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Medicine

D-Index
87
Citations
24626
World Ranking
13756
National Ranking
1278

Overview

Tommy B. Andersson is affiliated with AstraZeneca in the United Kingdom. Their research primarily focuses on the intersection of medicine and pharmacology, toxicology, and pharmaceutics, with significant contributions in pharmacology as a subfield. The main topics addressed in their work include pharmacogenetics and drug metabolism, drug transport and resistance mechanisms, diet and metabolism studies, pancreatic function and diabetes, drug-induced hepatotoxicity and protection, liver disease diagnosis and treatment, and pharmacology related to obesity treatment.

Andersson's recent publications span various respected journals. Notable papers include:

  • Primary Human Hepatocyte Spheroid Model as a 3D In Vitro Platform for Metabolism Studies, 2020, Journal of Pharmaceutical Sciences
  • Clinically Relevant Cytochrome P450 3A4 Induction Mechanisms and Drug Screening in Three-Dimensional Spheroid Cultures of Primary Human Hepatocytes, 2020, Clinical Pharmacology & Therapeutics
  • Correlation of Body Weight and Composition With Hepatic Activities of Cytochrome P450 Enzymes, 2020, Journal of Pharmaceutical Sciences
  • Drug Disposition Protein Quantification in Matched Human Jejunum and Liver From Donors With Obesity, 2022, Clinical Pharmacology & Therapeutics
  • Short- and long-term effects of body weight, calorie restriction and gastric bypass on CYP1A2, CYP2C19 and CYP2C9 activity, 2022, British Journal of Clinical Pharmacology

Throughout these publications, Andersson has collaborated frequently with several co-authors, including Rasmus Jansson-Löfmark, Christine Wegler, Ida Robertsen, Hege Christensen, and Jøran Hjelmesæth.

Their work is often published in journals such as the Journal of Pharmaceutical Sciences, Clinical Pharmacology & Therapeutics, bioRxiv (Cold Spring Harbor Laboratory), British Journal of Clinical Pharmacology, and Clinical and Translational Science.

Andersson's research has contributed broadly to understanding pharmacogenetics, drug metabolism, and the role of body weight and metabolism in pharmacologic processes and disease mechanisms. Their investigations into cytochrome P450 enzymes and drug disposition proteins reflect an emphasis on how physiological factors influence drug metabolism and therapeutic efficacy.

Best Publications

  • Carotid artery stenting compared with endarterectomy in patients with symptomatic carotid stenosis (International Carotid Stenting Study): an interim analysis of a randomised controlled trial

    Jörg Ederle;Joanna Dobson;Joanna Dobson;Roland L. Featherstone;Leo H. Bonati;Leo H. Bonati

  • Comparison of inhibitory effects of the proton pump-inhibiting drugs omeprazole, esomeprazole, lansoprazole, pantoprazole, and rabeprazole on human cytochrome P450 activities

    Xue-Qing Li;Tommy B. Andersson;Marie Ahlström;Lars Weidolf

  • Pharmacokinetics, metabolism and interactions of acid pump inhibitors. Focus on omeprazole, lansoprazole and pantoprazole.

    Tommy Andersson

  • Stereoselective Metabolism of Omeprazole by Human Cytochrome P450 Enzymes

    Angela Äbelö;Tommy B. Andersson;Madeleine Antonsson;Anna Knuts Naudot

  • Physiological Disturbances in Fish Living in Coastal Water Polluted with Bleached Kraft Pulp Mill Effluents

    Tommy Andersson;Lars Förlin;Jan Härdig;Åke Larsson

  • Penumbral imaging and functional outcome in patients with anterior circulation ischaemic stroke treated with endovascular thrombectomy versus medical therapy: a meta-analysis of individual patient-level data

    Bruce C V Campbell;Charles B L M Majoie;Gregory W Albers;Bijoy K Menon

  • Evaluation of HepaRG Cells as an In Vitro Model for Human Drug Metabolism Studies

    Kajsa P. Kanebratt;Tommy B. Andersson

  • Esomeprazole provides improved acid control vs. omeprazole In patients with symptoms of gastro-oesophageal reflux disease.

    Lind T;Rydberg L;Kylebäck A;Jonsson A

  • Genome-wide pharmacogenetic investigation of a hepatic adverse event without clinical signs of immunopathology suggests an underlying immune pathogenesis

    Andreas Kindmark;A Jawaid;C G Harbron;B J Barratt

  • Interindividual differences in hepatic expression of CYP3A4: relationship to genetic polymorphism in the 5'-upstream regulatory region.

    Anna Westlind;Lena Löfberg;Niclas Tindberg;Tommy B. Andersson

  • Neutrophil extracellular traps in ischemic stroke thrombi.

    Elodie Laridan;Frederik Denorme;Linda Desender;Olivier François

  • Regulation of the cytochrome P450 enzyme system in fish

    Tommy Andersson;Lars Förlin

  • Amodiaquine clearance and its metabolism to N-desethylamodiaquine is mediated by CYP2C8: a new high affinity and turnover enzyme-specific probe substrate.

    Xue-Qing Li;Anders Björkman;Tommy B. Andersson;Marianne Ridderström

  • Pharmacokinetic Studies with Esomeprazole, the (S)-Isomer of Omeprazole

    Tommy Andersson;Mohammed Hassan-Alin;Göran Hasselgren;Kerstin Röhss

  • Comparative analysis of CYP3A expression in human liver suggests only a minor role for CYP3A5 in drug metabolism.

    Anna Westlind-Johnsson;Sarah Malmebo;Anna Johansson;Charlotta Otter

  • Biology-inspired microphysiological system approaches to solve the prediction dilemma of substance testing.

    Uwe Marx;Tommy B Andersson;Anthony Bahinski;Mario Beilmann

  • Natural History of Dural Arteriovenous Shunts

    Michael Söderman;Ladislav Pavic;Göran Edner;Staffan Holmin

  • Identification of human cytochrome P(450)s that metabolise anti-parasitic drugs and predictions of in vivo drug hepatic clearance from in vitro data.

    Xue-Qing Li;Anders Björkman;Tommy B. Andersson;Lars L. Gustafsson

  • Cloning and tissue distribution of a novel human cytochrome p450 of the CYP3A subfamily, CYP3A43.

    Anna Westlind;Sarah Malmebo;Inger Johansson;Charlotta Otter

  • The HepaRG cell line: a unique in vitro tool for understanding drug metabolism and toxicology in human

    Tommy B Andersson;Kajsa P Kanebratt;John Gerry Kenna

Frequent Co-Authors

Magnus Ingelman-Sundberg
Magnus Ingelman-Sundberg Karolinska Institute
Per Artursson
Per Artursson Uppsala University
Inger Johansson
Inger Johansson Karolinska Institute
Ulf Diczfalusy
Ulf Diczfalusy Karolinska University Hospital
Albert J. Yoo
Albert J. Yoo Harvard University
Tudor G. Jovin
Tudor G. Jovin Cooper University Hospital
Antoni Dávalos
Antoni Dávalos Autonomous University of Barcelona
David S. Liebeskind
David S. Liebeskind University of California, Los Angeles
Krister Kristensson
Krister Kristensson Karolinska Institute
Bruce C.V. Campbell
Bruce C.V. Campbell Royal Melbourne Hospital

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