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Per Artursson

Per Artursson

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Biology and Biochemistry
Sweden
2023

D-Index & Metrics

Biology and Biochemistry

D-Index
108
Citations
40923
World Ranking
1052
National Ranking
19

Research.com Recognitions

  • 2023 - Research.com Biology and Biochemistry in Sweden Leader Award
  • 2016 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Per Artursson is affiliated with Uppsala University in Sweden and has contributed extensively to the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their research spans a wide range of topics focused primarily on drug transport, resistance mechanisms, liver disease, and metabolism.

The scientist's main fields of study include:

  • Medicine
  • Biochemistry, Genetics and Molecular Biology

Their work notably covers subfields such as Molecular Biology, Oncology, Pharmacology, Physiology, and Epidemiology, reflecting a multidisciplinary approach to biomedical research.

Main research topics addressed by Per Artursson include:

  • Drug Transport and Resistance Mechanisms
  • Liver Disease Diagnosis and Treatment
  • Diet and Metabolism Studies
  • Pharmacogenetics and Drug Metabolism
  • Pharmacological Effects and Toxicity Studies
  • Liver Physiology and Pathology
  • Bariatric Surgery and Outcomes

Recent publications by Per Artursson highlight their focus on pharmacology and liver-related research. They contributed to the following papers:

  • "The Critical Role of Passive Permeability in Designing Successful Drugs" (2020), published in ChemMedChem
  • "Cell-type-resolved proteomic analysis of the human liver" (2020), published in Liver International
  • "Drug Disposition Protein Quantification in Matched Human Jejunum and Liver From Donors With Obesity" (2022), published in Clinical Pharmacology & Therapeutics
  • "Short- and long-term effects of body weight, calorie restriction and gastric bypass on CYP1A2, CYP2C19 and CYP2C9 activity" (2022), published in British Journal of Clinical Pharmacology
  • "Short- and long-term effects of body weight loss following calorie restriction and gastric bypass on CYP3A-activity - a non-randomized three-armed controlled trial" (2021), published in Clinical and Translational Science

The frequent co-authors collaborating with Per Artursson include Christine Wegler, Niklas Handin, Jøran Hjelmesæth, Rasmus Jansson-Löfmark, and Anders Åsberg, reflecting strong research partnerships.

The venues in which Per Artursson regularly publishes research are:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Clinical and Translational Science
  • Drug Metabolism and Pharmacokinetics
  • Clinical Pharmacology & Therapeutics
  • Pharmaceutical Research

In 2016, Per Artursson was recognized as a Fellow of the American Association for the Advancement of Science (AAAS).

Best Publications

  • Correlation between oral drug absorption in humans and apparent drug permeability coefficients in human intestinal epithelial (Caco-2) cells

    P. Artursson;J. Karlsson

  • Caco-2 monolayers in experimental and theoretical predictions of drug transport

    Per Artursson;Katrin Palm;Kristina Luthman

  • Determination of drug permeability and prediction of drug absorption in Caco-2 monolayers.

    Ina Hubatsch;Eva G E Ragnarsson;Per Artursson

  • Epithelial Transport Of Drugs In Cell Culture. I: A Model For Studying The Passive Diffusion Of Drugs Over Intestinal Absorbtive (Caco-2) Cells

    Per Artursson

  • Effect of chitosan on the permeability of monolayers of intestinal epithelial cells (Caco-2).

    Per Artursson;Tuulikki Lindmark;Stanley S. Davis;Lisbeth Illum

  • Polar Molecular Surface Properties Predict the Intestinal Absorption of Drugs in Humans

    Katrin Palm;Patric Stenberg;Kristina Luthman;Per Artursson

  • Chitosans as Absorption Enhancers for Poorly Absorbable Drugs 2: Mechanism of Absorption Enhancement

    Nicolaas G. M. Schipper;Susanne Olsson;Janet A. Hoogstraate;Albertus G. deBoer

  • Coexistence of passive and carrier-mediated processes in drug transport

    Kiyohiko Sugano;Manfred Kansy;Per Artursson;Alex Avdeef

  • Chitosan as a nonviral gene delivery system. Structure-property relationships and characteristics compared with polyethylenimine in vitro and after lung administration in vivo.

    Magnus Köping-Höggård;Ioannis Tubulekas;Holly Guan;Katarina Edwards

  • Expression of Thirty-six Drug Transporter Genes in Human Intestine, Liver, Kidney, and Organotypic Cell Lines

    Constanze Hilgendorf;Gustav Ahlin;Annick Seithel;Per Artursson

  • Correlation of gene expression of ten drug efflux proteins of the ATP-binding cassette transporter family in normal human jejunum and in human intestinal epithelial Caco-2 cell monolayers.

    Jan Taipalensuu;Hans Törnblom;Greger Lindberg;Curt Einarsson

  • Chitosans as absorption enhancers for poorly absorbable drugs. 1: Influence of molecular weight and degree of acetylation on drug transport across human intestinal epithelial (Caco-2) cells.

    Nicolaas G. M. Schipper;Kjell M. Vårum;Per Artursson

  • MTH1 inhibition eradicates cancer by preventing sanitation of the dNTP pool

    Helge Gad;Tobias Koolmeister;Ann-Sofie Jemth;Saeed Eshtad

  • Correlation of Drug Absorption with Molecular Surface Properties

    Katrin Palm;Kristina Luthman;Anna‐Lena Ungell;Gert Strandlund

  • Improved chitosan-mediated gene delivery based on easily dissociated chitosan polyplexes of highly defined chitosan oligomers

    M Köping-Höggård;KM Vårum;M Issa;S Danielsen

  • Absorption enhancement through intracellular regulation of tight junction permeability by medium chain fatty acids in Caco-2 cells.

    Tuulikki Lindmark;Yukitaka Kimura;Yukitaka Kimura;Per Artursson

  • Chitosans as absorption enhancers of poorly absorbable drugs: 3: Influence of mucus on absorption enhancement

    Nicolaas G.M. Schipper;Kjell M. Vårum;Patric Stenberg;Göran Ocklind

  • Regional levels of drug transporters along the human intestinal tract : Co-expression of ABC and SLC transporters and comparison with Caco-2 cells

    Gunilla Englund;Fredrik Rorsman;Anders Rönnblom;Urban Karlbom

  • Oral absorption of peptides and nanoparticles across the human intestine: Opportunities, limitations and studies in human tissues.

    Patrik Lundquist;Per Artursson

  • Selective paracellular permeability in two models of intestinal absorption: cultured monolayers of human intestinal epithelial cells and rat intestinal segments.

    Per Artursson;Anna-Lena Ungell;Jan-Erik Löfroth

Frequent Co-Authors

Kristina Luthman
Kristina Luthman University of Gothenburg
Jacek R. Wiśniewski
Jacek R. Wiśniewski Max Planck Society
Istvan Toth
Istvan Toth University of Queensland
Kjell M. Vårum
Kjell M. Vårum Norwegian University of Science and Technology
Tommy B. Andersson
Tommy B. Andersson AstraZeneca (United Kingdom)
Thomas Helleday
Thomas Helleday Karolinska Institute
Hans Lennernäs
Hans Lennernäs Uppsala University
György Kéri
György Kéri Semmelweis University
Alex Avdeef
Alex Avdeef in-ADME Research
Per I. Arvidsson
Per I. Arvidsson Science for Life Laboratory

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