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Molecular Biology

D-Index
101
Citations
31833
World Ranking
516
National Ranking
287

Research.com Recognitions

  • 1993 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Gordon L. Hager is affiliated with the National Institutes of Health in the United States. Their research primarily falls within the field of Biochemistry, Genetics and Molecular Biology, with a significant focus on Molecular Biology, Genetics, Endocrinology, Diabetes and Metabolism, Immunology, and Health, Toxicology and Mutagenesis.

Their work addresses several main topics including:

  • Estrogen and related hormone effects
  • Genomics and Chromatin Dynamics
  • Hormonal Regulation and Hypertension
  • RNA Research and Splicing
  • Adrenal Hormones and Disorders
  • Protein Degradation and Inhibitors
  • RNA and protein synthesis mechanisms

Recent publications by Gordon L. Hager highlight contributions to understanding transcription factor dynamics, gene regulation mechanisms, and cancer biology. Selected recent papers include:

  • "An intrinsically disordered region-mediated confinement state contributes to the dynamics and function of transcription factors" (2021, Molecular Cell)
  • "Mechanical Regulation of Transcription: Recent Advances" (2021, Trends in Cell Biology)
  • "Power-law behavior of transcription factor dynamics at the single-molecule level implies a continuum affinity model" (2021, Nucleic Acids Research)
  • "Extrachromosomal DNA Amplification Contributes to Small Cell Lung Cancer Heterogeneity and Is Associated with Worse Outcomes" (2023, Cancer Discovery)
  • ""Stripe" transcription factors provide accessibility to co-binding partners in mammalian genomes" (2022, Molecular Cell)

Gordon L. Hager collaborates with multiple frequent co-authors, including:

  • Diana A. Stavreva
  • Thomas A. Johnson
  • Grégory Fettweis
  • Kaustubh Wagh
  • Arpita Upadhyaya

Their publications often appear in venues such as bioRxiv (Cold Spring Harbor Laboratory), Journal of the Endocrine Society, Nucleic Acids Research, Molecular Cell, and Nature Communications.

In 1993, Gordon L. Hager was recognized as a Fellow of the American Association for the Advancement of Science (AAAS).

Best Publications

  • Chromatin accessibility pre-determines glucocorticoid receptor binding patterns

    Sam John;Peter J. Sabo;Robert E. Thurman;Myong Hee Sung

  • The Glucocorticoid Receptor: Rapid Exchange with Regulatory Sites in Living Cells

    James G. McNally;Waltraud G. Müller;Dawn Walker;Ronald Wolford

  • Steroid-dependent interaction of transcription factors with the inducible promoter of mouse mammary tumor virus in vivo.

    Michael G. Cordingley;Anna Tate Riegel;Gordon L. Hager

  • Visualization of glucocorticoid receptor translocation and intranuclear organization in living cells with a green fluorescent protein chimera

    Han Htun;Julia Barsony;Istvan Renyi;Daniel L. Gould

  • Global Nature of Dynamic Protein-Chromatin Interactions In Vivo: Three-Dimensional Genome Scanning and Dynamic Interaction Networks of Chromatin Proteins

    Robert D. Phair;Paola Scaffidi;Cem Elbi;Jaromíra Vecerová

  • Transcription Factor AP1 Potentiates Chromatin Accessibility and Glucocorticoid Receptor Binding

    Simon C. Biddie;Sam John;Pete J. Sabo;Robert E. Thurman

  • eRNAs Promote Transcription by Establishing Chromatin Accessibility at Defined Genomic Loci

    Kambiz Mousavi;Hossein Zare;Stefania Dell’Orso;Lars Grontved

  • Dynamic regulation of transcriptional states by chromatin and transcription factors

    Ty C. Voss;Gordon L. Hager

  • Transcription Factor Loading on the MMTV Promoter: A Bimodal Mechanism for Promoter Activation

    Trevor K. Archer;Philippe Lefebvre;Ronald G. Wolford;Gordon L. Hager

  • Early Th1 Cell Differentiation Is Marked by a Tfh Cell-like Transition

    Shingo Nakayamada;Yuka Kanno;Hayato Takahashi;Dragana Jankovic

  • Transcription factor access is mediated by accurately positioned nucleosomes on the mouse mammary tumor virus promoter.

    T K Archer;M G Cordingley;R G Wolford;G L Hager

  • Ultradian hormone stimulation induces glucocorticoid receptor-mediated pulses of gene transcription

    Diana A. Stavreva;Malgorzata Wiench;Sam John;Becky L. Conway-Campbell

  • NSD1 is essential for early post-implantation development and has a catalytically active SET domain

    Geetha Vani Rayasam;Olivia Wendling;Pierre-Olivier Angrand;Manuel Mark

  • Extensive chromatin remodelling and establishment of transcription factor 'hotspots' during early adipogenesis

    Rasmus Siersbæk;Ronni Nielsen;Sam John;Myong-Hee Sung

  • Fluorescence resonance energy transfer from cyan to yellow fluorescent protein detected by acceptor photobleaching using confocal microscopy and a single laser

    T. S. Karpova;C. T. Baumann;L. He;X. Wu

  • Interaction of the glucocorticoid receptor with the chromatin landscape.

    Sam John;Peter J. Sabo;Thomas A. Johnson;Myong Hee Sung

  • Glucocorticoid regulation of the Ha-MuSV p21 gene conferred by sequences from mouse mammary tumor virus.

    Ann L. Huang;Michael C. Ostrowski;Diana Berard;Gordon L. Hager

  • Transcriptional regulation of mammalian genes in vivo. A tale of two templates.

    Catharine L. Smith;Gordon L. Hager

  • Dynamic Exchange at Regulatory Elements during Chromatin Remodeling Underlies Assisted Loading Mechanism

    Ty C. Voss;R. Louis Schiltz;Myong Hee Sung;Paul M. Yen

  • Interactome Maps of Mouse Gene Regulatory Domains Reveal Basic Principles of Transcriptional Regulation

    Kyong-Rim Kieffer-Kwon;Zhonghui Tang;Ewy Mathe;Jason Qian

Frequent Co-Authors

Sam John
Sam John National Institutes of Health
Lyuba Varticovski
Lyuba Varticovski National Institutes of Health
John A. Stamatoyannopoulos
John A. Stamatoyannopoulos University of Washington
James G. McNally
James G. McNally National Institutes of Health
Tatiana S. Karpova
Tatiana S. Karpova National Institutes of Health
Stafford L. Lightman
Stafford L. Lightman University of Bristol
Susanne Mandrup
Susanne Mandrup University of Southern Denmark
Trevor K. Archer
Trevor K. Archer National Institutes of Health
William J. Rutter
William J. Rutter University of California, San Francisco
Emery H. Bresnick
Emery H. Bresnick University of Wisconsin–Madison

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