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Biology and Biochemistry
Taiwan
2026

D-Index & Metrics

Biology and Biochemistry

D-Index
87
Citations
22825
World Ranking
2882
National Ranking
10

Medicine

D-Index
87
Citations
23136
World Ranking
13788
National Ranking
29

Research.com Recognitions

  • 2026 - Research.com Biology and Biochemistry in Taiwan Leader Award

Overview

Chih-Hsin Tang is affiliated with China Medical University in Taiwan and has contributed extensively to research in medicine and biochemistry, genetics, and molecular biology. Their work spans multiple subfields including molecular biology, oncology, cancer research, rheumatology, and pharmacology.

The scientist's research covers several specialized topics, with primary focus areas such as osteoarthritis treatment and mechanisms, cytokine signaling pathways and interactions, cancer-related molecular mechanisms research, bone metabolism and diseases, microRNA in disease regulation, adipokines related to inflammation and metabolic diseases, and cell adhesion molecules research.

Chih-Hsin Tang's recent papers include:

  • Hesperidin Is a Potential Inhibitor against SARS-CoV-2 Infection (2021), published in Nutrients
  • Tetramethylpyrazine reverses high-glucose induced hypoxic effects by negatively regulating HIF-1α induced BNIP3 expression to ameliorate H9c2 cardiomyoblast apoptosis (2020), published in Nutrition & Metabolism
  • Noggin Inhibits IL-1β and BMP-2 Expression, and Attenuates Cartilage Degeneration and Subchondral Bone Destruction in Experimental Osteoarthritis (2020), published in Cells
  • Soya-cerebroside inhibits VEGF-facilitated angiogenesis in endothelial progenitor cells (2020), published in Food and Agricultural Immunology
  • Betulin suppresses TNF-α and IL-1β production in osteoarthritis synovial fibroblasts by inhibiting the MEK/ERK/NF-κB pathway (2021), published in Journal of Functional Foods

Frequent collaborators of Chih-Hsin Tang include:

  • Chun-Hao Tsai (54 coauthored publications)
  • Shan-Chi Liu (47 coauthored publications)
  • Yi-Chin Fong (42 coauthored publications)
  • Chih-Yang Lin (28 coauthored publications)
  • Yen-You Lin (26 coauthored publications)

Prominent publication venues for the scientist are:

  • International Journal of Molecular Sciences (15 publications)
  • Aging (14 publications)
  • International Journal of Biological Sciences (13 publications)
  • Cells (11 publications)
  • International Journal of Medical Sciences (11 publications)

Best Publications

  • Adiponectin Enhances IL-6 Production in Human Synovial Fibroblast via an AdipoR1 Receptor, AMPK, p38, and NF-κB Pathway

    Chih-Hsin Tang;Yung-Cheng Chiu;Tzu-Wei Tan;Rong-Sen Yang

  • Ultrasound Stimulates Cyclooxygenase-2 Expression and Increases Bone Formation through Integrin, Focal Adhesion Kinase, Phosphatidylinositol 3-Kinase, and Akt Pathway in Osteoblasts

    Chih Hsin Tang;Rong Sen Yang;Tsang Hai Huang;Dah Yuu Lu

  • CCL5 increases lung cancer migration via PI3K, Akt and NF-κB pathways

    Chun-Yin Huang;Yi-Chin Fong;Chun-Yi Lee;Meng-Yi Chen

  • Leptin-Induced IL-6 Production Is Mediated by Leptin Receptor, Insulin Receptor Substrate-1, Phosphatidylinositol 3-Kinase, Akt, NF-κB, and p300 Pathway in Microglia

    Chih-Hsin Tang;Da-Yuu Lu;Rong-Sen Yang;Huei-Yann Tsai

  • Berberine suppresses neuroinflammatory responses through AMP-activated protein kinase activation in BV-2 microglia

    Dah-Yuu Lu;Chih-Hsin Tang;Yi-Hung Chen;I-Hua Wei

  • Leptin induces IL-8 expression via leptin receptor, IRS-1, PI3K, Akt cascade and promotion of NF-κB/p300 binding in human synovial fibroblasts

    Kwok-Man Tong;Dong-Chen Shieh;Chao-Ping Chen;Chung-Yuh Tzeng

  • Involvement of matrix metalloproteinase-9 in stromal cell-derived factor-1/CXCR4 pathway of lung cancer metastasis.

