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Medicine

D-Index
76
Citations
20119
World Ranking
18822
National Ranking
361

Overview

Ulf Diczfalusy is affiliated with Karolinska University Hospital in Sweden. Their research primarily focuses on areas within Medicine and Pharmacology, Toxicology and Pharmaceutics, with specific attention to Pharmacology, Endocrinology, Diabetes and Metabolism, Oncology, Biochemistry, and Infectious Diseases.

The scientist's work covers several key topics, including:

  • Pharmacogenetics and Drug Metabolism
  • Hormonal Regulation and Hypertension
  • Drug Transport and Resistance Mechanisms
  • Eicosanoids and Hypertension Pharmacology
  • HIV/AIDS drug development and treatment
  • Drug-Induced Hepatotoxicity and Protection
  • Cholesterol and Lipid Metabolism

Representative papers authored or co-authored by Ulf Diczfalusy include:

  • "Pregnancy Increases CYP3A Enzymes Activity as Measured by the 4β-Hydroxycholesterol/Cholesterol Ratio," 2022, International Journal of Molecular Sciences
  • "Early or deferred initiation of efavirenz during rifampicin-based TB therapy has no significant effect on CYP3A induction in TB-HIV infected patients," 2020, British Journal of Pharmacology
  • "Evaluation of 1β-Hydroxylation of Deoxycholic Acid as a Non-Invasive Urinary Biomarker of CYP3A Activity in the Assessment of Inhibition-Based Drug-Drug Interaction in Healthy Volunteers," 2021, Journal of Personalized Medicine
  • "A sterol panel for rare lipid disorders: sitosterolemia, cerebrotendinous xanthomatosis and Smith-Lemli-Opitz syndrome," 2024, Journal of Lipid Research
  • "Studies on CYP3A activity during the menstrual cycle as measured by urinary 6β-hydroxycortisol/cortisol," 2021, Pharmacology Research & Perspectives

The scientist frequently collaborates with several co-authors, including:

  • Eleni Aklillu
  • Anita Lövgren Sandblom
  • Helena Bergström
  • Linda Björkhem-Bergman
  • Eulambius M. Mlugu

Ulf Diczfalusy's publications appear across various scientific journals such as:

  • International Journal of Molecular Sciences
  • British Journal of Pharmacology
  • Journal of Personalized Medicine
  • Journal of Lipid Research
  • Pharmacology Research & Perspectives

Best Publications

  • Strong association between malnutrition, inflammation, and atherosclerosis in chronic renal failure

    Peter Stenvinkel;Olof Heimbürger;Olof Heimbürger;Furcy Paultre;Furcy Paultre;Ulf Diczfalusy;Ulf Diczfalusy

  • Cholesterol homeostasis in human brain: evidence for an age-dependent flux of 24S-hydroxycholesterol from the brain into the circulation

    Dieter Lutjohann;Olof Breuer;Gunvor Ahlborg;Inger Nennesmo

  • Determination of Cholesterol Oxidation Products in Human Plasma by Isotope Dilution-Mass Spectrometry

    S. Dzeletovic;O. Breuer;E. Lund;U. Diczfalusy

  • Cholesterol homeostasis in human brain: turnover of 24S-hydroxycholesterol and evidence for a cerebral origin of most of this oxysterol in the circulation

    Ingemar Björkhem;Dieter Lütjohann;Ulf Diczfalusy;Lars Ståhle

  • The antioxidant butylated hydroxytoluene protects against atherosclerosis.

    I. Bjorkhem;A. Henriksson-Freyschuss;O. Breuer;U. Diczfalusy

  • Hepatic cholesterol metabolism and resistance to dietary cholesterol in LXRβ-deficient mice

    S. Alberti;G. Schuster;P. Parini;D. Feltkamp

  • Atherosclerosis and sterol 27-hydroxylase: evidence for a role of this enzyme in elimination of cholesterol from human macrophages.

    Ingemar Bjorkhem;Olof Andersson;Ulf Diczfalusy;Bo Sevastik

  • Oxysterols Friends, Foes, or Just Fellow Passengers?

    Ingemar Björkhem;Ulf Diczfalusy

  • Changes in the levels of cerebral and extracerebral sterols in the brain of patients with Alzheimer's disease

    Maura Heverin;Nenad Bogdanovic;Dieter Lütjohann;Thomas Bayer

  • Lipoprotein Oxidation and Progression of Carotid Atherosclerosis

    Jukka T. Salonen;Kristiina Nyyssonen;Riitta Salonen;Elina Porkkala-sarataho

  • Complementary stimulation of hepatobiliary transport and detoxification systems by rifampicin and ursodeoxycholic acid in humans

    Hanns—Ulrich Marschall;Martin Wagner;Gernot Zollner;Peter Fickert

  • Elimination of Cholesterol in Macrophages and Endothelial Cells by the Sterol 27-Hydroxylase Mechanism COMPARISON WITH HIGH DENSITY LIPOPROTEIN-MEDIATED REVERSE CHOLESTEROL TRANSPORT

    Amir Babiker;Olof Andersson;Erik Lund;Rui-Juan Xiu

  • Crossing the barrier: net flux of 27-hydroxycholesterol into the human brain

    Maura Heverin;Steve Meaney;Dieter Lütjohann;Ulf Diczfalusy

  • Antiepileptic Drugs Increase Plasma Levels of 4β-Hydroxycholesterolin Humans EVIDENCE FOR INVOLVEMENT OF CYTOCHROME P450 3A4

    Karl Bodin;Lionel Bretillon;Yacoub Aden;Leif Bertilsson

  • Conversion of prostaglandin endoperoxides to C17-hydroxy acids catalyzed by human platelet thromboxane synthase

    Ulf Diczfalusy;Pierre Falardeau;Sven Hammarström

  • On the turnover of brain cholesterol in patients with Alzheimer's disease. Abnormal induction of the cholesterol-catabolic enzyme CYP46 in glial cells.

    Nenad Bogdanovic;Lionel Bretillon;Erik G. Lund;Ulf Diczfalusy

  • 4β-hydroxycholesterol, an endogenous marker of CYP3A4/5 activity in humans

    Ulf Diczfalusy;Hanna Nylén;Pontus Elander;Leif Bertilsson

  • Importance of a Novel Oxidative Mechanism for Elimination of Intracellular Cholesterol in Humans

    Erik Lund;Olof Andersson;Jie Zhang;Amir Babiker

  • Metabolism of 4β-Hydroxycholesterol in Humans

    Karl Bodin;Ulla Andersson;Eva Rystedt;Ewa Ellis

  • On the rate of translocation in vitro and kinetics in vivo of the major oxysterols in human circulation: critical importance of the position of the oxygen function.

    Steve Meaney;Karl Bodin;Ulf Diczfalusy;Ingemar Björkhem

Frequent Co-Authors

Ingemar Björkhem
Ingemar Björkhem Karolinska University Hospital
Leif Bertilsson
Leif Bertilsson Karolinska University Hospital
Dieter Lütjohann
Dieter Lütjohann University Hospital Bonn
Tommy B. Andersson
Tommy B. Andersson AstraZeneca (United Kingdom)
Peter Stenvinkel
Peter Stenvinkel Karolinska Institute
Lars Berglund
Lars Berglund Royal Institute of Technology
Jan Nilsson
Jan Nilsson Lund University
Sven Hammarström
Sven Hammarström Linköping University
Kristiina Nyyssönen
Kristiina Nyyssönen University of Eastern Finland
Olof Heimbürger
Olof Heimbürger Karolinska Institute

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