World's Best Scientists 2026 revealed!

D-Index & Metrics

Molecular Biology

D-Index
79
Citations
27799
World Ranking
1030
National Ranking
82

Research.com Recognitions

  • 2012 - Member of Academia Europaea

Overview

Zhao-Qi Wang is affiliated with Friedrich Schiller University Jena in Germany. Their research spans multiple domains within biochemistry, genetics, molecular biology, and medicine, with a focus on cellular and molecular mechanisms underlying health and disease.

The main fields of study in their work include:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine

Subfields that characterize their research contributions are:

  • Molecular Biology
  • Oncology
  • Genetics
  • Cell Biology
  • Infectious Diseases

The topics they address prominently include:

  • DNA Repair Mechanisms
  • Microtubule and mitosis dynamics
  • Epigenetics and DNA Methylation
  • Genetics and Neurodevelopmental Disorders
  • PARP inhibition in cancer therapy
  • Mitochondrial Function and Pathology
  • Autophagy in Disease and Therapy

Frequent collaborators in their research are:

  • Christian Marx
  • Tangliang Li
  • Joanna Kirkpatrick
  • Philipp Koch
  • Zhong-Wei Zhou

Wang has published extensively in several notable scientific journals. Frequent publication venues include:

  • Nature Communications
  • Cells
  • International Journal of Molecular Sciences
  • Proceedings of the National Academy of Sciences
  • Scientific Reports

Selected recent papers illustrate the breadth and focus of their work:

  • Microglia mediate neurocognitive deficits by eliminating C1q-tagged synapses in sepsis-associated encephalopathy (2023, Science Advances)
  • ATR is essential for preservation of cell mechanics and nuclear integrity during interstitial migration (2020, Nature Communications)
  • Biogenesis of Iron-Sulfur Clusters and Their Role in DNA Metabolism (2021, Frontiers in Cell and Developmental Biology)
  • Melatonin Attenuates Anoxia/Reoxygenation Injury by Inhibiting Excessive Mitophagy Through the MT2/SIRT3/FoxO3a Signaling Pathway in H9c2 Cells (2020, Drug Design Development and Therapy)
  • PARP1: Liaison of Chromatin Remodeling and Transcription (2022, Cancers)

Best Publications

  • c-Fos: a Key Regulator of Osteoclast-Macrophage Lineage Determination and Bone Remodeling

    Agamemnon E. Grigoriadis;Zhao-Qi Wang;Marco G. Cecchini;Willy Hofstetter

  • Poly(ADP-ribose) polymerase gene disruption renders mice resistant to cerebral ischemia

    Mikael J.L. Eliasson;Kenji Sampei;Allen S. Mandir;Patricia D. Hurn

  • Bone and haematopoietic defects in mice lacking c-fos

    Zhao-Qi Wang;Catherine Ovitt;Agamemnon E. Grigoriadis;Uta Möhle-Steinlein

  • Complete block of early B cell differentiation and altered patterning of the posterior midbrain in mice lacking Pax5/BSAP

    Pavel Urbánek;Zhao-Qi Wang;Ingrid Fetka;Erwin F. Wagner

  • Mice lacking ADPRT and poly(ADP-ribosyl)ation develop normally but are susceptible to skin disease.

    Zhao-Qi Wang;B. Auer;L. Stingl;H. Berghammer

  • Alkylating DNA damage stimulates a regulated form of necrotic cell death

    Wei-Xing Zong;Dara Ditsworth;Daniel E. Bauer;Zhao-Qi Wang

  • Ischemic brain injury is mediated by the activation of poly(ADP-ribose)polymerase

    Matthias Endres;Zhao-Qi Wang;Shobu Namura;Christian Waeber

  • PARP is important for genomic stability but dispensable in apoptosis

    Zhao-Qi Wang;Laura Stingl;Ciaran Morrison;Michael Jantsch

  • Histone acetylation by Trrap–Tip60 modulates loading of repair proteins and repair of DNA double-strand breaks

    Rabih Murr;Joanna I. Loizou;Yun-Gui Yang;Cyrille Cuenin

  • Functions of poly(ADP-ribose) polymerase (PARP) in DNA repair, genomic integrity and cell death.

    Zdenko Herceg;Zhao-Qi Wang

  • Activation and Caspase-mediated Inhibition of PARP: A Molecular Switch between Fibroblast Necrosis and Apoptosis in Death Receptor Signaling

    Marek Los;Malgorzata Mozoluk;Davide Ferrari;Anna Stepczynska

  • Regulation of embryonic growth and lysosomal targeting by the imprinted Igf2/Mpr gene.

    Zhao-Qi Wang;Marion R. Fung;Denise P. Barlow;Erwin F. Wagner

  • Mice lacking the poly(ADP-ribose) polymerase gene are resistant to pancreatic beta-cell destruction and diabetes development induced by streptozocin.

    Volker Burkart;Zhao-Qi Wang;Jürgen Radons;Birgit Heller

  • Poly(ADP-ribose) polymerase activation mediates 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced parkinsonism

    Allen S. Mandir;Serge Przedborski;Vernice Jackson-Lewis;Zhao Qi Wang

  • Human Fanconi anemia monoubiquitination pathway promotes homologous DNA repair

    Koji Nakanishi;Yun-Gui Yang;Andrew J. Pierce;Toshiyasu Taniguchi

  • Osteoblasts are target cells for transformation in c-fos transgenic mice.

    A. E. Grigoriadis;K. Schellander;Zhao-Qi Wang;E. F. Wagner

  • Poly(ADP-ribose) polymerase-deficient mice are protected from streptozotocin-induced diabetes

    Andrew A. Pieper;Daniel J. Brat;Daniel J. Brat;David K. Krug;Crystal C. Watkins

  • Poly(ADP-ribose) Polymerase Null Mouse Cells Synthesize ADP-ribose Polymers

    W M Shieh;J C Amé;M V Wilson;Z Q Wang

  • JunB is essential for mammalian placentation

    Marina Schorpp-Kistner;Zhao Qi Wang;Peter Angel;Erwin F. Wagner

  • Functions of poly(ADP-ribose) polymerase in controlling telomere length and chromosomal stability.

    F d'Adda di Fagagna;M P Hande;W M Tong;P M Lansdorp;P M Lansdorp

Frequent Co-Authors

Erwin F. Wagner
Erwin F. Wagner Medical University of Vienna
Zdenko Herceg
Zdenko Herceg International Agency For Research On Cancer
Yun-Gui Yang
Yun-Gui Yang Chinese Academy of Sciences
Peter M. Lansdorp
Peter M. Lansdorp University of British Columbia
Salvatore Cuzzocrea
Salvatore Cuzzocrea University of Messina
Stephen P. Jackson
Stephen P. Jackson University of Cambridge
Ted M. Dawson
Ted M. Dawson Johns Hopkins University School of Medicine
Valina L. Dawson
Valina L. Dawson Johns Hopkins University School of Medicine
Maria Jasin
Maria Jasin Memorial Sloan Kettering Cancer Center
Mark E. Smulson
Mark E. Smulson Georgetown University

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