    Chih-Hsin Tang;Tzu-Wei Tan;Wen-Mei Fu;Rong-Sen Yang

  • Implications of Angiogenesis Involvement in Arthritis

    Iona J. MacDonald;Shan-Chi Liu;Chen-Ming Su;Yu-Han Wang

  • Naringin-induced bone morphogenetic protein-2 expression via PI3K, Akt, c-Fos/c-Jun and AP-1 pathway in osteoblasts.

    Jin-Bin Wu;Yi-Chin Fong;Huei-Yann Tsai;Yuh-Fung Chen

  • CCL5/CCR5 axis induces vascular endothelial growth factor-mediated tumor angiogenesis in human osteosarcoma microenvironment.

    Shih-Wei Wang;Shih-Chia Liu;Hui-Lung Sun;Te-Yang Huang

  • SDF-1alpha up-regulates interleukin-6 through CXCR4, PI3K/Akt, ERK, and NF-kappaB-dependent pathway in microglia.

    Dah-Yuu Lu;Chih-Hsin Tang;Wei-Lan Yeh;Kar-Lok Wong

  • Osteopontin increases lung cancer cells migration via activation of the αvβ3 integrin/FAK/Akt and NF-κB-dependent pathway

    Yi Chin Fong;Shan Chi Liu;Chun Yin Huang;Te Mao Li

  • Osteopontin increases migration and MMP-9 up-regulation via αvβ3 integrin, FAK, ERK, and NF-κB-dependent pathway in human chondrosarcoma cells†

    Ying-Ju Chen;Ying-Ying Wei;Hsien-Te Chen;Yi-Chin Fong

  • Endothelin-1 promotes vascular endothelial growth factor-dependent angiogenesis in human chondrosarcoma cells.

    M. H. Wu;C. Y. Huang;C. Y. Huang;J. A. Lin;S. W. Wang

  • Kaempferol reduces matrix metalloproteinase-2 expression by down-regulating ERK1/2 and the activator protein-1 signaling pathways in oral cancer cells.

    Chiao-Wen Lin;Pei-Ni Chen;Mu-Kuan Chen;Wei-En Yang

  • Hypoxia-induced iNOS expression in microglia is regulated by the PI3-kinase/Akt/mTOR signaling pathway and activation of hypoxia inducible factor-1α

    Dah-Yuu Lu;Houng-Chi Liou;Chih-Hsin Tang;Wen-Mei Fu

  • Enhancement of bone morphogenetic protein-2 expression and bone formation by coumarin derivatives via p38 and ERK-dependent pathway in osteoblasts.

    Chih-Hsin Tang;Rong-Sen Yang;Mei-Yin Chien;Chien-Chich Chen

  • Regulation by ultrasound treatment on the integrin expression and differentiation of osteoblasts

    Rong Sen Yang;Win Li Lin;Ying Zhen Chen;Chih Hsin Tang

  • CCL5/CCR5 axis promotes the motility of human oral cancer cells.

    Jing-Yuan Chuang;Wei-Hung Yang;Hsien-Te Chen;Hsien-Te Chen;Chun-Yin Huang

  • CYR61 regulates BMP-2-dependent osteoblast differentiation through the αvβ3 integrin/integrin-linked kinase/ERK pathway

    Jen-Liang Su;Jean Chiou;Chih-Hsin Tang;Ming Zhao

Frequent Co-Authors

Fuu Jen Tsai
Fuu Jen Tsai China Medical University
Chang Hai Tsai
Chang Hai Tsai Asian University
Yang Chang Wu
Yang Chang Wu China Medical University
Jing Gung Chung
Jing Gung Chung China Medical University
Jai Sing Yang
Jai Sing Yang China Medical University
Sheng-Chu Kuo
Sheng-Chu Kuo China Medical University
Jer-Yuarn Wu
Jer-Yuarn Wu Academia Sinica
Tur-Fu Huang
Tur-Fu Huang National Taiwan University
Cheng Wen Lin
Cheng Wen Lin China Medical University
Jason T.C. Tzen
Jason T.C. Tzen National Chung Hsing University

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