Christopher E. Rudd

Research.com Recognitions

• 2023 - Research.com Biology and Biochemistry in Canada Leader Award

Overview

Best Publications

• CD28 and CTLA-4 coreceptor expression and signal transduction.

  Christopher E. Rudd;Alison Taylor;Helga Schneider

  1067
  Citations

• The CD4 receptor is complexed in detergent lysates to a protein-tyrosine kinase (pp58) from human T lymphocytes

  Christopher E. Rudd;James M. Trevillyan;Jai Dev Dasgupta;Linda L. Wong

  954
  Citations

• CEACAM1 regulates TIM-3-mediated tolerance and exhaustion

  Yu-Hwa Huang;Chen Zhu;Yasuyuki Kondo;Ana C. Anderson

  751
  Citations

• Reversal of the TCR stop signal by CTLA-4.

  Helga Schneider;Helga Schneider;Jos Downey;Andrew Smith;Bernd H. Zinselmeyer;Bernd H. Zinselmeyer

  738
  Citations

• The CD28-Related Molecule ICOS Is Required for Effective T Cell–Dependent Immune Responses

  Anthony J Coyle;Sophie Lehar;Clare Lloyd;Jane Tian

  703
  Citations

• The CD4 and CD8 antigens are coupled to a protein-tyrosine kinase (p56lck) that phosphorylates the CD3 complex.

  Elizabeth K. Barber;Jai Dev Dasgupta;Stuart F. Schlossman;James M. Trevillyan

  647
  Citations

• Unifying concepts in CD28, ICOS and CTLA4 co-receptor signalling.

  Christopher E. Rudd;Helga Schneider

  481
  Citations

• T-cell antigen CD28 interacts with the lipid kinase phosphatidylinositol 3-kinase by a cytoplasmic Tyr(P)-Met-Xaa-Met motif

  K. V S Prasad;Yun Cai Cai;Monika Raab;Brian Duckworth

  389
  Citations

• Cloning of a novel T-cell protein FYB that binds FYN and SH2-domain-containing leukocyte protein 76 and modulates interleukin 2 production

  A J da Silva;Z Li;C de Vera;E Canto

  331
  Citations

• Positive regulation of T cell activation and integrin adhesion by the adapter Fyb/Slap.

  Emily K. Griffiths;Connie Krawczyk;Connie Krawczyk;Young-Yun Kong;Young-Yun Kong;Monika Raab

  328
  Citations

• Upstream-downstream: CD28 cosignaling pathways and T cell function.

  Christopher E Rudd

  292
  Citations

• Regulation of Vav–SLP-76 Binding by ZAP-70 and Its Relevance to TCRζ/CD3 Induction of Interleukin-2

  Monika Raab;Antonio J.da Silva;Paul R. Findell;Christopher E. Rudd

  276
  Citations

• Adaptors and Molecular Scaffolds in Immune Cell Signaling

  Christopher E. Rudd

  276
  Citations

• 1F7, A novel cell surface molecule, involved in helper function of CD4 cells

  C Morimoto;Y Torimoto;G Levinson;C E Rudd

  247
  Citations

• p56Lck and p59Fyn regulate CD28 binding to phosphatidylinositol 3-kinase, growth factor receptor-bound protein GRB-2, and T cell-specific protein-tyrosine kinase ITK: implications for T-cell costimulation

  Monika Raab;Yun-Cai Cai;Stephen C. Bunnell;Stephanie D. Heyeck

  242
  Citations

• Cd4, cd8 and the tcr-cd3 complex: a novel class of protein-tyrosine kinase receptor

  Christopher E Rudd

  238
  Citations

• Two-step TCRζ/CD3-CD4 and CD28 signaling in T cells: SH2/SH3 domains, protein-tyrosine and lipid kinases

  Christopher E. Rudd;Ottmar Janssen;Yun Cai Cai;Antonio J. da Silva

  234
  Citations

• Src-homology 3 domain of protein kinase p59fyn mediates binding to phosphatidylinositol 3-kinase in T cells

  Kanteti V. S. Prasad;Ottmar Janssen;Rosana Kapeller;Monika Raab

  228
  Citations

• CTLA-4 binding to the lipid kinase phosphatidylinositol 3-kinase in T cells

  Helga Schneider;K. V S Prasad;Steven E. Shoelson;Christopher E. Rudd

  207
  Citations

• SH3 domain recognition of a proline-independent tyrosine-based RKxxYxxY motif in immune cell adaptor SKAP55.

  Hyun Kang;Christian Freund;Jonathan S. Duke‐Cohan;Andrea Musacchio

  202
  Citations