World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
145
Citations
86284
World Ranking
218
National Ranking
151

Overview

David A. Cheresh is affiliated with the University of California, San Diego in the United States. Their research primarily spans the field of medicine, with a notable focus on oncology, immunology, and molecular biology. Their work addresses various aspects of cell biology and immunology and allergy, producing a body of research that explores cancer biology, immune regulation, and cell adhesion mechanisms.

The scientist has contributed extensively to studies on cell adhesion molecules, phagocytosis and immune regulation, and cancer cells and metastasis. Other key topics covered in their work include interferon and immune responses, extracellular vesicles in disease, nanoplatforms for cancer theranostics, and monoclonal and polyclonal antibodies research.

David A. Cheresh has published numerous research articles, with frequent publication venues including:

  • Cancer Research
  • Cell Stem Cell
  • Nature Cell Biology
  • Journal of Cell Science
  • Science Translational Medicine

Some recent scientific papers authored by David A. Cheresh are:

  • "Zika Virus Targets Glioblastoma Stem Cells through a SOX2-Integrin αvβ5 Axis," 2020, Cell Stem Cell
  • "Pancreatic cancer cells upregulate LPAR4 in response to isolation stress to promote an ECM-enriched niche and support tumour initiation," 2023, Nature Cell Biology
  • "Upregulation of fibronectin and its integrin receptors - an adaptation to isolation stress that facilitates tumor initiation," 2023, Journal of Cell Science
  • "Integrin αvβ3 Upregulation in Response to Nutrient Stress Promotes Lung Cancer Cell Metabolic Plasticity," 2024, Cancer Research
  • "Tumor-initiating cells establish a niche to overcome isolation stress," 2023, Trends in Cell Biology

Their research collaborations frequently involve several co-authors, with the most frequent including:

  • Sara M. Weis
  • Hiromi I. Wettersten
  • Tami Von Schalscha
  • Ryan M. Shepard
  • Alejandro D. Campos

David A. Cheresh's work in oncology and immunology demonstrates a consistent focus on mechanisms of cancer initiation, cellular stress responses, and interactions between tumor cells and the extracellular environment. Their contributions reflect interdisciplinary approaches combining cell biology and immune regulation to better understand cancer progression and potential therapeutic targets.

Best Publications

  • Integrins in cancer: biological implications and therapeutic opportunities

    Jay S. Desgrosellier;David A. Cheresh

  • Requirement of vascular integrin alpha v beta 3 for angiogenesis

    Peter C. Brooks;Richard A. F. Clark;David A. Cheresh

  • Integrin alpha v beta 3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels

    Peter C. Brooks;Anthony M.P. Montgomery;Mauricio Rosenfeld;Ralph A. Reisfeld

  • Integrins αvβ3 and αvβ5 promote adenovirus internalization but not virus attachment

    Thomas J. Wickham;Patricia Mathias;David A. Cheresh;Glen R. Nemerow

  • Role of integrins in cell invasion and migration

    John D. Hood;David A. Cheresh

  • Localization of Matrix Metalloproteinase MMP-2 to the Surface of Invasive Cells by Interaction with Integrin αvβ3

    Peter C Brooks;Staffan Strömblad;Luraynne C Sanders;Tami L von Schalscha

  • Tumor angiogenesis: molecular pathways and therapeutic targets

    Sara M Weis;David A Cheresh

  • Definition of Two Angiogenic Pathways by Distinct αv Integrins

    Martin Friedlander;Peter C. Brooks;Robert W. Shaffer;Christine M. Kincaid

  • Regulation of Cell Motility by Mitogen-activated Protein Kinase

    Richard L. Klemke;Shuang Cai;Ana L. Giannini;Patricia J. Gallagher

  • Tumor Regression by Targeted Gene Delivery to the Neovasculature

    John D. Hood;Mark Bednarski;Ricardo Frausto;Samira Guccione

  • Antiintegrin alpha v beta 3 blocks human breast cancer growth and angiogenesis in human skin.

    Peter C. Brooks;Staffan Strömblad;Richard Klemke;Daniel Visscher

  • Detection of tumor angiogenesis in vivo by alphaVbeta3-targeted magnetic resonance imaging.

    Dorothy A. Sipkins;David A. Cheresh;Mahmood R. Kazemi;Linda M. Nevin

  • Pathophysiological consequences of VEGF-induced vascular permeability

    Sara M Weis;David A Cheresh

  • Selective requirement for Src kinases during VEGF-induced angiogenesis and vascular permeability.

    Brian P Eliceiri;Robert Paul;Pamela L Schwartzberg;John D Hood

  • The role of αv integrins during angiogenesis: insights into potential mechanisms of action and clinical development

    Brian P. Eliceiri;David A. Cheresh

  • Biosynthetic and functional properties of an Arg-Gly-Asp-directed receptor involved in human melanoma cell attachment to vitronectin, fibrinogen, and von Willebrand factor.

    D A Cheresh;R C Spiro

  • Disruption of Angiogenesis by PEX, a Noncatalytic Metalloproteinase Fragment with Integrin Binding Activity

    Peter C Brooks;Steve Silletti;Tami L von Schalscha;Martin Friedlander

  • CAS/Crk Coupling Serves as a “Molecular Switch” for Induction of Cell Migration

    Richard L. Klemke;Jie Leng;Rachel Molander;Peter C. Brooks

  • Get a ligand, get a life: integrins, signaling and cell survival.

    Dwayne G. Stupack;David A. Cheresh

  • Erratum: Integrins in cancer: biological implications and therapeutic opportunities

    Jay S. Desgrosellier;David A. Cheresh

Frequent Co-Authors

Ralph A. Reisfeld
Ralph A. Reisfeld Scripps Research Institute
Martin Friedlander
Martin Friedlander Scripps Research Institute
Dwayne G. Stupack
Dwayne G. Stupack University of California, San Diego
David D. Schlaepfer
David D. Schlaepfer University of California, San Diego
Glen R. Nemerow
Glen R. Nemerow Scripps Research Institute
Richard L. Klemke
Richard L. Klemke University of California, San Diego
Dale L. Boger
Dale L. Boger Scripps Research Institute
Stephen D. Gillies
Stephen D. Gillies MSD (United States)
Pamela L. Schwartzberg
Pamela L. Schwartzberg National Institutes of Health
Horst Kessler
Horst Kessler Technical University of Munich

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Exploring Biology and Biochemistry can open doors to diverse careers in healthcare, data management, and quality control. Many graduates find rewarding pathways in health information management and medical coding, where strong analytical skills and attention to detail are essential.

If you are considering an allied health career, it’s important to research ccs vs cpc salary differences, as salaries and opportunities vary based on certification. Medical coding also offers competitive wages; learn more about what is medical coding salary and growth prospects before you choose your path.

The job outlook for health data roles remains positive. Many wonder, is medical billing and coding in demand? The answer is yes—these roles are increasing in demand as healthcare systems expand and digitize records.

For students seeking flexibility, accredited programs are widely available online. Check out health information management schools online to find affordable and reputable degrees that can jump-start your career in this growing field.

Best Scientists Citing David A. Cheresh

Trending Scientists