What is he best known for?
The fields of study he is best known for:
His scientific interests lie mostly in DNA repair, Molecular biology, DNA replication, Homologous recombination and DNA damage.
His DNA repair study integrates concerns from other disciplines, such as Replication protein A, Cancer research and Poly ADP ribose polymerase, PARP1.
His Molecular biology study combines topics from a wide range of disciplines, such as Base excision repair, Genetic recombination, Histone code, Histone H2A and Gene conversion.
His DNA replication research includes themes of Cell cycle, Chromosome instability, Aneuploidy and Cell biology.
Thomas Helleday has researched Homologous recombination in several fields, including Gene duplication, Homology directed repair, Postreplication repair and Poly Polymerase Inhibitor.
His biological study spans a wide range of topics, including Cancer cell, Senescence, DNA fragmentation and Pharmacology.
His most cited work include:
- Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase (3289 citations)
- Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase (3289 citations)
- Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints (1500 citations)
What are the main themes of his work throughout his whole career to date?
DNA repair, DNA damage, Cancer research, Molecular biology and DNA are his primary areas of study.
His research integrates issues of Poly ADP ribose polymerase and Poly Polymerase Inhibitor in his study of DNA repair.
His DNA damage research integrates issues from G2-M DNA damage checkpoint, DNA mismatch repair, DNA replication and Cell biology.
The study incorporates disciplines such as Cancer cell, Cancer, Apoptosis, Programmed cell death and Downregulation and upregulation in addition to Cancer research.
The various areas that Thomas Helleday examines in his Molecular biology study include Replication protein A, Nucleotide excision repair, Homologous recombination and Proliferating cell nuclear antigen.
His Homologous recombination research focuses on Genetic recombination and how it connects with High-mobility group.
He most often published in these fields:
- DNA repair (58.11%)
- DNA damage (41.22%)
- Cancer research (39.41%)
What were the highlights of his more recent work (between 2018-2021)?
- Cancer research (39.41%)
- DNA (36.04%)
- DNA damage (41.22%)
In recent papers he was focusing on the following fields of study:
The scientist’s investigation covers issues in Cancer research, DNA, DNA damage, Cancer cell and Biochemistry.
Thomas Helleday interconnects Base excision repair, DNA repair, Cancer and Apoptosis in the investigation of issues within Cancer research.
His work carried out in the field of DNA repair brings together such families of science as Polymerase, Poly ADP ribose polymerase, Homologous recombination, Proteomics and Messenger RNA.
He combines subjects such as Nucleotide and Cell biology with his study of DNA.
DNA damage is frequently linked to Protein subunit in his study.
His studies in Mitosis integrate themes in fields like Cell cycle and DNA replication.
Between 2018 and 2021, his most popular works were:
- Managing COVID-19 in the oncology clinic and avoiding the distraction effect. (88 citations)
- Managing COVID-19 in the oncology clinic and avoiding the distraction effect. (88 citations)
- The DNA Damaging Revolution: PARP Inhibitors and Beyond. (60 citations)
In his most recent research, the most cited papers focused on:
Thomas Helleday mostly deals with Cancer research, DNA, DNA repair, DNA damage and Cancer cell.
His work deals with themes such as Cancer, Chemotherapy induced, Immunotherapy and Cell culture, which intersect with Cancer research.
As a part of the same scientific family, Thomas Helleday mostly works in the field of DNA, focusing on Cell biology and, on occasion, In vitro and Mechanism of action.
Thomas Helleday performs multidisciplinary study on DNA repair and Somatic hypermutation in his works.
Thomas Helleday has included themes like Poly ADP ribose polymerase and Pharmacology in his DNA damage study.
His Cancer cell study integrates concerns from other disciplines, such as Polymerase, Homologous recombination, Transcriptome, Proteomics and Messenger RNA.
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