Kwang Seok Ahn

Overview

Best Publications

• Curcumin, demethoxycurcumin, bisdemethoxycurcumin, tetrahydrocurcumin and turmerones differentially regulate anti-inflammatory and anti-proliferative responses through a ROS-independent mechanism

  Santosh K. Sandur;Manoj K. Pandey;Bokyung Sung;Kwang Seok Ahn

  810
  Citations

• The Role of Resveratrol in Cancer Therapy

  Jeong-Hyeon Ko;Gautam Sethi;Jae-Young Um;Muthu K Shanmugam

  655
  Citations

• Targeting Signal‐Transducer‐and‐Activator‐of‐Transcription‐3 for Prevention and Therapy of Cancer

  Bharat B. Aggarwal;Gautam Sethi;Kwang Seok Ahn;Santosh K. Sandur

  596
  Citations

• Natural products as a gold mine for arthritis treatment

  Dinesh Khanna;Gautam Sethi;Kwang Seok Ahn;Manoj K Pandey

  492
  Citations

• Plumbagin (5-Hydroxy-2-methyl-1,4-naphthoquinone) Suppresses NF-κB Activation and NF-κB-regulated Gene Products Through Modulation of p65 and IκBα Kinase Activation, Leading to Potentiation of Apoptosis Induced by Cytokine and Chemotherapeutic Agents

  Santosh K. Sandur;Haruyo Ichikawa;Gautam Sethi;Kwang Seok Ahn

  454
  Citations

• Celastrol, a novel triterpene, potentiates TNF-induced apoptosis and suppresses invasion of tumor cells by inhibiting NF-κB–regulated gene products and TAK1-mediated NF-κB activation

  Gautam Sethi;Kwang Seok Ahn;Manoj K. Pandey;Bharat B. Aggarwal

  445
  Citations

• β-Caryophyllene oxide inhibits growth and induces apoptosis through the suppression of PI3K/AKT/mTOR/S6K1 pathways and ROS-mediated MAPKs activation

  Kyung-Ran Park;Dongwoo Nam;Hyung-Mun Yun;Seok-Geun Lee

  395
  Citations

• Targeting Nuclear Factor-κB Activation Pathway by Thymoquinone: Role in Suppression of Antiapoptotic Gene Products and Enhancement of Apoptosis

  Gautam Sethi;Kwang Seok Ahn;Bharat B. Aggarwal

  387
  Citations

• γ-Tocotrienol Inhibits Nuclear Factor-κB Signaling Pathway through Inhibition of Receptor-interacting Protein and TAK1 Leading to Suppression of Antiapoptotic Gene Products and Potentiation of Apoptosis

  Kwang Seok Ahn;Gautam Sethi;Koyamangalath Krishnan;Bharat B. Aggarwal

  363
  Citations

• Inhibition of inducible nitric oxide synthase and cyclooxygenase II by Platycodon grandiflorum saponins via suppression of nuclear factor-κB activation in RAW 264.7 cells

  Kwang Seok Ahn;Eun Jung Noh;Hai Lin Zhao;Sang Hoon Jung

  359
  Citations

• Anacardic acid (6-nonadecyl salicylic acid), an inhibitor of histone acetyltransferase, suppresses expression of nuclear factor-κB–regulated gene products involved in cell survival, proliferation, invasion, and inflammation through inhibition of the inhibitory subunit of nuclear factor-κBα kinase, leading to potentiation of apoptosis

  Bokyung Sung;Manoj K. Pandey;Kwang Seok Ahn;Tingfang Yi

  338
  Citations

• Potential role of signal transducer and activator of transcription (STAT)3 signaling pathway in inflammation, survival, proliferation and invasion of hepatocellular carcinoma.

  Aruljothi Subramaniam;Muthu K. Shanmugam;Ekambaram Perumal;Feng Li

  338
  Citations

• Ursolic Acid Inhibits STAT3 Activation Pathway Leading to Suppression of Proliferation and Chemosensitization of Human Multiple Myeloma Cells

  Ashutosh K. Pathak;Manisha Bhutani;Asha S. Nair;Kwang Seok Ahn

  308
  Citations

• Gambogic acid, a novel ligand for transferrin receptor, potentiates TNF-induced apoptosis through modulation of the nuclear factor-κB signaling pathway

  Manoj K. Pandey;Bokyung Sung;Kwang Seok Ahn;Ajaikumar B. Kunnumakkara

  299
  Citations

• Targeted abrogation of diverse signal transduction cascades by emodin for the treatment of inflammatory disorders and cancer

  Deepti Shrimali;Muthu K. Shanmugam;Alan Prem Kumar;Jingwen Zhang

  284
  Citations

• Targeting transcription factor STAT3 for cancer prevention and therapy.

  Edna Zhi Pei Chai;Muthu K. Shanmugam;Frank Arfuso;Arunasalam Dharmarajan

  272
  Citations

• Cancer prevention and therapy through the modulation of transcription factors by bioactive natural compounds

  Muthu K Shanmugam;Jong Hyun Lee;Edna Zhi Pei Chai;Madhu Mathi Kanchi

  224
  Citations

• Embelin, an Inhibitor of X Chromosome-Linked Inhibitor-of-Apoptosis Protein, Blocks Nuclear Factor-κB (NF-κB) Signaling Pathway Leading to Suppression of NF-κB-Regulated Antiapoptotic and Metastatic Gene Products

  Kwang Seok Ahn;Gautam Sethi;Bharat B. Aggarwal

  223
  Citations

• Modification of the cysteine residues in IκBα kinase and NF-κB (p65) by xanthohumol leads to suppression of NF-κB-regulated gene products and potentiation of apoptosis in leukemia cells

  Kuzhuvelil B. Harikumar;Ajaikumar B. Kunnumakkara;Kwang S. Ahn;Preetha Anand

  218
  Citations

• Ginkgolic Acid Inhibits Invasion and Migration and TGF-β-Induced EMT of Lung Cancer Cells Through PI3K/Akt/mTOR Inactivation.

  Seung Ho Baek;Jeong-Hyeon Ko;Jong Hyun Lee;Chulwon Kim

  202
  Citations