicki T;Bürkle A;Kirkwood Tb.
Experimental Gerontology (2001)
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